FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386350363> ?p ?o ?g. }

• W4386350363 endingPage "331" @default.
• W4386350363 startingPage "325" @default.
• W4386350363 abstract "The article presents the results of histopathological and immunohistochemical studies of three types of equine skin neoplasms, classified as type 2 fibroblastic sarcoid based on their morphological features. The tumours were localized in the abdominal area, macroscopically presented as dense, fleshy formations without a stalk, yet with small ulcers on the surface. Infection of horses could have occurred through direct or indirect contact with other infected horses and cattle, as well as through insects. Histological examination of the sarcoid established that the epidermis was in a state of hyperkeratosis and acanthosis, with the formation of numerous projections that penetrated deeply into the dermis. The boundaries between the papillary and reticular layers of the dermis were not visualized; the defining feature was the chaotic spindle-shaped fibroblasts that formed a significant number of dense whirl-like structures, or moire patterns, which encircled vessels of a varying caliber. The cell nuclei were predominantly round-shaped and hyperchromatic. Present were both typical and atypical mitotic figures. Replacement of loose connective tissue with collagen fibers was observed intradermally. Upon studying the morphological structure of the sarcoid on semi-thin sections, significant vascularization was observed. Spindle-shaped fibrocytes with branched processes and elongated nuclei were located around vessels of varying sizes, exhibiting well-differentiated single or double nuclei. Fibroblasts of various shapes and sizes with round nuclei were randomly distributed throughout the entire area of the neoplasm. The bulk of the sarcoid consisted of collagen fibers, which turned pink when exposed to methylene blue and further exposure to acid fuchsin. Immunohistochemical studies revealed intense vimentin-positive expression in the sarcoid cells, confirming the hypothesis of their mesodermal origin. Upon detecting Ki-67 antibodies in the sarcoids from three clinical cases, a significant number of cells in the G1 and S phases of mitosis were discovered; the cell nuclei and karyoplasm were stained brown. These actively proliferating cells of the neoplasm constitute the growth fraction of the tumour and point to a high risk of recurrence and malignancy." @default.
• W4386350363 created "2023-09-02" @default.
• W4386350363 creator A5030215111 @default.
• W4386350363 creator A5041104283 @default.
• W4386350363 creator A5069153892 @default.
• W4386350363 date "2023-06-17" @default.
• W4386350363 modified "2023-10-16" @default.
• W4386350363 title "Histological and immunohistochemical changes in equine sarcoids" @default.
• W4386350363 cites W1895786380 @default.
• W4386350363 cites W1965038309 @default.
• W4386350363 cites W1971091021 @default.
• W4386350363 cites W1994250985 @default.
• W4386350363 cites W1996160840 @default.
• W4386350363 cites W1997082471 @default.
• W4386350363 cites W2001659704 @default.
• W4386350363 cites W2002418102 @default.
• W4386350363 cites W2004252342 @default.
• W4386350363 cites W2012230957 @default.
• W4386350363 cites W2013444566 @default.
• W4386350363 cites W2014000152 @default.
• W4386350363 cites W2019254190 @default.
• W4386350363 cites W2022324744 @default.
• W4386350363 cites W2025050750 @default.
• W4386350363 cites W2027970579 @default.
• W4386350363 cites W2033829874 @default.
• W4386350363 cites W2034269086 @default.
• W4386350363 cites W2040967677 @default.
• W4386350363 cites W2042542395 @default.
• W4386350363 cites W2054340000 @default.
• W4386350363 cites W2058379113 @default.
• W4386350363 cites W2059611309 @default.
• W4386350363 cites W2063907439 @default.
• W4386350363 cites W2064240992 @default.
• W4386350363 cites W2065892246 @default.
• W4386350363 cites W2068091512 @default.
• W4386350363 cites W2082556895 @default.
• W4386350363 cites W2124840015 @default.
• W4386350363 cites W2135349598 @default.
• W4386350363 cites W2138454538 @default.
• W4386350363 cites W2142778308 @default.
• W4386350363 cites W2151752998 @default.
• W4386350363 cites W2153922681 @default.
• W4386350363 cites W2171964896 @default.
• W4386350363 cites W2267418770 @default.
• W4386350363 cites W2283271823 @default.
• W4386350363 cites W2314203153 @default.
• W4386350363 cites W2328400633 @default.
• W4386350363 cites W2422636224 @default.
• W4386350363 cites W2533076174 @default.
• W4386350363 cites W2900902086 @default.
• W4386350363 cites W3041407477 @default.
• W4386350363 cites W3111413729 @default.
• W4386350363 cites W3196566728 @default.
• W4386350363 cites W4206262267 @default.
• W4386350363 cites W4245857018 @default.
• W4386350363 cites W4323287682 @default.
• W4386350363 cites W4362465758 @default.
• W4386350363 cites W4366597457 @default.
• W4386350363 doi "https://doi.org/10.15421/022348" @default.
• W4386350363 hasPublicationYear "2023" @default.
• W4386350363 type Work @default.
• W4386350363 citedByCount "0" @default.
• W4386350363 crossrefType "journal-article" @default.
• W4386350363 hasAuthorship W4386350363A5030215111 @default.
• W4386350363 hasAuthorship W4386350363A5041104283 @default.
• W4386350363 hasAuthorship W4386350363A5069153892 @default.
• W4386350363 hasBestOaLocation W43863503631 @default.
• W4386350363 hasConcept C105702510 @default.
• W4386350363 hasConcept C142724271 @default.
• W4386350363 hasConcept C204232928 @default.
• W4386350363 hasConcept C26064473 @default.
• W4386350363 hasConcept C2776458125 @default.
• W4386350363 hasConcept C2777624698 @default.
• W4386350363 hasConcept C2778478263 @default.
• W4386350363 hasConcept C2779915019 @default.
• W4386350363 hasConcept C2910760841 @default.
• W4386350363 hasConcept C3019965523 @default.
• W4386350363 hasConcept C518705261 @default.
• W4386350363 hasConcept C71924100 @default.
• W4386350363 hasConcept C86803240 @default.
• W4386350363 hasConcept C95190701 @default.
• W4386350363 hasConceptScore W4386350363C105702510 @default.
• W4386350363 hasConceptScore W4386350363C142724271 @default.
• W4386350363 hasConceptScore W4386350363C204232928 @default.
• W4386350363 hasConceptScore W4386350363C26064473 @default.
• W4386350363 hasConceptScore W4386350363C2776458125 @default.
• W4386350363 hasConceptScore W4386350363C2777624698 @default.
• W4386350363 hasConceptScore W4386350363C2778478263 @default.
• W4386350363 hasConceptScore W4386350363C2779915019 @default.
• W4386350363 hasConceptScore W4386350363C2910760841 @default.
• W4386350363 hasConceptScore W4386350363C3019965523 @default.
• W4386350363 hasConceptScore W4386350363C518705261 @default.
• W4386350363 hasConceptScore W4386350363C71924100 @default.
• W4386350363 hasConceptScore W4386350363C86803240 @default.
• W4386350363 hasConceptScore W4386350363C95190701 @default.
• W4386350363 hasIssue "2" @default.
• W4386350363 hasLocation W43863503631 @default.
• W4386350363 hasOpenAccess W4386350363 @default.

• next