Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386221567> ?p ?o ?g. }
- W4386221567 abstract "ABSTRACT Complete movement arrest has recently been reported to be induced in rodents by optogenetic stimulation of a subpopulation within the pedunculopontine nucleus (PPN). This evoked arrest appears conspicuously similar to freezing behavior often seen as a fear response in prey animals but could also be akin to the freezing of gait, which is a symptom of Parkinson’s disease. This introduces two perspectives on the functional roles of this sub-region: A hub for orchestrating fear-related responses or an omnipotent halting mechanism devoid of emotional components. To better understand this phenomenon and its cognitive component, we engage the distinct electrical brain activity, the hippocampal theta rhythm. This rhythm has a well-described contextual association between various aspects of cognition and behavior. It is prominent during locomotor activity in rodents and immobile yet aroused states like behavioral freezing. We recorded the electrical activity in the hippocampus of rats while walking and being arrested by PPN stimulation. A clear obstruction of the ongoing theta activity was associated with the motor arrest. The timescale of movement arrest was less than 200 ms, similar to the obstruction of the theta rhythm. Since, anxiety, fear, and behavioral freezing are associated with hippocampal theta rhythm, which we did not see during PPN stimulation, we suggest the induced motor arrest occurs without an associated emotional component." @default.
- W4386221567 created "2023-08-29" @default.
- W4386221567 creator A5002564778 @default.
- W4386221567 creator A5027926308 @default.
- W4386221567 creator A5029885731 @default.
- W4386221567 creator A5032439531 @default.
- W4386221567 creator A5060357008 @default.
- W4386221567 creator A5092707888 @default.
- W4386221567 date "2023-08-27" @default.
- W4386221567 modified "2023-10-18" @default.
- W4386221567 title "Arrest of movement induced by Pedunculopontine-stimulation obstructs hippocampal theta rhythm" @default.
- W4386221567 cites W1568903867 @default.
- W4386221567 cites W1583270247 @default.
- W4386221567 cites W1791529270 @default.
- W4386221567 cites W1973372728 @default.
- W4386221567 cites W1988399537 @default.
- W4386221567 cites W1990441521 @default.
- W4386221567 cites W2001509348 @default.
- W4386221567 cites W2003260420 @default.
- W4386221567 cites W2022050193 @default.
- W4386221567 cites W2037027052 @default.
- W4386221567 cites W2042789025 @default.
- W4386221567 cites W2049289902 @default.
- W4386221567 cites W2056336718 @default.
- W4386221567 cites W2071751312 @default.
- W4386221567 cites W2072434780 @default.
- W4386221567 cites W2072843066 @default.
- W4386221567 cites W2080275925 @default.
- W4386221567 cites W2083550321 @default.
- W4386221567 cites W2084694708 @default.
- W4386221567 cites W2087575813 @default.
- W4386221567 cites W2089141705 @default.
- W4386221567 cites W2106108170 @default.
- W4386221567 cites W2109154368 @default.
- W4386221567 cites W2143461176 @default.
- W4386221567 cites W2150951291 @default.
- W4386221567 cites W2172956247 @default.
- W4386221567 cites W2262104398 @default.
- W4386221567 cites W2274915531 @default.
- W4386221567 cites W2339071900 @default.
- W4386221567 cites W2346950464 @default.
- W4386221567 cites W2396921559 @default.
- W4386221567 cites W2399631956 @default.
- W4386221567 cites W2411929111 @default.
- W4386221567 cites W2465591226 @default.
- W4386221567 cites W2551836638 @default.
- W4386221567 cites W2573855591 @default.
- W4386221567 cites W2592528122 @default.
- W4386221567 cites W2594106885 @default.
- W4386221567 cites W2604970372 @default.
- W4386221567 cites W2778169119 @default.
- W4386221567 cites W2782777427 @default.
- W4386221567 cites W2785406730 @default.
- W4386221567 cites W2790261399 @default.
- W4386221567 cites W2802543563 @default.
- W4386221567 cites W2898311060 @default.
- W4386221567 cites W2919574227 @default.
- W4386221567 cites W2939535752 @default.
- W4386221567 cites W2952471063 @default.
- W4386221567 cites W2966752492 @default.
- W4386221567 cites W2972514463 @default.
- W4386221567 cites W3084283750 @default.
- W4386221567 cites W3091939023 @default.
- W4386221567 cites W3119819356 @default.
- W4386221567 cites W3128393435 @default.
- W4386221567 cites W3134475547 @default.
- W4386221567 cites W3185690618 @default.
- W4386221567 cites W3194243343 @default.
- W4386221567 cites W3207257789 @default.
- W4386221567 cites W4205125105 @default.
- W4386221567 cites W4229369167 @default.
- W4386221567 cites W4243615572 @default.
- W4386221567 cites W4281298803 @default.
- W4386221567 cites W4289524097 @default.
- W4386221567 cites W4293493786 @default.
- W4386221567 cites W4303022253 @default.
- W4386221567 cites W4304780387 @default.
- W4386221567 cites W4312215232 @default.
- W4386221567 cites W4365143757 @default.
- W4386221567 cites W4378173257 @default.
- W4386221567 cites W4385302678 @default.
- W4386221567 doi "https://doi.org/10.1101/2023.08.26.554923" @default.
- W4386221567 hasPublicationYear "2023" @default.
- W4386221567 type Work @default.
- W4386221567 citedByCount "0" @default.
- W4386221567 crossrefType "posted-content" @default.
- W4386221567 hasAuthorship W4386221567A5002564778 @default.
- W4386221567 hasAuthorship W4386221567A5027926308 @default.
- W4386221567 hasAuthorship W4386221567A5029885731 @default.
- W4386221567 hasAuthorship W4386221567A5032439531 @default.
- W4386221567 hasAuthorship W4386221567A5060357008 @default.
- W4386221567 hasAuthorship W4386221567A5092707888 @default.
- W4386221567 hasBestOaLocation W43862215671 @default.
- W4386221567 hasConcept C126322002 @default.
- W4386221567 hasConcept C135343436 @default.
- W4386221567 hasConcept C148762608 @default.
- W4386221567 hasConcept C15744967 @default.
- W4386221567 hasConcept C169760540 @default.
- W4386221567 hasConcept C169900460 @default.
- W4386221567 hasConcept C24998067 @default.