FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386366105> ?p ?o ?g. }

• W4386366105 endingPage "e001525" @default.
• W4386366105 startingPage "e001525" @default.
• W4386366105 abstract "Acute respiratory distress syndrome (ARDS) is the most severe form of lung injury, rendering gaseous exchange insufficient, leading to respiratory failure. Despite over 50 years of research on the treatment of ARDS when developed from illnesses such as sepsis and pneumonia, mortality remains high, and no robust pharmacological treatments exist. The progression of SARS-CoV-2 infections to ARDS during the recent global pandemic led to a surge in the number of clinical trials on the condition. Understandably, this explosion in new research focused on COVID-19 ARDS (CARDS) rather than ARDS when developed from other illnesses, yet differences in pathology between the two conditions mean that optimal treatment for them may be distinct.The aim of the present work is to assess whether new therapeutic interventions that have been developed for the treatment of CARDS may also hold strong potential in the treatment of ARDS when developed from other illnesses. The study objectives are achieved through a systematic review of clinical trials.The COVID-19 pandemic led to the identification of various therapeutic interventions for CARDS, some but not all of which are optimal for the management of ARDS. Interventions more suited to CARDS pathology include antithrombotics and biologic agents, such as cytokine inhibitors. Cell-based therapies, on the other hand, show promise in the treatment of both conditions, attributed to their broad mechanisms of action and the overlap in the clinical manifestations of the conditions. A shift towards personalised treatments for both CARDS and ARDS, as reflected through the increasing use of biologics, is also evident.As ongoing CARDS clinical trials progress, their findings are likely to have important implications that alter the management of ARDS in patients that develop the condition from illnesses other than COVID-19 in the future." @default.
• W4386366105 created "2023-09-02" @default.
• W4386366105 creator A5002914756 @default.
• W4386366105 creator A5021918263 @default.
• W4386366105 creator A5092728873 @default.
• W4386366105 date "2023-09-01" @default.
• W4386366105 modified "2023-09-27" @default.
• W4386366105 title "Acute respiratory distress syndrome: potential of therapeutic interventions effective in treating progression from COVID-19 to treat progression from other illnesses—a systematic review" @default.
• W4386366105 cites W105869727 @default.
• W4386366105 cites W1597689181 @default.
• W4386366105 cites W1887774545 @default.
• W4386366105 cites W1967936089 @default.
• W4386366105 cites W1995070580 @default.
• W4386366105 cites W1998457189 @default.
• W4386366105 cites W2001899439 @default.
• W4386366105 cites W2021543873 @default.
• W4386366105 cites W2050475327 @default.
• W4386366105 cites W2057453699 @default.
• W4386366105 cites W2097036700 @default.
• W4386366105 cites W2102501066 @default.
• W4386366105 cites W2114404607 @default.
• W4386366105 cites W2115186092 @default.
• W4386366105 cites W2125766343 @default.
• W4386366105 cites W2131135326 @default.
• W4386366105 cites W2131228216 @default.
• W4386366105 cites W2147291922 @default.
• W4386366105 cites W2166849256 @default.
• W4386366105 cites W2169421618 @default.
• W4386366105 cites W2170984368 @default.
• W4386366105 cites W2263008453 @default.
• W4386366105 cites W2333943198 @default.
• W4386366105 cites W2515878778 @default.
• W4386366105 cites W2607594773 @default.
• W4386366105 cites W2609466732 @default.
• W4386366105 cites W2620241325 @default.
• W4386366105 cites W2753321278 @default.
• W4386366105 cites W2901220228 @default.
• W4386366105 cites W2962814950 @default.
• W4386366105 cites W2969266738 @default.
• W4386366105 cites W3000724448 @default.
• W4386366105 cites W3029098890 @default.
• W4386366105 cites W3032503858 @default.
• W4386366105 cites W3036026378 @default.
• W4386366105 cites W3036101703 @default.
• W4386366105 cites W3043249174 @default.
• W4386366105 cites W3043294914 @default.
• W4386366105 cites W3092135625 @default.
• W4386366105 cites W3095596498 @default.
• W4386366105 cites W3100691159 @default.
• W4386366105 cites W3107195649 @default.
• W4386366105 cites W3126400175 @default.
• W4386366105 cites W3135838854 @default.
• W4386366105 cites W3143194253 @default.
• W4386366105 cites W3151985943 @default.
• W4386366105 cites W3164862816 @default.
• W4386366105 cites W3167553362 @default.
• W4386366105 cites W3195579001 @default.
• W4386366105 cites W3196496924 @default.
• W4386366105 cites W3200849039 @default.
• W4386366105 cites W3200993794 @default.
• W4386366105 cites W3203445105 @default.
• W4386366105 cites W3213886386 @default.
• W4386366105 cites W4200247674 @default.
• W4386366105 cites W4200530390 @default.
• W4386366105 cites W4205879827 @default.
• W4386366105 cites W4210350434 @default.
• W4386366105 cites W4211250103 @default.
• W4386366105 cites W4237939525 @default.
• W4386366105 cites W4280644200 @default.
• W4386366105 cites W4281988270 @default.
• W4386366105 cites W4285751103 @default.
• W4386366105 cites W4292168348 @default.
• W4386366105 cites W4307996340 @default.
• W4386366105 cites W4372286281 @default.
• W4386366105 cites W4382051195 @default.
• W4386366105 doi "https://doi.org/10.1136/bmjresp-2022-001525" @default.
• W4386366105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37657844" @default.
• W4386366105 hasPublicationYear "2023" @default.
• W4386366105 type Work @default.
• W4386366105 citedByCount "0" @default.
• W4386366105 crossrefType "journal-article" @default.
• W4386366105 hasAuthorship W4386366105A5002914756 @default.
• W4386366105 hasAuthorship W4386366105A5021918263 @default.
• W4386366105 hasAuthorship W4386366105A5092728873 @default.
• W4386366105 hasBestOaLocation W43863661051 @default.
• W4386366105 hasConcept C118552586 @default.
• W4386366105 hasConcept C126322002 @default.
• W4386366105 hasConcept C142724271 @default.
• W4386366105 hasConcept C177713679 @default.
• W4386366105 hasConcept C27415008 @default.
• W4386366105 hasConcept C2776348555 @default.
• W4386366105 hasConcept C2777714996 @default.
• W4386366105 hasConcept C2777914695 @default.
• W4386366105 hasConcept C2779134260 @default.
• W4386366105 hasConcept C3008058167 @default.
• W4386366105 hasConcept C524204448 @default.
• W4386366105 hasConcept C535046627 @default.
• W4386366105 hasConcept C71924100 @default.

• next