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- W4386399440 abstract "Sogatella furcifera (Horváth), which mainly threatens rice, shows various levels of pesticide resistance due to long-term overuse of pesticides. Our resistance monitoring of 20 field populations in Sichuan, China, revealed that they were susceptible to highly resistant toward pymetrozine (0.4-142.2 RR), and JL21 reached the highest level of resistance. The JL21 population exhibited cross-resistance to triflumezopyrim and dinotefuran but sensitivity to sulfoxaflor, acetamiprid, clothianidin, and nitenpyram. The increased P450 activity were support to involve in pymetrozine resistance by detoxification enzyme activities and synergist determination. Among 16 candidate P450 genes, CYP6FJ3 (5.25-fold) was the most up-regulated in JL21, while no significant change was found after LC25 pymetrozine treatment. Furthermore, the knockdown by RNAi and heterologous overexpression by the GAL4/UAS system confirmed that the CYP6FJ3 overexpression was involved in the pymetrozine resistance, and recombination in vitro confirmed that CYP6FJ3 could hydroxylate pymetrozine. Therefore, the overexpression of CYP6FJ3 promotes pymetrozine metabolic resistance in S. furcifera." @default.
- W4386399440 created "2023-09-04" @default.
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- W4386399440 date "2023-09-03" @default.
- W4386399440 modified "2023-10-18" @default.
- W4386399440 title "Metabolic Resistance of <i>Sogatella furcifera</i> (Hemiptera: Delphacidae) toward Pymetrozine Involves the Overexpression of <i>CYP6FJ3</i>" @default.
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- W4386399440 doi "https://doi.org/10.1021/acs.jafc.3c03617" @default.
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