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- W4386308045 endingPage "13513" @default.
- W4386308045 startingPage "13513" @default.
- W4386308045 abstract "A significant clinical association between osteoporosis (OP) and fibromyalgia (FM) has been shown in the literature. Given the need for specific biomarkers to improve OP and FM management, common miRNAs might provide promising tracks for future prevention and treatment. The aim of this review is to identify miRNAs described in OP and FM, and dysregulated in the same direction in both pathologies. The PubMed database was searched until June 2023, with a clear mention of OP, FM, and miRNA expression. Clinical trials, case–control, and cross-sectional studies were included. Gray literature was not searched. Out of the 184 miRNAs found in our research, 23 are shared by OP and FM: 7 common miRNAs are dysregulated in the same direction for both pathologies (3 up-, 4 downregulated). The majority of these common miRNAs are involved in the Wnt pathway and the cholinergic system and a possible link has been highlighted. Further studies are needed to explore this relationship. Moreover, the harmonization of technical methods is necessary to confirm miRNAs shared between OP and FM." @default.
- W4386308045 created "2023-09-01" @default.
- W4386308045 creator A5044069348 @default.
- W4386308045 creator A5047119503 @default.
- W4386308045 creator A5058324912 @default.
- W4386308045 creator A5077272373 @default.
- W4386308045 creator A5092721888 @default.
- W4386308045 date "2023-08-31" @default.
- W4386308045 modified "2023-09-27" @default.
- W4386308045 title "Common miRNAs of Osteoporosis and Fibromyalgia: A Review" @default.
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