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• W4386272016 abstract "Abstract Although there are numerous benefits to diagnostic prenatal testing, such as fetal exome sequencing, there are also consequences, including the possibility of receiving variants of uncertain significance or identifying secondary findings. In this study, we utilized a survey‐based discrete choice experiment to elicit the preferences of pregnant people in Northern California for hypothetical prenatal genomic tests. Pregnant individuals were invited to complete the survey through advertisements on social media. Five test attributes were studied: likelihood of getting a result, time taken to receive results, who explains results, reporting of uncertain results, and reporting of secondary findings. The survey also gathered information about the participants' demographics, current and past pregnancies, and tolerance of uncertainty using the IUS‐12 scale. Participants were eligible if they were female, currently 24 or more weeks pregnant, and able to read/write enough English or Spanish to complete an online survey. Overall, participants ( n = 56) preferred the option of having a prenatal test over not having a prenatal test ( p < 0.01) and had substantially higher preferences for tests with the highest likelihood of getting a result ( p < 0.01). There were also positive preferences for tests that reported secondary findings ( p = 0.01) and those where results were returned by a genetic specialist (vs. their prenatal provider) ( p = 0.04). These findings can be used to guide conversations between pregnant individuals and genetics specialists, such as genetic counselors, as they weigh the pros and cons of diagnostic prenatal testing options." @default.
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• W4386272016 date "2023-08-30" @default.
• W4386272016 modified "2023-09-30" @default.
• W4386272016 title "Exploring prenatal testing preferences among <scp>US</scp> pregnant individuals: A discrete choice experiment" @default.
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• W4386272016 doi "https://doi.org/10.1002/jgc4.1777" @default.
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