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• W4386415281 abstract "Abstract Background Dissolved oxygen has known paramagnetic effects in magnetic resonance imaging (MRI). The aim of this study was to compare the effects of normobaric oxygenation (NBO) and hyperbaric oxygenation (HBO) on human brain MRI signal intensities. Patients and methods Baseline brain MRI was performed in 17 healthy subjects (mean age 27.8 ± 3.2). MRI was repeated after exposure to the NBO and HBO at different time points (0 min, 25 min, 50 min). Signal intensities in T 1 -weighted, T 2 -weighted images and fluid attenuated inversion recovery (FLAIR) signal intensities of several intracranial structures were compared between NBO and HBO. Results Increased T 1 -weighted signal intensities were observed in white and deep grey brain matter, cerebrospinal fluid (CSF), venous blood and vitreous body after exposure to NBO as well as to HBO compared to baseline (Dunnett's test, p < 0.05) without significant differences between both protocols. There was also no significant difference in T 2 -weighted signal intensities between NBO and HBO. FLAIR signal intensities were increased only in the vitreous body after NBO and HBO and FLAIR signal of caudate nucleus was decreased after NBO (Dunnett's test, p < 0.05). The statistically significant differences in FLAIR signal intensities were found between NBO and HBO (paired t-test, p < 0.05) in most observed brain structures (paired t-test, p < 0.05). Conclusions Our results show that NBO and HBO alters signal intensities T 1 -weighted and FLAIR images of human brain. The differences between NBO and HBO are most pronounced in FLAIR imaging." @default.
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• W4386415281 date "2023-09-01" @default.
• W4386415281 modified "2023-10-18" @default.
• W4386415281 title "The effects of normobaric and hyperbaric oxygenation on MRI signal intensities in <i>T₁ </i>-weighted, <i>T₂ </i>-weighted and FLAIR images in human brain" @default.
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• W4386415281 doi "https://doi.org/10.2478/raon-2023-0043" @default.
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