FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386248081> ?p ?o ?g. }

• W4386248081 abstract "Antecedentes y objetivo: los efectos adversos sistémicos son una de las principales limitaciones del uso de minoxidil oral a dosis bajas (MODB), especialmente en pacientes con hipertensión arterial o arritmias. El objetivo de este estudio fue evaluar la seguridad de MODB en estos pacientes. Material y método: estudio retrospectivo multicéntrico con pacientes con antecedentes de hipertensión o arritmias tratados con MODB para cualquier tipo de alopecia. Resultados: Se incluyó un total de 254 pacientes con hipertensión [176 mujeres (69,3%) y 78 hombres (30,7%)] con una edad media de 56,9 años (rango 19 – 82). La dosis de MODB se incrementó gradualmente en 128 pacientes, obteniendo un total de 382 dosis analizadas. Los pacientes estaban tomando de media 1,45 fármacos antihipertensivos (rango 0 – 5). Se detectaron EA sistémicos en 26 casos (6,8%), incluyendo mareo (3,1%), retención de líquidos (2,6%), malestar general (0,8%), taquicardia (0,8%) y cefalea (0,5%), requiriendo suspensión del MODB en 6 casos (1,5%). Los pacientes en tratamiento con doxazosina (P<0,001) o con tres o más antihipertensivos (P=0,012) presentaron mayor riesgo de suspensión de MODB. Conclusión: el tratamiento con MODB mostró un perfil de seguridad favorable en pacientes con hipertensión o arritmias, similar al de la población general. Background and Objective: Systemic adverse effects (AE) are a major concern of low-dose oral minoxidil (LDOM) treatment, especially in patients with arterial hypertension or arrhythmia. The objective of this study was to evaluate the safety of LDOM in patients with hypertension or arrhythmia. Patients and Methods: Retrospective multicenter study of patients with hypertension or arrhythmia treated with LDOM for any type of alopecia. Results: A total of 254 patients with hypertension [176 women (69.3%) and 78 men (30.7%)] with a mean age of 56.9 years (range 19-82) were included. From them, the dose of LDOM was titrated in 128 patients, allowing the analysis of 382 doses. Patients were receiving a mean of 1.45 (range 0 – 5) antihypertensive drugs. Systemic AE were detected in 26 cases (6.8%) and included lightheadedness (3.1%), fluid retention (2.6%), general malaise (0.8%), tachycardia (0.8%) and headache (0.5%), leading to LDOM discontinuation in 6 cases (1.5%). Prior treatment with doxazosin (P<0.001), or with three or more antihypertensive drugs (P=0.012) were associated with a higher risk of discontinuation of LDOM. Conclusions: LDOM treatment showed a favorable safety profile in patients with hypertension or arrhythmia, similar to general population." @default.
• W4386248081 created "2023-08-30" @default.
• W4386248081 creator A5003301290 @default.
• W4386248081 creator A5007241696 @default.
• W4386248081 creator A5009528683 @default.
• W4386248081 creator A5021906699 @default.
• W4386248081 creator A5024246047 @default.
• W4386248081 creator A5027385114 @default.
• W4386248081 creator A5040346605 @default.
• W4386248081 creator A5044072750 @default.
• W4386248081 creator A5059399104 @default.
• W4386248081 creator A5062405103 @default.
• W4386248081 creator A5064469850 @default.
• W4386248081 creator A5065377558 @default.
• W4386248081 creator A5068181002 @default.
• W4386248081 creator A5072724906 @default.
• W4386248081 creator A5073811537 @default.
• W4386248081 creator A5076293822 @default.
• W4386248081 creator A5086439694 @default.
• W4386248081 creator A5092815175 @default.
• W4386248081 date "2023-08-01" @default.
• W4386248081 modified "2023-10-03" @default.
• W4386248081 title "Seguridad de minoxidil oral a dosis bajas en pacientes con hipertensión o arritmias: estudio multicéntrico de 264 pacientes" @default.
• W4386248081 cites W2031951721 @default.
• W4386248081 cites W2045635893 @default.
• W4386248081 cites W2592012849 @default.
• W4386248081 cites W3047153462 @default.
• W4386248081 cites W3086270767 @default.
• W4386248081 cites W3087861580 @default.
• W4386248081 cites W3110542892 @default.
• W4386248081 cites W3132913155 @default.
• W4386248081 cites W3193823764 @default.
• W4386248081 cites W4280518051 @default.
• W4386248081 cites W4291222783 @default.
• W4386248081 doi "https://doi.org/10.1016/j.ad.2023.07.019" @default.
• W4386248081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37652097" @default.
• W4386248081 hasPublicationYear "2023" @default.
• W4386248081 type Work @default.
• W4386248081 citedByCount "0" @default.
• W4386248081 crossrefType "journal-article" @default.
• W4386248081 hasAuthorship W4386248081A5003301290 @default.
• W4386248081 hasAuthorship W4386248081A5007241696 @default.
• W4386248081 hasAuthorship W4386248081A5009528683 @default.
• W4386248081 hasAuthorship W4386248081A5021906699 @default.
• W4386248081 hasAuthorship W4386248081A5024246047 @default.
• W4386248081 hasAuthorship W4386248081A5027385114 @default.
• W4386248081 hasAuthorship W4386248081A5040346605 @default.
• W4386248081 hasAuthorship W4386248081A5044072750 @default.
• W4386248081 hasAuthorship W4386248081A5059399104 @default.
• W4386248081 hasAuthorship W4386248081A5062405103 @default.
• W4386248081 hasAuthorship W4386248081A5064469850 @default.
• W4386248081 hasAuthorship W4386248081A5065377558 @default.
• W4386248081 hasAuthorship W4386248081A5068181002 @default.
• W4386248081 hasAuthorship W4386248081A5072724906 @default.
• W4386248081 hasAuthorship W4386248081A5073811537 @default.
• W4386248081 hasAuthorship W4386248081A5076293822 @default.
• W4386248081 hasAuthorship W4386248081A5086439694 @default.
• W4386248081 hasAuthorship W4386248081A5092815175 @default.
• W4386248081 hasBestOaLocation W43862480811 @default.
• W4386248081 hasConcept C126322002 @default.
• W4386248081 hasConcept C197934379 @default.
• W4386248081 hasConcept C29456083 @default.
• W4386248081 hasConcept C71924100 @default.
• W4386248081 hasConceptScore W4386248081C126322002 @default.
• W4386248081 hasConceptScore W4386248081C197934379 @default.
• W4386248081 hasConceptScore W4386248081C29456083 @default.
• W4386248081 hasConceptScore W4386248081C71924100 @default.
• W4386248081 hasLocation W43862480811 @default.
• W4386248081 hasLocation W43862480812 @default.
• W4386248081 hasOpenAccess W4386248081 @default.
• W4386248081 hasPrimaryLocation W43862480811 @default.
• W4386248081 hasRelatedWork W1506200166 @default.
• W4386248081 hasRelatedWork W1995515455 @default.
• W4386248081 hasRelatedWork W2048182022 @default.
• W4386248081 hasRelatedWork W2080531066 @default.
• W4386248081 hasRelatedWork W2604872355 @default.
• W4386248081 hasRelatedWork W2748952813 @default.
• W4386248081 hasRelatedWork W2899084033 @default.
• W4386248081 hasRelatedWork W3031052312 @default.
• W4386248081 hasRelatedWork W3032375762 @default.
• W4386248081 hasRelatedWork W3108674512 @default.
• W4386248081 isParatext "false" @default.
• W4386248081 isRetracted "false" @default.
• W4386248081 workType "article" @default.