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• W4386352012 abstract "Triazole, sulfonamide and sulfonyl urea derivatives of N-acylhomoserine lactones (AHLs) have been prepared from homoserine lactone hydrobromide which in turn is derived from L-methionine. The molecules were screened against Chromobacterium violaceum ATCC 12472 for their quorum sensing inhibitory (QSI) activity. Among them, compounds 6, 7 and 14 were exhibited comparable antibacterial activities with reference to penicillin and streptomycin as 37.5 µg/mL, while compounds 7, 13 and 17 exhibited promising QSI activity. These compounds represent a synthetically accessible class of AHL analogs could find utility to improve their potency." @default.
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• W4386352012 date "2024-01-01" @default.
• W4386352012 modified "2023-10-07" @default.
• W4386352012 title "Design, synthesis and biological evaluation of triazole, sulfonamide and sulfonyl urea derivatives of N-acylhomoserine lactone as quorum sensing inhibitors" @default.
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• W4386352012 doi "https://doi.org/10.1016/j.molstruc.2023.136547" @default.
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