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- W4386302361 abstract "We present a stochastic framework to decipher fluctuations propagation in classes of coherent feed-forward loops. The systematic contribution of the direct (one-step) and indirect (two-step) pathways is considered to quantify fluctuations of the output node. We also consider both additive and multiplicative integration mechanisms of the two parallel pathways (one-step and two-step). Analytical expression of the output node's coefficient of variation shows contributions of intrinsic, one-step, two-step, and cross-interaction in closed form. We observe a diverse range of degeneracy and non-degeneracy in each of the decomposed fluctuations term and their contribution to the overall output fluctuations of each coherent feed-forward loop motif. Analysis of output fluctuations reveals a maximal level of fluctuations of the coherent feed-forward loop motif of type 1." @default.
- W4386302361 created "2023-08-31" @default.
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- W4386302361 date "2023-08-29" @default.
- W4386302361 modified "2023-09-27" @default.
- W4386302361 title "Interplay of degeneracy and non-degeneracy in fluctuations propagation in coherent feed-forward loop motif" @default.
- W4386302361 doi "https://doi.org/10.48550/arxiv.2308.15025" @default.
- W4386302361 hasPublicationYear "2023" @default.
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