Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386418040> ?p ?o ?g. }
- W4386418040 endingPage "1858" @default.
- W4386418040 startingPage "1858" @default.
- W4386418040 abstract "Neural stem cells (NSCs) have previously been described up to the adult stage in the rat cochlear nucleus (CN). A decreasing neurogenic potential was observed with critical changes around hearing onset. A better understanding of molecular factors affecting NSCs and neurogenesis is of interest as they represent potential targets to treat the cause of neurologically based hearing disorders. The role of genes affecting NSC development and neurogenesis in CN over time on hearing capacity has remained unclear. This study investigated the mRNA abundance of genes influencing NSCs and neurogenesis in rats’ CN over time. The CN of rats on postnatal days 6, 12, and 24 were examined. Real-time quantitative polymerase chain reaction arrays were used to compare mRNA levels of 84 genes relevant to NSCs and neurogenesis. Age- and hearing-specific patterns of changes in mRNA abundance of neurogenically relevant genes were detected in the rat CN. Additionally, crucial neurogenic factors with significant and relevant influence on neurogenesis were identified. The results of this work should contribute to a better understanding of the molecular mechanisms underlying the neurogenesis of the auditory pathway." @default.
- W4386418040 created "2023-09-05" @default.
- W4386418040 creator A5006070087 @default.
- W4386418040 creator A5029230429 @default.
- W4386418040 creator A5032531503 @default.
- W4386418040 creator A5040036253 @default.
- W4386418040 creator A5042270846 @default.
- W4386418040 creator A5065544465 @default.
- W4386418040 creator A5070837440 @default.
- W4386418040 creator A5082906602 @default.
- W4386418040 date "2023-09-02" @default.
- W4386418040 modified "2023-10-17" @default.
- W4386418040 title "mRNA Abundance of Neurogenic Factors Correlates with Hearing Capacity in Auditory Brainstem Nuclei of the Rat" @default.
- W4386418040 cites W1487695731 @default.
- W4386418040 cites W1501115822 @default.
- W4386418040 cites W1575310353 @default.
- W4386418040 cites W1577577364 @default.
- W4386418040 cites W1832678746 @default.
- W4386418040 cites W1927606887 @default.
- W4386418040 cites W1963686368 @default.
- W4386418040 cites W1963900159 @default.
- W4386418040 cites W1964700442 @default.
- W4386418040 cites W1965036826 @default.
- W4386418040 cites W1968911616 @default.
- W4386418040 cites W1968983678 @default.
- W4386418040 cites W1972628959 @default.
- W4386418040 cites W1974097563 @default.
- W4386418040 cites W1974373320 @default.
- W4386418040 cites W1974379562 @default.
- W4386418040 cites W1976148134 @default.
- W4386418040 cites W1976967262 @default.
- W4386418040 cites W1979867194 @default.
- W4386418040 cites W1982327152 @default.
- W4386418040 cites W1982357598 @default.
- W4386418040 cites W1982637815 @default.
- W4386418040 cites W1982662535 @default.
- W4386418040 cites W1982942777 @default.
- W4386418040 cites W1982944995 @default.
- W4386418040 cites W1985912987 @default.
- W4386418040 cites W1985947763 @default.
- W4386418040 cites W1986346910 @default.
- W4386418040 cites W1988401988 @default.
- W4386418040 cites W1991338371 @default.
- W4386418040 cites W1991811507 @default.
- W4386418040 cites W1992803636 @default.
- W4386418040 cites W1996531547 @default.
- W4386418040 cites W1999321510 @default.
- W4386418040 cites W1999511738 @default.
- W4386418040 cites W2003863108 @default.
- W4386418040 cites W2004293316 @default.
- W4386418040 cites W2005797914 @default.
- W4386418040 cites W2006225302 @default.
- W4386418040 cites W2010906942 @default.
- W4386418040 cites W2011978143 @default.
- W4386418040 cites W2012246166 @default.
- W4386418040 cites W2014404364 @default.
- W4386418040 cites W2014407542 @default.
- W4386418040 cites W2015766782 @default.
- W4386418040 cites W2015914145 @default.
- W4386418040 cites W2017438223 @default.
- W4386418040 cites W2019667326 @default.
- W4386418040 cites W2021766835 @default.
- W4386418040 cites W2023799799 @default.
- W4386418040 cites W2025201512 @default.
- W4386418040 cites W2030251237 @default.
- W4386418040 cites W2030696262 @default.
- W4386418040 cites W2032539106 @default.
- W4386418040 cites W2038772759 @default.
- W4386418040 cites W2043655216 @default.
- W4386418040 cites W2044015089 @default.
- W4386418040 cites W2051020842 @default.
- W4386418040 cites W2052759132 @default.
- W4386418040 cites W2052962218 @default.
- W4386418040 cites W2056780622 @default.
- W4386418040 cites W2057164201 @default.
- W4386418040 cites W2060728994 @default.
- W4386418040 cites W2060854925 @default.
- W4386418040 cites W2064361803 @default.
- W4386418040 cites W2065318766 @default.
- W4386418040 cites W2068443851 @default.
- W4386418040 cites W2073003305 @default.
- W4386418040 cites W2074121563 @default.
- W4386418040 cites W2074860914 @default.
- W4386418040 cites W2075974101 @default.
- W4386418040 cites W2076736456 @default.
- W4386418040 cites W2077791460 @default.
- W4386418040 cites W2081050947 @default.
- W4386418040 cites W2084652820 @default.
- W4386418040 cites W2085059773 @default.
- W4386418040 cites W2086092967 @default.
- W4386418040 cites W2088355263 @default.
- W4386418040 cites W2088969512 @default.
- W4386418040 cites W2089252994 @default.
- W4386418040 cites W2089394861 @default.
- W4386418040 cites W2089589904 @default.
- W4386418040 cites W2089625282 @default.
- W4386418040 cites W2091496842 @default.
- W4386418040 cites W2093049632 @default.