FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386327979> ?p ?o ?g. }

• W4386327979 abstract "Background: Cold exposure (CE) can effectively modulate adipose tissue metabolism and improve metabolic health. Although previous metabolomics studies have primarily focused on analyzing one or two samples from serum, brown adipose tissue (BAT), white adipose tissue (WAT), and liver samples, there is a significant lack of simultaneous analysis of multiple tissues regarding the metabolic changes induced by CE in mice. Therefore, our study aims to investigate the metabolic profiles of the major tissues involved. Methods: A total of 14 male C57BL/6J mice were randomly assigned to two groups: the control group ( n = 7) and the CE group ( n = 7). Metabolite determination was carried out using gas chromatography-mass spectrometry (GC-MS), and multivariate analysis was employed to identify metabolites exhibiting differential expression between the two groups. Results: In our study, we identified 32 discriminant metabolites in BAT, 17 in WAT, 21 in serum, 7 in the liver, 16 in the spleen, and 26 in the kidney, respectively. Among these metabolites, amino acids, fatty acids, and nucleotides emerged as the most significantly altered compounds. These metabolites were found to be associated with 12 differential metabolic pathways closely related to amino acids, fatty acids, and energy metabolism. Conclusion: Our study may provide valuable insights into the metabolic effects induced by CE, and they have the potential to inspire novel approaches for treating metabolic diseases." @default.
• W4386327979 created "2023-09-01" @default.
• W4386327979 creator A5004718466 @default.
• W4386327979 creator A5006019048 @default.
• W4386327979 creator A5020383307 @default.
• W4386327979 creator A5033476823 @default.
• W4386327979 creator A5033747658 @default.
• W4386327979 creator A5043241104 @default.
• W4386327979 creator A5055145179 @default.
• W4386327979 creator A5058175379 @default.
• W4386327979 creator A5061939957 @default.
• W4386327979 creator A5067471551 @default.
• W4386327979 date "2023-08-31" @default.
• W4386327979 modified "2023-10-01" @default.
• W4386327979 title "Assessment of cold exposure-induced metabolic changes in mice using untargeted metabolomics" @default.
• W4386327979 cites W1127264686 @default.
• W4386327979 cites W1687167322 @default.
• W4386327979 cites W1921869568 @default.
• W4386327979 cites W1965079305 @default.
• W4386327979 cites W1976177239 @default.
• W4386327979 cites W1980593740 @default.
• W4386327979 cites W1982766384 @default.
• W4386327979 cites W1986602268 @default.
• W4386327979 cites W1996195892 @default.
• W4386327979 cites W2005827500 @default.
• W4386327979 cites W2013807797 @default.
• W4386327979 cites W2013891116 @default.
• W4386327979 cites W2017771330 @default.
• W4386327979 cites W2020247728 @default.
• W4386327979 cites W2032149290 @default.
• W4386327979 cites W2040328785 @default.
• W4386327979 cites W2058989758 @default.
• W4386327979 cites W2060813891 @default.
• W4386327979 cites W2062600479 @default.
• W4386327979 cites W2066768557 @default.
• W4386327979 cites W2070892520 @default.
• W4386327979 cites W2077132863 @default.
• W4386327979 cites W2089210920 @default.
• W4386327979 cites W2101117598 @default.
• W4386327979 cites W2112331117 @default.
• W4386327979 cites W2112520822 @default.
• W4386327979 cites W2118708320 @default.
• W4386327979 cites W2122367003 @default.
• W4386327979 cites W2123102900 @default.
• W4386327979 cites W2132358997 @default.
• W4386327979 cites W2132596222 @default.
• W4386327979 cites W2144057578 @default.
• W4386327979 cites W2145142659 @default.
• W4386327979 cites W2150590213 @default.
• W4386327979 cites W2151539027 @default.
• W4386327979 cites W2153081066 @default.
• W4386327979 cites W2162023168 @default.
• W4386327979 cites W2167372092 @default.
• W4386327979 cites W2170414800 @default.
• W4386327979 cites W2171537806 @default.
• W4386327979 cites W2196793559 @default.
• W4386327979 cites W2208785046 @default.
• W4386327979 cites W2296257971 @default.
• W4386327979 cites W2318465668 @default.
• W4386327979 cites W2318648257 @default.
• W4386327979 cites W2332777704 @default.
• W4386327979 cites W2403047053 @default.
• W4386327979 cites W2414232855 @default.
• W4386327979 cites W2557431621 @default.
• W4386327979 cites W2587843052 @default.
• W4386327979 cites W2606498025 @default.
• W4386327979 cites W2611486163 @default.
• W4386327979 cites W2624029503 @default.
• W4386327979 cites W2625485505 @default.
• W4386327979 cites W2755296400 @default.
• W4386327979 cites W2765303057 @default.
• W4386327979 cites W2788781113 @default.
• W4386327979 cites W2788974968 @default.
• W4386327979 cites W2797100077 @default.
• W4386327979 cites W2800592928 @default.
• W4386327979 cites W2801170851 @default.
• W4386327979 cites W2902246840 @default.
• W4386327979 cites W2939616681 @default.
• W4386327979 cites W2969705160 @default.
• W4386327979 cites W2971039710 @default.
• W4386327979 cites W3005421475 @default.
• W4386327979 cites W3016355214 @default.
• W4386327979 cites W3043821164 @default.
• W4386327979 cites W3092329433 @default.
• W4386327979 cites W3092964366 @default.
• W4386327979 cites W3109142988 @default.
• W4386327979 cites W3120832178 @default.
• W4386327979 cites W3123822507 @default.
• W4386327979 cites W3135107328 @default.
• W4386327979 cites W3156651346 @default.
• W4386327979 cites W3164882939 @default.
• W4386327979 cites W31735925 @default.
• W4386327979 cites W3193849134 @default.
• W4386327979 cites W3200426977 @default.
• W4386327979 cites W3204028938 @default.
• W4386327979 cites W3209772190 @default.
• W4386327979 cites W4223470127 @default.
• W4386327979 cites W4226173445 @default.
• W4386327979 cites W4229032525 @default.
• W4386327979 cites W4280509959 @default.

• next