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- W4386317063 abstract "Neurogastroenterology is the study of neurology in the gastrointestinal tract, liver, gallbladder, and pancreas involving interactions between, and the integration of the enteric nervous system and the central nervous system. The GI microbiota impact brain development, the host immune system, emotion, and behavior. Molecular interactions that occur between the GI microbiome and its metabolome with the host's central nervous system are recognized as complex, bidirectional, and may involve endocrine, neuronal, toll-like receptors, and metabolite-dependent pathways. This bidirectional communication is vital for maintaining normal brain function and gastrointestinal homeostasis. Crosstalk between the gut and brain when there is perturbation or disruption in the communication axis can result in psychological and neurological disorders. Additionally, bacterial translocation due to intestinal barrier dysfunction results in neuroactive metabolites and other microbiota components that induce a neuroinflammatory response in the brain." @default.
- W4386317063 created "2023-09-01" @default.
- W4386317063 date "2023-08-31" @default.
- W4386317063 modified "2023-10-01" @default.
- W4386317063 title "Neurological Interactions with Microbiomes" @default.
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- W4386317063 doi "https://doi.org/10.1002/9781119862611.ch16" @default.
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