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- W4386315860 abstract "Abstract Background Obsessive-compulsive disorder (OCD) is one of the most common psychiatric diagnoses in the world. Common evidence-based treatments for OCD are pharmacotherapy and psychotherapy. Aims To examine cognitive behavior therapy (CBT) with and without pharmacotherapy for treating of OCD. Methods Participants were 40 adults between 18 and 70 years, recruited through self-referrals, professional and clinic referrals, and hospital advertisements. Participants diagnosed with OCD through telephone screening were referred to Sina Hospital in Hamadan City, Iran, for further assessment. Results Of 40 participants (Most patients were women 80%, with university education 57.5%, and between 31 and 65 years old 65%), 20 parcipitants received CBT and 20 underwent CBT plus sertraline. After completing the intervention in both conditions, the mean OCD symptom severity score on the Y-BOCS decreased (P < 0.001), indicating that OCD symptoms improved in both conditions. The results showed that the reduction of OCD in each group was significant compared to the beginning of the study, but the two groups did not differ significantly (P = 0.058). The variables of gender, comorbidity, personality, education, and initial severity of the disease did not interact with treatment in the two treatment groups. Conclusions Based on the findings of the present study, the addition of drug therapy to CBT in patients with OCD was not associated with increased therapeutic response, indicating the high effectiveness of CBT in the treatment of OCD." @default.
- W4386315860 created "2023-09-01" @default.
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- W4386315860 date "2023-08-31" @default.
- W4386315860 modified "2023-09-27" @default.
- W4386315860 title "The effectiveness of Cognitive-Behavioral Therapy with and without Sertraline in patients with Obsessive-Compulsive Disorder: a pilot randomized trial" @default.
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- W4386315860 doi "https://doi.org/10.21203/rs.3.rs-3205058/v1" @default.
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