FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386222695> ?p ?o ?g. }

• W4386222695 endingPage "2386" @default.
• W4386222695 startingPage "2386" @default.
• W4386222695 abstract "Prostate cancer treatment poses significant challenges due to its varying aggressiveness, potential for metastasis, and the complexity of treatment options. Balancing the effectiveness of therapies, minimizing side effects, and personalizing treatment strategies are ongoing challenges in managing this disease. Significant advances in the use of nanotechnology for the treatment of prostate cancer with high specificity, sensitivity, and efficacy have recently been made. This study aimed to synthesize and characterize a novel Cu/Fe layer double hydroxide (LDH) nanocomposite for use as an anticancer agent to treat prostate cancer. Cu/Fe LDH nanocomposites with a molar ratio of 5:1 were developed using a simple co-precipitation approach. FT-IR, XRD, SEM, TEM, TGA, and zeta potential analyses confirmed the nanocomposite. Moreover, the MTT cell viability assay, scratch assay, and flow cytometry were utilized to examine the prospective anticancer potential of Cu/Fe LDH on a prostate cancer (PC-3) cell line. We found that Cu/Fe LDH reduced cell viability, inhibited cell migration, induced G1/S phase cell cycle arrest, and triggered apoptotic effect in prostate cancer cells. The findings also indicated that generating reactive oxygen species (ROS) formation could improve the biological activity of Cu/Fe LDH. Additionally, Cu/Fe LDH showed a good safety impact on the normal lung fibroblast cell line (WI-38). Collectively, these findings demonstrate that the Cu/Fe LDH nanocomposite exhibited significant anticancer activities against PC-3 cells and, hence, could be used as a promising strategy in prostate cancer treatment." @default.
• W4386222695 created "2023-08-29" @default.
• W4386222695 creator A5001277106 @default.
• W4386222695 creator A5017017398 @default.
• W4386222695 creator A5032580152 @default.
• W4386222695 creator A5033320075 @default.
• W4386222695 creator A5036894308 @default.
• W4386222695 creator A5052412933 @default.
• W4386222695 creator A5062652662 @default.
• W4386222695 creator A5063694655 @default.
• W4386222695 creator A5071502750 @default.
• W4386222695 date "2023-08-25" @default.
• W4386222695 modified "2023-10-17" @default.
• W4386222695 title "A New Cu/Fe Layer Double Hydroxide Nanocomposite Exerts Anticancer Effects against PC-3 Cells by Inducing Cell Cycle Arrest and Apoptosis" @default.
• W4386222695 cites W1919158486 @default.
• W4386222695 cites W2002915481 @default.
• W4386222695 cites W2045427372 @default.
• W4386222695 cites W2054671840 @default.
• W4386222695 cites W2076298907 @default.
• W4386222695 cites W2083075306 @default.
• W4386222695 cites W2107511096 @default.
• W4386222695 cites W2112760492 @default.
• W4386222695 cites W2114918609 @default.
• W4386222695 cites W2115788076 @default.
• W4386222695 cites W2119153777 @default.
• W4386222695 cites W2123829889 @default.
• W4386222695 cites W2136906178 @default.
• W4386222695 cites W2152493648 @default.
• W4386222695 cites W2169979796 @default.
• W4386222695 cites W2170870541 @default.
• W4386222695 cites W2286120880 @default.
• W4386222695 cites W2290605528 @default.
• W4386222695 cites W2312593782 @default.
• W4386222695 cites W2320589001 @default.
• W4386222695 cites W2432268284 @default.
• W4386222695 cites W2518642608 @default.
• W4386222695 cites W2537543220 @default.
• W4386222695 cites W2580515426 @default.
• W4386222695 cites W2584835813 @default.
• W4386222695 cites W2792413160 @default.
• W4386222695 cites W2804819848 @default.
• W4386222695 cites W2891448170 @default.
• W4386222695 cites W2898384778 @default.
• W4386222695 cites W2899301603 @default.
• W4386222695 cites W2908318203 @default.
• W4386222695 cites W2941901184 @default.
• W4386222695 cites W2944440586 @default.
• W4386222695 cites W2944604858 @default.
• W4386222695 cites W2955693300 @default.
• W4386222695 cites W2970145485 @default.
• W4386222695 cites W2982570058 @default.
• W4386222695 cites W3000237215 @default.
• W4386222695 cites W3001312921 @default.
• W4386222695 cites W3003485318 @default.
• W4386222695 cites W3036239514 @default.
• W4386222695 cites W3049411042 @default.
• W4386222695 cites W3118707229 @default.
• W4386222695 cites W3119005666 @default.
• W4386222695 cites W3134346117 @default.
• W4386222695 cites W3144163177 @default.
• W4386222695 cites W3157638446 @default.
• W4386222695 cites W3176236709 @default.
• W4386222695 cites W3183350915 @default.
• W4386222695 cites W4200093095 @default.
• W4386222695 cites W4223895211 @default.
• W4386222695 cites W4283582865 @default.
• W4386222695 doi "https://doi.org/10.3390/biomedicines11092386" @default.
• W4386222695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37760826" @default.
• W4386222695 hasPublicationYear "2023" @default.
• W4386222695 type Work @default.
• W4386222695 citedByCount "0" @default.
• W4386222695 crossrefType "journal-article" @default.
• W4386222695 hasAuthorship W4386222695A5001277106 @default.
• W4386222695 hasAuthorship W4386222695A5017017398 @default.
• W4386222695 hasAuthorship W4386222695A5032580152 @default.
• W4386222695 hasAuthorship W4386222695A5033320075 @default.
• W4386222695 hasAuthorship W4386222695A5036894308 @default.
• W4386222695 hasAuthorship W4386222695A5052412933 @default.
• W4386222695 hasAuthorship W4386222695A5062652662 @default.
• W4386222695 hasAuthorship W4386222695A5063694655 @default.
• W4386222695 hasAuthorship W4386222695A5071502750 @default.
• W4386222695 hasBestOaLocation W43862226951 @default.
• W4386222695 hasConcept C121608353 @default.
• W4386222695 hasConcept C126322002 @default.
• W4386222695 hasConcept C171250308 @default.
• W4386222695 hasConcept C178790620 @default.
• W4386222695 hasConcept C185592680 @default.
• W4386222695 hasConcept C190283241 @default.
• W4386222695 hasConcept C192562407 @default.
• W4386222695 hasConcept C203014093 @default.
• W4386222695 hasConcept C2775896084 @default.
• W4386222695 hasConcept C2780192828 @default.
• W4386222695 hasConcept C29537977 @default.
• W4386222695 hasConcept C502942594 @default.
• W4386222695 hasConcept C53227056 @default.
• W4386222695 hasConcept C553184892 @default.
• W4386222695 hasConcept C55493867 @default.
• W4386222695 hasConcept C71924100 @default.

• next