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- W4386224207 abstract "Patients with Crohn’s disease can present with a variety of clinical manifestations; treatment strategies should focus on long-term remission and improvement of quality of life. There is no standardized process of diagnosing, predicting prognosis, and treating the disease. This narrative review was based on a literature search using PubMed, Embase, and Science Direct. Data on unmet challenges in patients with Crohn’s disease were extracted from identified manuscripts. The aim was to discuss present research on standardized processes in the management of patients with Crohn’s disease and to identify the unmet needs in clinical evaluation and treatment approaches. There is no consensus on standardized diagnostic, treatment, and surveillance algorithms, particularly in assessing complications of Crohn’s, such as stricturing disease, intestinal cancer risk, and cutaneous manifestations. Complications and treatment failure rates of conventional, interventional, and surgical therapy place emphasis on the need for standardized treatment algorithms, particularly in the case of acute complications of the disease. Research on standardized clinical approaches, reliable biomarkers for disease diagnosis and therapy monitoring, and new treatment agents is necessary to improve therapy and reduce complications in patients with Crohn’s disease." @default.
- W4386224207 created "2023-08-29" @default.
- W4386224207 creator A5000357211 @default.
- W4386224207 creator A5004851412 @default.
- W4386224207 creator A5009507765 @default.
- W4386224207 creator A5075770999 @default.
- W4386224207 date "2023-08-27" @default.
- W4386224207 modified "2023-10-14" @default.
- W4386224207 title "Unmet Challenges in Patients with Crohn’s Disease" @default.
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