Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386283055> ?p ?o ?g. }
- W4386283055 endingPage "1475" @default.
- W4386283055 startingPage "1475" @default.
- W4386283055 abstract "Background: Hirschsprung disease (HD) is characterized by absent neuronal innervation of the distal colonic bowel wall and is surgically treated by removing the affected bowel segment via pull-through surgery (PT). Incomplete removal of the affected segment is called transition zone anastomosis (TZA). The current systematic review aims to provide a comprehensive overview of the prevalence and clinical impact of TZA. Methods: Pubmed, Embase, Cinahl, and Web of Sciences were searched (last search: October 2020), and studies describing histopathological examination for TZA in patients with HD were included. Data were synthesized into aggregated Event Rates (ER) of TZA using random-effects meta-analysis. The clinical impact was defined in terms of obstructive defecation problems, enterocolitis, soiling, incontinence, and the need for additional surgical procedures. The quality of studies was assessed using the Newcastle–Ottawa Scale. Key Results: This systematic review included 34 studies, representing 2207 patients. After excluding series composed of only patients undergoing redo PT, the prevalence was 9% (ER = 0.09, 95% CI = 0.05–0.14, p < 0.001, I2 = 86%). TZA occurred more often after operation techniques other than Duhamel (X2 = 19.21, p = <0.001). Patients with TZA often had obstructive defecation problems (62%), enterocolitis (38%), soiling (28%), and fecal incontinence (24%) in follow-up periods ranging from 6 months to 13 years. Patients with TZA more often had persistent obstructive symptoms (X2 = 7.26, p = 0.007). Conclusions and Inferences: TZA is associated with obstructive defecation problems and redo PT and is thus necessary to prevent." @default.
- W4386283055 created "2023-08-31" @default.
- W4386283055 creator A5007334212 @default.
- W4386283055 creator A5009303794 @default.
- W4386283055 creator A5010364628 @default.
- W4386283055 creator A5028672801 @default.
- W4386283055 creator A5049526268 @default.
- W4386283055 creator A5057312498 @default.
- W4386283055 date "2023-08-30" @default.
- W4386283055 modified "2023-10-17" @default.
- W4386283055 title "The Prevalence and Clinical Impact of Transition Zone Anastomosis in Hirschsprung Disease: A Systematic Review and Meta-Analysis" @default.
- W4386283055 cites W1512727380 @default.
- W4386283055 cites W1968234515 @default.
- W4386283055 cites W1981546257 @default.
- W4386283055 cites W1982971311 @default.
- W4386283055 cites W1985617760 @default.
- W4386283055 cites W1986776455 @default.
- W4386283055 cites W1988759864 @default.
- W4386283055 cites W1990761159 @default.
- W4386283055 cites W1993075742 @default.
- W4386283055 cites W1994189350 @default.
- W4386283055 cites W2005453797 @default.
- W4386283055 cites W2006983437 @default.
- W4386283055 cites W2013073711 @default.
- W4386283055 cites W2013653947 @default.
- W4386283055 cites W2015784553 @default.
- W4386283055 cites W2018151227 @default.
- W4386283055 cites W2023425390 @default.
- W4386283055 cites W2023665735 @default.
- W4386283055 cites W2024571518 @default.
- W4386283055 cites W2032327339 @default.
- W4386283055 cites W2033693511 @default.
- W4386283055 cites W2033993891 @default.
- W4386283055 cites W2038886321 @default.
- W4386283055 cites W2039053659 @default.
- W4386283055 cites W2051851860 @default.
- W4386283055 cites W2052948630 @default.
- W4386283055 cites W2053104366 @default.
- W4386283055 cites W2056022364 @default.
- W4386283055 cites W2067563970 @default.
- W4386283055 cites W2075222910 @default.
- W4386283055 cites W2079963095 @default.
- W4386283055 cites W2081519092 @default.
- W4386283055 cites W2083189976 @default.
- W4386283055 cites W2092584782 @default.
- W4386283055 cites W2102345531 @default.
- W4386283055 cites W2105363703 @default.
- W4386283055 cites W2114612364 @default.
- W4386283055 cites W2126930838 @default.
- W4386283055 cites W2127777039 @default.
- W4386283055 cites W2150887006 @default.
- W4386283055 cites W2156098321 @default.
- W4386283055 cites W2157823046 @default.
- W4386283055 cites W2323541158 @default.
- W4386283055 cites W2407178076 @default.
- W4386283055 cites W2467288229 @default.
- W4386283055 cites W2507724550 @default.
- W4386283055 cites W2516974793 @default.
- W4386283055 cites W2521210423 @default.
- W4386283055 cites W2560438049 @default.
- W4386283055 cites W2585470529 @default.
- W4386283055 cites W2587656474 @default.
- W4386283055 cites W2743015946 @default.
- W4386283055 cites W2757376021 @default.
- W4386283055 cites W2781581721 @default.
- W4386283055 cites W2885767790 @default.
- W4386283055 cites W2900570579 @default.
- W4386283055 cites W2903966467 @default.
- W4386283055 cites W2904394861 @default.
- W4386283055 cites W2982255564 @default.
- W4386283055 cites W2989864550 @default.
- W4386283055 cites W2990456897 @default.
- W4386283055 cites W2991792334 @default.
- W4386283055 cites W3012673419 @default.
- W4386283055 cites W3029932535 @default.
- W4386283055 cites W3045738738 @default.
- W4386283055 cites W4243525378 @default.
- W4386283055 cites W4254697963 @default.
- W4386283055 doi "https://doi.org/10.3390/children10091475" @default.
- W4386283055 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37761437" @default.
- W4386283055 hasPublicationYear "2023" @default.
- W4386283055 type Work @default.
- W4386283055 citedByCount "0" @default.
- W4386283055 crossrefType "journal-article" @default.
- W4386283055 hasAuthorship W4386283055A5007334212 @default.
- W4386283055 hasAuthorship W4386283055A5009303794 @default.
- W4386283055 hasAuthorship W4386283055A5010364628 @default.
- W4386283055 hasAuthorship W4386283055A5028672801 @default.
- W4386283055 hasAuthorship W4386283055A5049526268 @default.
- W4386283055 hasAuthorship W4386283055A5057312498 @default.
- W4386283055 hasBestOaLocation W43862830551 @default.
- W4386283055 hasConcept C108797546 @default.
- W4386283055 hasConcept C126322002 @default.
- W4386283055 hasConcept C141071460 @default.
- W4386283055 hasConcept C71924100 @default.
- W4386283055 hasConcept C8443397 @default.
- W4386283055 hasConcept C90924648 @default.
- W4386283055 hasConcept C95190672 @default.