FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386254352> ?p ?o ?g. }

• W4386254352 abstract "Omalizumab, an anti-IgE monoclonal antibody, is an effective treatment in chronic spontaneous urticaria (CSU). Predictors of fast and good response for omalizumab treatment have not yet been identified and characterized.To evaluate whether soluble FcεRI (sFcεRI), a marker of IgE-mediated mast cell activation, predicts the time of response to omalizumab in CSU.Sera of 67 CSU patients were obtained before omalizumab treatment and analysed for sFcεRI levels by ELISA (2 ng/mL was used as cut-off for elevated sFcɛRI). Treatment response during the first 4 weeks was assessed with the urticaria activity score (UAS7), urticaria control test (UCT) and the rolling UAS7 (rUAS7).Elevated pre-treatment sFcɛRI levels were detected in more than 70% of patients with completely controlled disease (UCT = 16) and well-controlled disease (UCT = 12-15) and were significantly associated with disease control (χ2 = 4.94, p < 0.05). More than half of the patients (14/25) with low levels had poor disease control (UCT < 12). Of the patients who achieved complete and marked UAS7 response, respectively, 75% and 63% had elevated baseline sFcɛRI levels. Post-treatment UAS7 scores were lower in patients with elevated sFcɛRI levels reaching statistical significance at Week 3 (p < 0.05). Patients with elevated baseline sFcɛRI levels achieved rUAS7 ≤ 6 and = 0 earlier than those with lower levels (Days 9 vs. 13 and Days 12 vs. 14, respectively).Elevated sFcεRI serum levels predict early and good response to treatment with omalizumab, which may help to better design treatment options for CSU patients." @default.
• W4386254352 created "2023-08-30" @default.
• W4386254352 creator A5049788029 @default.
• W4386254352 creator A5055825874 @default.
• W4386254352 creator A5061963750 @default.
• W4386254352 creator A5063497748 @default.
• W4386254352 creator A5067167243 @default.
• W4386254352 creator A5083926014 @default.
• W4386254352 creator A5087745503 @default.
• W4386254352 creator A5089445189 @default.
• W4386254352 creator A5091156366 @default.
• W4386254352 date "2023-09-09" @default.
• W4386254352 modified "2023-10-03" @default.
• W4386254352 title "Elevated baseline soluble <scp>FcεRI</scp> may be linked to early response to omalizumab treatment in chronic spontaneous urticaria" @default.
• W4386254352 cites W1968667225 @default.
• W4386254352 cites W2037982270 @default.
• W4386254352 cites W2085255857 @default.
• W4386254352 cites W2115707856 @default.
• W4386254352 cites W2119522550 @default.
• W4386254352 cites W2121663010 @default.
• W4386254352 cites W2156152702 @default.
• W4386254352 cites W2216062768 @default.
• W4386254352 cites W2330047160 @default.
• W4386254352 cites W2555644081 @default.
• W4386254352 cites W2626673094 @default.
• W4386254352 cites W2765477066 @default.
• W4386254352 cites W2792525669 @default.
• W4386254352 cites W2794154574 @default.
• W4386254352 cites W2809444313 @default.
• W4386254352 cites W2883081495 @default.
• W4386254352 cites W2887855058 @default.
• W4386254352 cites W2901940756 @default.
• W4386254352 cites W2903336629 @default.
• W4386254352 cites W2912864571 @default.
• W4386254352 cites W2915033403 @default.
• W4386254352 cites W2951200598 @default.
• W4386254352 cites W2969808195 @default.
• W4386254352 cites W3005098770 @default.
• W4386254352 cites W3083341846 @default.
• W4386254352 cites W3107883827 @default.
• W4386254352 cites W3126817223 @default.
• W4386254352 cites W3135743637 @default.
• W4386254352 cites W3178726738 @default.
• W4386254352 cites W3200862524 @default.
• W4386254352 cites W3214646815 @default.
• W4386254352 cites W3216400601 @default.
• W4386254352 cites W4280492615 @default.
• W4386254352 cites W4283277641 @default.
• W4386254352 cites W4289028828 @default.
• W4386254352 cites W4289175142 @default.
• W4386254352 cites W4293072745 @default.
• W4386254352 cites W4294017754 @default.
• W4386254352 doi "https://doi.org/10.1111/jdv.19485" @default.
• W4386254352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37641982" @default.
• W4386254352 hasPublicationYear "2023" @default.
• W4386254352 type Work @default.
• W4386254352 citedByCount "0" @default.
• W4386254352 crossrefType "journal-article" @default.
• W4386254352 hasAuthorship W4386254352A5049788029 @default.
• W4386254352 hasAuthorship W4386254352A5055825874 @default.
• W4386254352 hasAuthorship W4386254352A5061963750 @default.
• W4386254352 hasAuthorship W4386254352A5063497748 @default.
• W4386254352 hasAuthorship W4386254352A5067167243 @default.
• W4386254352 hasAuthorship W4386254352A5083926014 @default.
• W4386254352 hasAuthorship W4386254352A5087745503 @default.
• W4386254352 hasAuthorship W4386254352A5089445189 @default.
• W4386254352 hasAuthorship W4386254352A5091156366 @default.
• W4386254352 hasBestOaLocation W43862543521 @default.
• W4386254352 hasConcept C126322002 @default.
• W4386254352 hasConcept C141105273 @default.
• W4386254352 hasConcept C159654299 @default.
• W4386254352 hasConcept C163864487 @default.
• W4386254352 hasConcept C203014093 @default.
• W4386254352 hasConcept C2778564945 @default.
• W4386254352 hasConcept C2779726688 @default.
• W4386254352 hasConcept C3017745231 @default.
• W4386254352 hasConcept C542903549 @default.
• W4386254352 hasConcept C71924100 @default.
• W4386254352 hasConcept C90924648 @default.
• W4386254352 hasConceptScore W4386254352C126322002 @default.
• W4386254352 hasConceptScore W4386254352C141105273 @default.
• W4386254352 hasConceptScore W4386254352C159654299 @default.
• W4386254352 hasConceptScore W4386254352C163864487 @default.
• W4386254352 hasConceptScore W4386254352C203014093 @default.
• W4386254352 hasConceptScore W4386254352C2778564945 @default.
• W4386254352 hasConceptScore W4386254352C2779726688 @default.
• W4386254352 hasConceptScore W4386254352C3017745231 @default.
• W4386254352 hasConceptScore W4386254352C542903549 @default.
• W4386254352 hasConceptScore W4386254352C71924100 @default.
• W4386254352 hasConceptScore W4386254352C90924648 @default.
• W4386254352 hasLocation W43862543521 @default.
• W4386254352 hasLocation W43862543522 @default.
• W4386254352 hasOpenAccess W4386254352 @default.
• W4386254352 hasPrimaryLocation W43862543521 @default.
• W4386254352 hasRelatedWork W12465354 @default.
• W4386254352 hasRelatedWork W1571696686 @default.
• W4386254352 hasRelatedWork W1978006696 @default.
• W4386254352 hasRelatedWork W2015379751 @default.
• W4386254352 hasRelatedWork W2026633984 @default.
• W4386254352 hasRelatedWork W2101202640 @default.

• next