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- W4386398850 endingPage "132449" @default.
- W4386398850 startingPage "132449" @default.
- W4386398850 abstract "Polyethylene (PE) is a widely used plastic known for its resistance to biodegradation, posing a significant environmental challenge. Recent advances have shed light on microorganisms and insects capable of breaking down PE and identified potential PE-degrading enzymes (PEases), hinting at the possibility of PE biorecycling. Research on enzymatic PE degradation is still in its early stages, especially compared to the progress made with polyethylene terephthalate (PET). While PET hydrolases have been extensively studied and engineered for improved performance, even the products of PEases remain mostly undefined. This Perspective analyzes the current state of enzymatic PE degradation research, highlighting obstacles in the search for bona fide PEases and suggesting areas for future exploration. A critical challenge impeding progress in this field stems from the inert nature of the C-C and C-H bonds of PE. Furthermore, breaking down PE into small molecules using only one monofunctional enzyme is theoretically impossible. Overcoming these obstacles requires identifying enzymatic pathways, which can be facilitated using emerging technologies like omics, structure-based design, and computer-assisted engineering of enzymes. Understanding the mechanisms underlying PE enzymatic biodegradation is crucial for research progress and for identifying potential solutions to the global plastic pollution crisis." @default.
- W4386398850 created "2023-09-04" @default.
- W4386398850 creator A5008535258 @default.
- W4386398850 creator A5018369793 @default.
- W4386398850 creator A5041659230 @default.
- W4386398850 creator A5050847765 @default.
- W4386398850 date "2023-10-01" @default.
- W4386398850 modified "2023-09-27" @default.
- W4386398850 title "Enzymatic Polyethylene Biorecycling: Confronting Challenges and Shaping the Future" @default.
- W4386398850 cites W1582890276 @default.
- W4386398850 cites W1602071118 @default.
- W4386398850 cites W1794778178 @default.
- W4386398850 cites W1803102843 @default.
- W4386398850 cites W1902837844 @default.
- W4386398850 cites W1966666273 @default.
- W4386398850 cites W1996316553 @default.
- W4386398850 cites W1998266307 @default.
- W4386398850 cites W2014497823 @default.
- W4386398850 cites W2031529581 @default.
- W4386398850 cites W2049925893 @default.
- W4386398850 cites W2053705771 @default.
- W4386398850 cites W2063083328 @default.
- W4386398850 cites W2063866602 @default.
- W4386398850 cites W2075174907 @default.
- W4386398850 cites W2079444234 @default.
- W4386398850 cites W2082445708 @default.
- W4386398850 cites W2086882881 @default.
- W4386398850 cites W2093094369 @default.
- W4386398850 cites W2097772169 @default.
- W4386398850 cites W2111804569 @default.
- W4386398850 cites W2124218014 @default.
- W4386398850 cites W2127870464 @default.
- W4386398850 cites W2130479394 @default.
- W4386398850 cites W2138934239 @default.
- W4386398850 cites W2141962696 @default.
- W4386398850 cites W2147511428 @default.
- W4386398850 cites W2156782854 @default.
- W4386398850 cites W2182009706 @default.
- W4386398850 cites W2294707565 @default.
- W4386398850 cites W2326807703 @default.
- W4386398850 cites W2400947447 @default.
- W4386398850 cites W2467507488 @default.
- W4386398850 cites W2471004897 @default.
- W4386398850 cites W2491839573 @default.
- W4386398850 cites W2559840391 @default.
- W4386398850 cites W2570707817 @default.
- W4386398850 cites W2598313020 @default.
- W4386398850 cites W2600922952 @default.
- W4386398850 cites W2607832308 @default.
- W4386398850 cites W2625250769 @default.
- W4386398850 cites W2737217596 @default.
- W4386398850 cites W2743007812 @default.
- W4386398850 cites W2765798370 @default.
- W4386398850 cites W2790371876 @default.
- W4386398850 cites W2803195089 @default.
- W4386398850 cites W2804247570 @default.
- W4386398850 cites W2901716023 @default.
- W4386398850 cites W2902013344 @default.
- W4386398850 cites W2916304511 @default.
- W4386398850 cites W2922444498 @default.
- W4386398850 cites W2922676833 @default.
- W4386398850 cites W2944245644 @default.
- W4386398850 cites W2966892017 @default.
- W4386398850 cites W2985579226 @default.
- W4386398850 cites W2993586016 @default.
- W4386398850 cites W2996363503 @default.
- W4386398850 cites W3005332201 @default.
- W4386398850 cites W3007644676 @default.
- W4386398850 cites W3015207233 @default.
- W4386398850 cites W3019750061 @default.
- W4386398850 cites W3029021866 @default.
- W4386398850 cites W3030925007 @default.
- W4386398850 cites W3032220059 @default.
- W4386398850 cites W3089916935 @default.
- W4386398850 cites W3094813377 @default.
- W4386398850 cites W3113296337 @default.
- W4386398850 cites W3119518863 @default.
- W4386398850 cites W3120627598 @default.
- W4386398850 cites W3121331573 @default.
- W4386398850 cites W3127691497 @default.
- W4386398850 cites W3154072846 @default.
- W4386398850 cites W3159449097 @default.
- W4386398850 cites W3167486698 @default.
- W4386398850 cites W3175616153 @default.
- W4386398850 cites W3177828909 @default.
- W4386398850 cites W3181026315 @default.
- W4386398850 cites W3182809237 @default.
- W4386398850 cites W3183835656 @default.
- W4386398850 cites W3184481905 @default.
- W4386398850 cites W320528287 @default.
- W4386398850 cites W3209595716 @default.
- W4386398850 cites W3216341763 @default.
- W4386398850 cites W4200074358 @default.
- W4386398850 cites W4207082438 @default.
- W4386398850 cites W4213047134 @default.
- W4386398850 cites W4220938498 @default.
- W4386398850 cites W4220976344 @default.
- W4386398850 cites W4224988655 @default.