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• W4386272514 abstract "Summary Poor sleep quality or sleep deprivation may be related to decreased bone mineral density. We aimed to assess whether associations of sleep characteristics and bone turnover or strength are present in adults from the general population and whether these are independent of common risk factors such as sex, age, and obesity. A total of 1037 participants from the Study of Health in Pomerania‐TREND underwent laboratory‐based polysomnography and quantitative ultrasound measurements at the heel. Of these participants, 804 completed standardised questionnaires to assess daytime sleepiness, insomnia, and sleep quality. Serum concentrations of two bone turnover markers, intact amino‐terminal propeptide of type 1 procollagen (P1NP) and carboxy‐terminal telopeptide of type 1 collagen (CTX) were measured. Cross‐sectional associations of polysomnography variables (total sleep time, sleep efficiency, time spent wake after sleep onset, oxygen desaturation index, apnea–hypopnea index, and obstructive sleep apnea [OSA]), as well as sleep questionnaire scores with the bone turnover markers and the ultrasound‐based stiffness index were assessed in linear regression models. In adjusted models, higher insomnia scores and lower sleep quality scores were related to a higher bone turnover in women but not in men. However, associations between polysomnography variables or questionnaire scores and the stiffness index were absent. Our study provides limited evidence for relationships between sleep characteristics and bone turnover and strength independent of common risk factors for OSA and osteoporosis. Nevertheless, women reporting poor sleep or insomnia in combination with risk factors for osteoporosis might benefit from an evaluation of bone health." @default.
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• W4386272514 date "2023-08-30" @default.
• W4386272514 modified "2023-10-16" @default.
• W4386272514 title "Sleep characteristics and parameters of bone turnover and strength in the adult population: results from the Study of Health in <scp>Pomerania‐TREND</scp>" @default.
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• W4386272514 doi "https://doi.org/10.1111/jsr.14019" @default.
• W4386272514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37646341" @default.
• W4386272514 hasPublicationYear "2023" @default.
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