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• W4386325428 endingPage "2253" @default.
• W4386325428 startingPage "2253" @default.
• W4386325428 abstract "Biofilms are responsible for the most prevalent oral infections such as caries, periodontal disease, and pulp and periapical lesions, which affect the quality of life of people. Antibiotics have been widely used to treat these conditions as therapeutic and prophylactic compounds. However, due to the emergence of microbial resistance to antibiotics, there is an urgent need to develop and evaluate new antimicrobial agents. This scoping review offers an extensive and detailed synthesis of the potential role of selenium nanoparticles (SeNPs) in combating oral pathogens responsible for causing infectious diseases. A systematic search was conducted up until May 2022, encompassing the MEDLINE, Embase, Scopus, and Lilacs databases. We included studies focused on evaluating the antimicrobial efficacy of SeNPs on planktonic and biofilm forms and their side effects in in vitro studies. The selection process and data extraction were carried out by two researchers independently. A qualitative synthesis of the results was performed. A total of twenty-two articles were considered eligible for this scoping review. Most of the studies reported relevant antimicrobial efficacy against C. albicans, S. mutans, E. faecalis, and P. gingivalis, as well as effective antioxidant activity and limited toxicity. Further research is mandatory to critically assess the effectiveness of this alternative treatment in ex vivo and in vivo settings, with detailed information about SeNPs concentrations employed, their physicochemical properties, and the experimental conditions to provide enough evidence to address the construction and development of well-designed and safe protocols." @default.
• W4386325428 created "2023-09-01" @default.
• W4386325428 creator A5022919675 @default.
• W4386325428 creator A5033203874 @default.
• W4386325428 creator A5050815650 @default.
• W4386325428 creator A5059369578 @default.
• W4386325428 creator A5067438292 @default.
• W4386325428 creator A5084851279 @default.
• W4386325428 creator A5088911569 @default.
• W4386325428 date "2023-08-31" @default.
• W4386325428 modified "2023-10-17" @default.
• W4386325428 title "Antimicrobial Activity of Selenium Nanoparticles (SeNPs) against Potentially Pathogenic Oral Microorganisms: A Scoping Review" @default.
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