FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386260928> ?p ?o ?g. }

• W4386260928 endingPage "S185" @default.
• W4386260928 startingPage "S185" @default.
• W4386260928 abstract "Abstract Introduction Hospitalized burn patients are at increased risk for venous thromboembolism (VTE). Clinical guidelines regarding thromboprophylaxis in burn patients with concomitant trauma are unclear. We aimed to compare the outcomes of early versus late thromboprophylaxis initiation for burn patients with concomitant trauma. Methods A 3-year analysis of 2017-2019 TQIP. We identified all adult burn patients with concomitant trauma who received thromboprophylaxis. We excluded patients that had severe TBI (Head AIS &gt; 2), were transferred, those that died &lt; 24 hours of admission and those that underwent hemorrhage control surgery. Patients were stratified based on the timing of initiation of postoperative thromboprophylaxis: Early (&lt; 24 hours of admission) versus Late ( &gt;24 hours). Multivariate regression analyses were performed. Outcome measures were odds of deep venous thrombosis (DVT), pulmonary embolism (PE), unplanned return to OR, unplanned ICU admission, post-prophylaxis PRBC transfusion and in-hospital mortality. Results 9,272 trauma patients with concomitant burns who received thromboprophylaxis were identified. Overall, mean age was 41.3 ± 13.4 years, 71.5% were male, and median ISS was 3 [1-8]. 53% had second degree burns, and 39% had more than 10% of total body surface area affected. Median time to thromboprophylaxis initiation was 11 [6-20.6] hours. On multivariate regression, patients who received thromboprophylaxis after 24 hours of admission had 1.8 times higher odds of developing DVT (aOR=1.8, 95% CI=1.04-3.11, p=0.03), 4.8 times higher odds of developing PE (aOR=4.8, 95% CI=1.9-11.9, p&lt;.001), 2 times higher odds of unplanned ICU admission (aOR=2.1, 95% CI=1.4-3.1, p&lt;0.001), and nonsignificant increase in the odds of unplanned return to OR (aOR=2, 95% CI=0.96-4.31, p=0.06). Further, early thromboprophylaxis was not associated with increased odds of post-prophylaxis PRBC transfusion (aOR=1.1, 95% CI=0.8-1.4, p=0.4), and in-hospital mortality (aOR=0.68, 95%CI=0.4-1.1, p=0.13) compared to patients who received late thromboprophylaxis. Conclusions Early VTE prophylaxis in burn patients is associated with decreased rates of DVT and PE, without increasing the risk of bleeding and mortality. VTE prophylaxis may be initiated within 24 hours of admission to reduce VTE in this high-risk patient population. Applicability of Research to Practice This work will guide the timing of initiation of venous thromboembolism prophylaxis in burn patients with concomitant trauma" @default.
• W4386260928 created "2023-08-30" @default.
• W4386260928 creator A5008589798 @default.
• W4386260928 creator A5017802623 @default.
• W4386260928 creator A5030635113 @default.
• W4386260928 creator A5057180342 @default.
• W4386260928 creator A5067747941 @default.
• W4386260928 creator A5068400454 @default.
• W4386260928 creator A5068527440 @default.
• W4386260928 creator A5069121713 @default.
• W4386260928 creator A5070494649 @default.
• W4386260928 creator A5082165690 @default.
• W4386260928 creator A5087534285 @default.
• W4386260928 date "2023-05-01" @default.
• W4386260928 modified "2023-10-18" @default.
• W4386260928 title "289 The Timing of Pharmacologic Venous Thromboembolism Prophylaxis Initiation for Burn Patients with Concomitant Trauma" @default.
• W4386260928 doi "https://doi.org/10.1093/jbcr/irad045.264" @default.
• W4386260928 hasPublicationYear "2023" @default.
• W4386260928 type Work @default.
• W4386260928 citedByCount "0" @default.
• W4386260928 crossrefType "journal-article" @default.
• W4386260928 hasAuthorship W4386260928A5008589798 @default.
• W4386260928 hasAuthorship W4386260928A5017802623 @default.
• W4386260928 hasAuthorship W4386260928A5030635113 @default.
• W4386260928 hasAuthorship W4386260928A5057180342 @default.
• W4386260928 hasAuthorship W4386260928A5067747941 @default.
• W4386260928 hasAuthorship W4386260928A5068400454 @default.
• W4386260928 hasAuthorship W4386260928A5068527440 @default.
• W4386260928 hasAuthorship W4386260928A5069121713 @default.
• W4386260928 hasAuthorship W4386260928A5070494649 @default.
• W4386260928 hasAuthorship W4386260928A5082165690 @default.
• W4386260928 hasAuthorship W4386260928A5087534285 @default.
• W4386260928 hasBestOaLocation W43862609281 @default.
• W4386260928 hasConcept C126322002 @default.
• W4386260928 hasConcept C141071460 @default.
• W4386260928 hasConcept C156957248 @default.
• W4386260928 hasConcept C2776265017 @default.
• W4386260928 hasConcept C2776782833 @default.
• W4386260928 hasConcept C2779384505 @default.
• W4386260928 hasConcept C2780011451 @default.
• W4386260928 hasConcept C2780868729 @default.
• W4386260928 hasConcept C42219234 @default.
• W4386260928 hasConcept C71924100 @default.
• W4386260928 hasConceptScore W4386260928C126322002 @default.
• W4386260928 hasConceptScore W4386260928C141071460 @default.
• W4386260928 hasConceptScore W4386260928C156957248 @default.
• W4386260928 hasConceptScore W4386260928C2776265017 @default.
• W4386260928 hasConceptScore W4386260928C2776782833 @default.
• W4386260928 hasConceptScore W4386260928C2779384505 @default.
• W4386260928 hasConceptScore W4386260928C2780011451 @default.
• W4386260928 hasConceptScore W4386260928C2780868729 @default.
• W4386260928 hasConceptScore W4386260928C42219234 @default.
• W4386260928 hasConceptScore W4386260928C71924100 @default.
• W4386260928 hasIssue "Supplement_2" @default.
• W4386260928 hasLocation W43862609281 @default.
• W4386260928 hasOpenAccess W4386260928 @default.
• W4386260928 hasPrimaryLocation W43862609281 @default.
• W4386260928 hasRelatedWork W1965433139 @default.
• W4386260928 hasRelatedWork W2037999426 @default.
• W4386260928 hasRelatedWork W2289259276 @default.
• W4386260928 hasRelatedWork W2733738974 @default.
• W4386260928 hasRelatedWork W2790885812 @default.
• W4386260928 hasRelatedWork W2981730791 @default.
• W4386260928 hasRelatedWork W3111527613 @default.
• W4386260928 hasRelatedWork W4231905262 @default.
• W4386260928 hasRelatedWork W4232182304 @default.
• W4386260928 hasRelatedWork W4324007940 @default.
• W4386260928 hasVolume "44" @default.
• W4386260928 isParatext "false" @default.
• W4386260928 isRetracted "false" @default.
• W4386260928 workType "article" @default.