Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386370424> ?p ?o ?g. }
- W4386370424 endingPage "1867" @default.
- W4386370424 startingPage "1867" @default.
- W4386370424 abstract "The endosomal sorting complex required for transport (ESCRT) machinery is essential for the budding of retroviruses such as human immunodeficiency virus (HIV) and bovine foamy virus (BFV), which rely on their late domain to recruit ESCRT complexes to facilitate budding. However, the impact of intracellular host proteins on BFV budding remains poorly understood. In this study, we aimed to investigate the impact of CCL2 on BFV budding and interactions with key host proteins. Our results indicate that CCL2 promotes BFV budding in an ALG-2-interacting protein X (Alix)-dependent manner by enhancing the interaction between Alix and BFV Gag (BGag). Notably, we found a link between Alix, BGag and CCL2, with Alix mediating the interaction between the latter two. Furthermore, we observed that natural host bovine CCL2 also has a facilitating role in the budding process of BFV, similar to human CCL2. Taken together, these results demonstrate that CCL2 promotes BFV budding by enhancing the Alix-BGag association." @default.
- W4386370424 created "2023-09-02" @default.
- W4386370424 creator A5023867715 @default.
- W4386370424 creator A5039205452 @default.
- W4386370424 creator A5044181742 @default.
- W4386370424 creator A5081675173 @default.
- W4386370424 creator A5088471540 @default.
- W4386370424 date "2023-09-01" @default.
- W4386370424 modified "2023-10-08" @default.
- W4386370424 title "Effects of Chemokine Ligand 2 on Budding of Bovine Foamy Virus" @default.
- W4386370424 cites W1514600503 @default.
- W4386370424 cites W1592162857 @default.
- W4386370424 cites W166593606 @default.
- W4386370424 cites W1972916439 @default.
- W4386370424 cites W1982606786 @default.
- W4386370424 cites W1984285433 @default.
- W4386370424 cites W1993161188 @default.
- W4386370424 cites W2025859329 @default.
- W4386370424 cites W2028972269 @default.
- W4386370424 cites W2032023518 @default.
- W4386370424 cites W2035222818 @default.
- W4386370424 cites W2035954317 @default.
- W4386370424 cites W2045388509 @default.
- W4386370424 cites W2053587767 @default.
- W4386370424 cites W2074130602 @default.
- W4386370424 cites W2082115176 @default.
- W4386370424 cites W2096549714 @default.
- W4386370424 cites W2097916669 @default.
- W4386370424 cites W2106872247 @default.
- W4386370424 cites W2108894254 @default.
- W4386370424 cites W2115052708 @default.
- W4386370424 cites W2116740051 @default.
- W4386370424 cites W2116929075 @default.
- W4386370424 cites W2120463956 @default.
- W4386370424 cites W2124504184 @default.
- W4386370424 cites W2130314959 @default.
- W4386370424 cites W2130448025 @default.
- W4386370424 cites W2136330246 @default.
- W4386370424 cites W2140094437 @default.
- W4386370424 cites W2154810129 @default.
- W4386370424 cites W2157309681 @default.
- W4386370424 cites W2161547077 @default.
- W4386370424 cites W233645389 @default.
- W4386370424 cites W2559077904 @default.
- W4386370424 cites W2747891174 @default.
- W4386370424 cites W2756255487 @default.
- W4386370424 cites W2760141941 @default.
- W4386370424 cites W2943912459 @default.
- W4386370424 cites W2948571638 @default.
- W4386370424 cites W2955679321 @default.
- W4386370424 cites W2990354174 @default.
- W4386370424 cites W3082355598 @default.
- W4386370424 cites W3113225533 @default.
- W4386370424 cites W3117560261 @default.
- W4386370424 cites W3133263773 @default.
- W4386370424 cites W3163840476 @default.
- W4386370424 cites W4214907194 @default.
- W4386370424 cites W4224268409 @default.
- W4386370424 doi "https://doi.org/10.3390/v15091867" @default.
- W4386370424 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37766274" @default.
- W4386370424 hasPublicationYear "2023" @default.
- W4386370424 type Work @default.
- W4386370424 citedByCount "0" @default.
- W4386370424 crossrefType "journal-article" @default.
- W4386370424 hasAuthorship W4386370424A5023867715 @default.
- W4386370424 hasAuthorship W4386370424A5039205452 @default.
- W4386370424 hasAuthorship W4386370424A5044181742 @default.
- W4386370424 hasAuthorship W4386370424A5081675173 @default.
- W4386370424 hasAuthorship W4386370424A5088471540 @default.
- W4386370424 hasBestOaLocation W43863704241 @default.
- W4386370424 hasConcept C102747710 @default.
- W4386370424 hasConcept C104317684 @default.
- W4386370424 hasConcept C13373296 @default.
- W4386370424 hasConcept C143876685 @default.
- W4386370424 hasConcept C145059251 @default.
- W4386370424 hasConcept C159047783 @default.
- W4386370424 hasConcept C185592680 @default.
- W4386370424 hasConcept C198410946 @default.
- W4386370424 hasConcept C203014093 @default.
- W4386370424 hasConcept C20518536 @default.
- W4386370424 hasConcept C2522874641 @default.
- W4386370424 hasConcept C2776914184 @default.
- W4386370424 hasConcept C2778283623 @default.
- W4386370424 hasConcept C54355233 @default.
- W4386370424 hasConcept C79879829 @default.
- W4386370424 hasConcept C86803240 @default.
- W4386370424 hasConcept C95444343 @default.
- W4386370424 hasConceptScore W4386370424C102747710 @default.
- W4386370424 hasConceptScore W4386370424C104317684 @default.
- W4386370424 hasConceptScore W4386370424C13373296 @default.
- W4386370424 hasConceptScore W4386370424C143876685 @default.
- W4386370424 hasConceptScore W4386370424C145059251 @default.
- W4386370424 hasConceptScore W4386370424C159047783 @default.
- W4386370424 hasConceptScore W4386370424C185592680 @default.
- W4386370424 hasConceptScore W4386370424C198410946 @default.
- W4386370424 hasConceptScore W4386370424C203014093 @default.
- W4386370424 hasConceptScore W4386370424C20518536 @default.
- W4386370424 hasConceptScore W4386370424C2522874641 @default.