FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386229218> ?p ?o ?g. }

• W4386229218 endingPage "2717" @default.
• W4386229218 startingPage "2717" @default.
• W4386229218 abstract "Acute hypoxia is a common abiotic stress in commercial aquaculture and has significant effects on fish physiology and metabolism. Due to its large size and rapid growth, the greater amberjack (Seriola dumerili) is an economically important fish with high farming value. This species is intolerant to hypoxia, which makes it susceptible to mass mortality and hinders the progress of amberjack cultivation. Based on a comparative analysis of the liver transcriptome between acute hypoxia-tolerant (HT) and -intolerant (HS) groups, this study first explored the molecular mechanisms of acute hypoxia in greater amberjack. By simulating the acute hypoxic environment and using RNA sequencing (RNA-Seq), the differences in liver transcriptional changes between the acute hypoxia-tolerant (HT) and hypoxia-intolerant (HS) groups of greater amberjack were probed. Based on differential expression analysis, 829 differentially expressed genes (DEGs) were screened in both groups. Relative to the HS group, 374 DEGs were upregulated and 455 were downregulated in the HT group. Compared with the HS group, genes such as slc2a5 and prkaa2 related to promoting sugar transport and inhibiting lipid syntheses were upregulated, while genes that inhibit gluconeogenesis and promote lipid syntheses, such as pgp and aacs, were downregulated. The expression of odc1 was significantly and relatively downregulated in the HT group, which would lead to the inhibition of intracellular antioxidant activity and decreased scavenging of ROS. The NF-kB pathway was also promoted to some extent in individuals in the HT group relative to the HS group to resist apoptosis. In addition, the relative downregulation of apoptosis and autophagy-related genes, such as endog, hm13, and casp6, was also detected in the HT group. The present findings first reported the regulation mechanism by which liver tissue coped with the acute hypoxia stress in greater amberjack, which will provide important technical support for preventing acute hypoxia-induced death in advance and reducing economic losses." @default.
• W4386229218 created "2023-08-29" @default.
• W4386229218 creator A5006069022 @default.
• W4386229218 creator A5012937541 @default.
• W4386229218 creator A5015690491 @default.
• W4386229218 creator A5019595634 @default.
• W4386229218 creator A5027037635 @default.
• W4386229218 creator A5033367677 @default.
• W4386229218 creator A5049692788 @default.
• W4386229218 creator A5080308075 @default.
• W4386229218 creator A5083455588 @default.
• W4386229218 date "2023-08-26" @default.
• W4386229218 modified "2023-10-01" @default.
• W4386229218 title "Liver Transcriptome Shows Differences between Acute Hypoxia-Tolerant and Intolerant Individuals of Greater Amberjack (Seriola dumerili)" @default.
• W4386229218 cites W1538332940 @default.
• W4386229218 cites W1973723330 @default.
• W4386229218 cites W1975046646 @default.
• W4386229218 cites W2003780050 @default.
• W4386229218 cites W2014225194 @default.
• W4386229218 cites W2014810690 @default.
• W4386229218 cites W2021244969 @default.
• W4386229218 cites W2024298957 @default.
• W4386229218 cites W2039222039 @default.
• W4386229218 cites W2039956699 @default.
• W4386229218 cites W2062297452 @default.
• W4386229218 cites W2063029924 @default.
• W4386229218 cites W2084842166 @default.
• W4386229218 cites W2085236616 @default.
• W4386229218 cites W2097569535 @default.
• W4386229218 cites W2100649970 @default.
• W4386229218 cites W2102278945 @default.
• W4386229218 cites W2125612801 @default.
• W4386229218 cites W2138207763 @default.
• W4386229218 cites W2149785020 @default.
• W4386229218 cites W2151564060 @default.
• W4386229218 cites W2179438025 @default.
• W4386229218 cites W2236591107 @default.
• W4386229218 cites W2626493603 @default.
• W4386229218 cites W2738677674 @default.
• W4386229218 cites W2794711502 @default.
• W4386229218 cites W2803922716 @default.
• W4386229218 cites W2896007774 @default.
• W4386229218 cites W2951924857 @default.
• W4386229218 cites W2953849385 @default.
• W4386229218 cites W2995868024 @default.
• W4386229218 cites W2999068325 @default.
• W4386229218 cites W3004978237 @default.
• W4386229218 cites W3006836706 @default.
• W4386229218 cites W3017590304 @default.
• W4386229218 cites W3047693408 @default.
• W4386229218 cites W3083608980 @default.
• W4386229218 cites W3119265336 @default.
• W4386229218 cites W3138861986 @default.
• W4386229218 cites W3158406147 @default.
• W4386229218 cites W3185211499 @default.
• W4386229218 cites W3191367133 @default.
• W4386229218 cites W3205588589 @default.
• W4386229218 cites W4248219898 @default.
• W4386229218 cites W4281959054 @default.
• W4386229218 cites W4286267878 @default.
• W4386229218 cites W4291396590 @default.
• W4386229218 cites W4292867658 @default.
• W4386229218 cites W4296406793 @default.
• W4386229218 cites W4297265272 @default.
• W4386229218 cites W4303438737 @default.
• W4386229218 cites W4307055245 @default.
• W4386229218 cites W4309432260 @default.
• W4386229218 cites W4310072730 @default.
• W4386229218 cites W4313368332 @default.
• W4386229218 cites W4362590507 @default.
• W4386229218 doi "https://doi.org/10.3390/ani13172717" @default.
• W4386229218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37684981" @default.
• W4386229218 hasPublicationYear "2023" @default.
• W4386229218 type Work @default.
• W4386229218 citedByCount "0" @default.
• W4386229218 crossrefType "journal-article" @default.
• W4386229218 hasAuthorship W4386229218A5006069022 @default.
• W4386229218 hasAuthorship W4386229218A5012937541 @default.
• W4386229218 hasAuthorship W4386229218A5015690491 @default.
• W4386229218 hasAuthorship W4386229218A5019595634 @default.
• W4386229218 hasAuthorship W4386229218A5027037635 @default.
• W4386229218 hasAuthorship W4386229218A5033367677 @default.
• W4386229218 hasAuthorship W4386229218A5049692788 @default.
• W4386229218 hasAuthorship W4386229218A5080308075 @default.
• W4386229218 hasAuthorship W4386229218A5083455588 @default.
• W4386229218 hasBestOaLocation W43862292181 @default.
• W4386229218 hasConcept C104317684 @default.
• W4386229218 hasConcept C127561419 @default.
• W4386229218 hasConcept C150194340 @default.
• W4386229218 hasConcept C162317418 @default.
• W4386229218 hasConcept C178790620 @default.
• W4386229218 hasConcept C185592680 @default.
• W4386229218 hasConcept C20904676 @default.
• W4386229218 hasConcept C2779018089 @default.
• W4386229218 hasConcept C540031477 @default.
• W4386229218 hasConcept C55493867 @default.
• W4386229218 hasConcept C62231903 @default.
• W4386229218 hasConcept C7836513 @default.

• next