FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386241952> ?p ?o ?g. }

• W4386241952 abstract "Rathor, Richa, Sukanya Srivastava, and Geetha Suryakumar. A comparative biochemical study between L-carnosine and β-alanine in amelioration of hypobaric hypoxia-induced skeletal muscle protein loss. High Alt Med Biol 00:000-000, 2023. Background: Carnosine (CAR; β-alanyl-L-histidine), a biologically active dipeptide is known for its unique pH-buffering capacity, metal chelating activity, and antioxidant and antiglycation property. β-Alanine (ALA) is a nonessential amino acid and used to enhance performance and cognitive functions. Hypobaric hypoxia (HH)-induced muscle protein loss is regulated by multifaceted signaling pathways. The present study investigated the beneficial effects of CAR and ALA against HH-associated muscle loss. Methodology: Simulated HH exposure was performed in an animal decompression chamber. Gastric oral administration of CAR (50 mg·kg-1) and ALA (450 mg·kg-1) were given daily for 3 days and at the end of the treatment, hindlimb skeletal muscle tissue was excised for western blot and biochemical assays. Results: Cosupplementation of CAR and ALA alone was able to ameliorate the hypoxia-induced inflammation, oxidative stress (FOXO), ER stress (GRP-78), and atrophic signaling (MuRF-1) in the skeletal muscles. Creatinine phospho kinase activity and apoptosis were also decreased in CAR- and ALA-supplemented rats. However, CAR showed enhanced protection in HH-induced muscle loss as CAR supplementation was able to enhance protein concentration, body weight, and decreased the protein oxidation and ALA administration was not able to restore the same. Conclusions: Hence, the present comprehensive study supports the fact that CAR (50 mg·kg-1) is more beneficial as compared with ALA (450 mg·kg-1) in ameliorating the hypoxia-induced skeletal muscle loss." @default.
• W4386241952 created "2023-08-30" @default.
• W4386241952 creator A5030439451 @default.
• W4386241952 creator A5030531796 @default.
• W4386241952 creator A5067057858 @default.
• W4386241952 date "2023-08-28" @default.
• W4386241952 modified "2023-09-30" @default.
• W4386241952 title "A Comparative Biochemical Study Between L-Carnosine and β-Alanine in Amelioration of Hypobaric Hypoxia-Induced Skeletal Muscle Protein Loss" @default.
• W4386241952 cites W1567614586 @default.
• W4386241952 cites W1590457525 @default.
• W4386241952 cites W1967673331 @default.
• W4386241952 cites W1988826900 @default.
• W4386241952 cites W2022693295 @default.
• W4386241952 cites W2042641359 @default.
• W4386241952 cites W2063576996 @default.
• W4386241952 cites W2078586688 @default.
• W4386241952 cites W2087648632 @default.
• W4386241952 cites W2090143261 @default.
• W4386241952 cites W2095264973 @default.
• W4386241952 cites W2111370164 @default.
• W4386241952 cites W2113762370 @default.
• W4386241952 cites W2120220697 @default.
• W4386241952 cites W2124243925 @default.
• W4386241952 cites W2137440027 @default.
• W4386241952 cites W2227751224 @default.
• W4386241952 cites W2244276231 @default.
• W4386241952 cites W2257963447 @default.
• W4386241952 cites W2285341117 @default.
• W4386241952 cites W2508267156 @default.
• W4386241952 cites W2599067217 @default.
• W4386241952 cites W2607199957 @default.
• W4386241952 cites W2745358338 @default.
• W4386241952 cites W2788309916 @default.
• W4386241952 cites W2890611412 @default.
• W4386241952 cites W2903363948 @default.
• W4386241952 cites W2945407775 @default.
• W4386241952 cites W3083813686 @default.
• W4386241952 cites W3083818123 @default.
• W4386241952 cites W3121032204 @default.
• W4386241952 cites W3142043422 @default.
• W4386241952 cites W3160022368 @default.
• W4386241952 cites W3196394008 @default.
• W4386241952 cites W4280491010 @default.
• W4386241952 cites W4283379473 @default.
• W4386241952 cites W4293084496 @default.
• W4386241952 cites W4296816736 @default.
• W4386241952 doi "https://doi.org/10.1089/ham.2023.0014" @default.
• W4386241952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37643283" @default.
• W4386241952 hasPublicationYear "2023" @default.
• W4386241952 type Work @default.
• W4386241952 citedByCount "0" @default.
• W4386241952 crossrefType "journal-article" @default.
• W4386241952 hasAuthorship W4386241952A5030439451 @default.
• W4386241952 hasAuthorship W4386241952A5030531796 @default.
• W4386241952 hasAuthorship W4386241952A5067057858 @default.
• W4386241952 hasConcept C126322002 @default.
• W4386241952 hasConcept C134018914 @default.
• W4386241952 hasConcept C178790620 @default.
• W4386241952 hasConcept C185592680 @default.
• W4386241952 hasConcept C2776151105 @default.
• W4386241952 hasConcept C2778004101 @default.
• W4386241952 hasConcept C2779856020 @default.
• W4386241952 hasConcept C2779959927 @default.
• W4386241952 hasConcept C2780687331 @default.
• W4386241952 hasConcept C515207424 @default.
• W4386241952 hasConcept C51738704 @default.
• W4386241952 hasConcept C540031477 @default.
• W4386241952 hasConcept C55493867 @default.
• W4386241952 hasConcept C71924100 @default.
• W4386241952 hasConcept C7836513 @default.
• W4386241952 hasConcept C98274493 @default.
• W4386241952 hasConceptScore W4386241952C126322002 @default.
• W4386241952 hasConceptScore W4386241952C134018914 @default.
• W4386241952 hasConceptScore W4386241952C178790620 @default.
• W4386241952 hasConceptScore W4386241952C185592680 @default.
• W4386241952 hasConceptScore W4386241952C2776151105 @default.
• W4386241952 hasConceptScore W4386241952C2778004101 @default.
• W4386241952 hasConceptScore W4386241952C2779856020 @default.
• W4386241952 hasConceptScore W4386241952C2779959927 @default.
• W4386241952 hasConceptScore W4386241952C2780687331 @default.
• W4386241952 hasConceptScore W4386241952C515207424 @default.
• W4386241952 hasConceptScore W4386241952C51738704 @default.
• W4386241952 hasConceptScore W4386241952C540031477 @default.
• W4386241952 hasConceptScore W4386241952C55493867 @default.
• W4386241952 hasConceptScore W4386241952C71924100 @default.
• W4386241952 hasConceptScore W4386241952C7836513 @default.
• W4386241952 hasConceptScore W4386241952C98274493 @default.
• W4386241952 hasLocation W43862419521 @default.
• W4386241952 hasLocation W43862419522 @default.
• W4386241952 hasOpenAccess W4386241952 @default.
• W4386241952 hasPrimaryLocation W43862419521 @default.
• W4386241952 hasRelatedWork W1974568996 @default.
• W4386241952 hasRelatedWork W2016840789 @default.
• W4386241952 hasRelatedWork W2048328229 @default.
• W4386241952 hasRelatedWork W2081376013 @default.
• W4386241952 hasRelatedWork W2099427598 @default.
• W4386241952 hasRelatedWork W2144576666 @default.
• W4386241952 hasRelatedWork W2309978229 @default.
• W4386241952 hasRelatedWork W2463478234 @default.
• W4386241952 hasRelatedWork W3032853368 @default.

• next