FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386329692> ?p ?o ?g. }

• W4386329692 abstract "The bed nucleus of the stria terminalis (BNST), as part of the extended amygdala, has become a region of increasing interest regarding its role in numerous human stress-related psychiatric diseases, including post-traumatic stress disorder and generalized anxiety disorder amongst others. The BNST is a sexually dimorphic and highly complex structure as already evident by its anatomy consisting of 11 to 18 distinct sub-nuclei in rodents. Located in the ventral forebrain, the BNST is anatomically and functionally connected to many other limbic structures, including the amygdala, hypothalamic nuclei, basal ganglia, and hippocampus. Given this extensive connectivity, the BNST is thought to play a central and critical role in the integration of information on hedonic-valence, mood, arousal states, processing emotional information, and in general shape motivated and stress/anxiety-related behavior. Regarding its role in regulating stress and anxiety behavior the anterolateral group of the BNST (BNSTALG) has been extensively studied and contains a wide variety of neurons that differ in their electrophysiological properties, morphology, spatial organization, neuropeptidergic content and input and output synaptic organization which shape their activity and function. In addition to this great diversity, further species-specific differences are evident on multiple levels. For example, classic studies performed in adult rat brain identified three distinct neuron types (Type I-III) based on their electrophysiological properties and ion channel expression. Whilst similar neurons have been identified in other animal species, such as mice and non-human primates such as macaques, cross-species comparisons have revealed intriguing differences such as their comparative prevalence in the BNSTALG as well as their electrophysiological and morphological properties, amongst other differences. Given this tremendous complexity on multiple levels, the comprehensive elucidation of the BNSTALG circuitry and its role in regulating stress/anxiety-related behavior is a major challenge. In the present Review we bring together and highlight the key differences in BNSTALG structure, functional connectivity, the electrophysiological and morphological properties, and neuropeptidergic profiles of BNSTALG neurons between species with the aim to facilitate future studies of this important nucleus in relation to human disease." @default.
• W4386329692 created "2023-09-01" @default.
• W4386329692 creator A5070952959 @default.
• W4386329692 creator A5092725025 @default.
• W4386329692 creator A5092725026 @default.
• W4386329692 date "2023-08-30" @default.
• W4386329692 modified "2023-10-01" @default.
• W4386329692 title "The neurophysiological basis of stress and anxiety - comparing neuronal diversity in the bed nucleus of the stria terminalis (BNST) across species" @default.
• W4386329692 cites W104100557 @default.
• W4386329692 cites W104981233 @default.
• W4386329692 cites W1439188128 @default.
• W4386329692 cites W1494369493 @default.
• W4386329692 cites W1658218205 @default.
• W4386329692 cites W1966489889 @default.
• W4386329692 cites W1970321055 @default.
• W4386329692 cites W1970713268 @default.
• W4386329692 cites W1971994650 @default.
• W4386329692 cites W1972489844 @default.
• W4386329692 cites W1973438804 @default.
• W4386329692 cites W1977521403 @default.
• W4386329692 cites W1978471994 @default.
• W4386329692 cites W1980267862 @default.
• W4386329692 cites W1980560572 @default.
• W4386329692 cites W1981069634 @default.
• W4386329692 cites W1986550451 @default.
• W4386329692 cites W1989713715 @default.
• W4386329692 cites W1999063101 @default.
• W4386329692 cites W2003982930 @default.
• W4386329692 cites W2005074550 @default.
• W4386329692 cites W2006421350 @default.
• W4386329692 cites W2006516339 @default.
• W4386329692 cites W2007567221 @default.
• W4386329692 cites W2008014693 @default.
• W4386329692 cites W2008192007 @default.
• W4386329692 cites W2008280777 @default.
• W4386329692 cites W2008868341 @default.
• W4386329692 cites W2010638458 @default.
• W4386329692 cites W2011856338 @default.
• W4386329692 cites W2012367545 @default.
• W4386329692 cites W2012940067 @default.
• W4386329692 cites W2014232238 @default.
• W4386329692 cites W2017507322 @default.
• W4386329692 cites W2018843451 @default.
• W4386329692 cites W2019584232 @default.
• W4386329692 cites W2021178076 @default.
• W4386329692 cites W2023443471 @default.
• W4386329692 cites W2025772353 @default.
• W4386329692 cites W2025997572 @default.
• W4386329692 cites W2027209262 @default.
• W4386329692 cites W2027289999 @default.
• W4386329692 cites W2029947470 @default.
• W4386329692 cites W2033137859 @default.
• W4386329692 cites W2034228917 @default.
• W4386329692 cites W2034509888 @default.
• W4386329692 cites W2034603599 @default.
• W4386329692 cites W2035407079 @default.
• W4386329692 cites W2036185559 @default.
• W4386329692 cites W2037940663 @default.
• W4386329692 cites W2038159735 @default.
• W4386329692 cites W2038738726 @default.
• W4386329692 cites W2039020023 @default.
• W4386329692 cites W2041736210 @default.
• W4386329692 cites W2041958212 @default.
• W4386329692 cites W2042383818 @default.
• W4386329692 cites W2042824787 @default.
• W4386329692 cites W2043534501 @default.
• W4386329692 cites W2044196172 @default.
• W4386329692 cites W2044431563 @default.
• W4386329692 cites W2044542417 @default.
• W4386329692 cites W2044857185 @default.
• W4386329692 cites W2047276581 @default.
• W4386329692 cites W2051741307 @default.
• W4386329692 cites W2053807193 @default.
• W4386329692 cites W2055298542 @default.
• W4386329692 cites W2055490134 @default.
• W4386329692 cites W2058489480 @default.
• W4386329692 cites W2058670670 @default.
• W4386329692 cites W2061478482 @default.
• W4386329692 cites W2062106032 @default.
• W4386329692 cites W2064110992 @default.
• W4386329692 cites W2064940016 @default.
• W4386329692 cites W2066091651 @default.
• W4386329692 cites W2066419206 @default.
• W4386329692 cites W2067589373 @default.
• W4386329692 cites W2067813837 @default.
• W4386329692 cites W2068015354 @default.
• W4386329692 cites W2069231491 @default.
• W4386329692 cites W2069426959 @default.
• W4386329692 cites W2069657851 @default.
• W4386329692 cites W2072427931 @default.
• W4386329692 cites W2077792190 @default.
• W4386329692 cites W2079491525 @default.
• W4386329692 cites W2081828196 @default.
• W4386329692 cites W2083022185 @default.
• W4386329692 cites W2083422615 @default.
• W4386329692 cites W2083926404 @default.
• W4386329692 cites W2085432081 @default.
• W4386329692 cites W2090282154 @default.
• W4386329692 cites W2090283458 @default.
• W4386329692 cites W2090399399 @default.

• next