Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386423219> ?p ?o ?g. }
- W4386423219 endingPage "655" @default.
- W4386423219 startingPage "630" @default.
- W4386423219 abstract "Sodium-glucose cotransporter-2 (SGLT-2) inhibitors were once known as a class of glycemic-lowering agents to treat type 2 diabetes. As the evolving evidence from recent cardiorenal trials on these agents has shown—e.g., EMPA-REG OUTCOME, DECLARE-TIMI 58, CANVAS Program, DAPA-CKD—disclosing their benefits beyond glycemic management, SGLT-2 inhibitors have stimulated a shift in the management of T2DM and its comorbidities, specifically preventing cardiovascular events in people with ASCVD, preventing heart failure hospitalizations, and delaying the progression of chronic kidney disease. As a result, their usage beyond glycemic management has been included in clinical practice guidelines. Although SGLT-2 inhibitors have shown promising results in cardiorenal outcomes, patients have not had equal access to these agents, at least in the United States, suggesting a systemic issue of health inequity. This review article explores the mechanisms by which cardiorenal benefits are offered, the results of the landmark clinical trials for these agents, and their place in therapy." @default.
- W4386423219 created "2023-09-05" @default.
- W4386423219 creator A5038271262 @default.
- W4386423219 creator A5040175704 @default.
- W4386423219 creator A5048404332 @default.
- W4386423219 creator A5072950825 @default.
- W4386423219 date "2023-09-04" @default.
- W4386423219 modified "2023-09-30" @default.
- W4386423219 title "Exploring SGLT-2 Inhibitors: Benefits beyond the Glucose-Lowering Effect—What Is New in 2023?" @default.
- W4386423219 cites W1974864689 @default.
- W4386423219 cites W2065586075 @default.
- W4386423219 cites W2066620859 @default.
- W4386423219 cites W2072535229 @default.
- W4386423219 cites W2073935789 @default.
- W4386423219 cites W2128219379 @default.
- W4386423219 cites W2134304394 @default.
- W4386423219 cites W2135378280 @default.
- W4386423219 cites W2142065502 @default.
- W4386423219 cites W2146264128 @default.
- W4386423219 cites W2150959326 @default.
- W4386423219 cites W2343975335 @default.
- W4386423219 cites W2424539745 @default.
- W4386423219 cites W2553261268 @default.
- W4386423219 cites W2606994751 @default.
- W4386423219 cites W2626446274 @default.
- W4386423219 cites W2746903407 @default.
- W4386423219 cites W2750878728 @default.
- W4386423219 cites W2755863750 @default.
- W4386423219 cites W2765097799 @default.
- W4386423219 cites W2808915250 @default.
- W4386423219 cites W2883419804 @default.
- W4386423219 cites W2884466498 @default.
- W4386423219 cites W2900413769 @default.
- W4386423219 cites W2938583963 @default.
- W4386423219 cites W2939222610 @default.
- W4386423219 cites W2955084980 @default.
- W4386423219 cites W2974260792 @default.
- W4386423219 cites W2984886143 @default.
- W4386423219 cites W3007092184 @default.
- W4386423219 cites W3010708209 @default.
- W4386423219 cites W3042876448 @default.
- W4386423219 cites W3081830235 @default.
- W4386423219 cites W3088173406 @default.
- W4386423219 cites W3089283105 @default.
- W4386423219 cites W3092379111 @default.
- W4386423219 cites W3093773039 @default.
- W4386423219 cites W3100542962 @default.
- W4386423219 cites W3125563499 @default.
- W4386423219 cites W3153561131 @default.
- W4386423219 cites W3154796681 @default.
- W4386423219 cites W3211752197 @default.
- W4386423219 cites W4210395494 @default.
- W4386423219 cites W4210813649 @default.
- W4386423219 cites W4214512384 @default.
- W4386423219 cites W4220884848 @default.
- W4386423219 cites W4293353625 @default.
- W4386423219 cites W4293354639 @default.
- W4386423219 cites W4294771462 @default.
- W4386423219 cites W4306783667 @default.
- W4386423219 cites W4308183941 @default.
- W4386423219 cites W4322490198 @default.
- W4386423219 doi "https://doi.org/10.3390/endocrines4030045" @default.
- W4386423219 hasPublicationYear "2023" @default.
- W4386423219 type Work @default.
- W4386423219 citedByCount "0" @default.
- W4386423219 crossrefType "journal-article" @default.
- W4386423219 hasAuthorship W4386423219A5038271262 @default.
- W4386423219 hasAuthorship W4386423219A5040175704 @default.
- W4386423219 hasAuthorship W4386423219A5048404332 @default.
- W4386423219 hasAuthorship W4386423219A5072950825 @default.
- W4386423219 hasBestOaLocation W43864232191 @default.
- W4386423219 hasConcept C126322002 @default.
- W4386423219 hasConcept C134018914 @default.
- W4386423219 hasConcept C177713679 @default.
- W4386423219 hasConcept C2775887513 @default.
- W4386423219 hasConcept C2777180221 @default.
- W4386423219 hasConcept C2778198053 @default.
- W4386423219 hasConcept C2778653478 @default.
- W4386423219 hasConcept C2780473172 @default.
- W4386423219 hasConcept C2781309322 @default.
- W4386423219 hasConcept C535046627 @default.
- W4386423219 hasConcept C555293320 @default.
- W4386423219 hasConcept C71924100 @default.
- W4386423219 hasConceptScore W4386423219C126322002 @default.
- W4386423219 hasConceptScore W4386423219C134018914 @default.
- W4386423219 hasConceptScore W4386423219C177713679 @default.
- W4386423219 hasConceptScore W4386423219C2775887513 @default.
- W4386423219 hasConceptScore W4386423219C2777180221 @default.
- W4386423219 hasConceptScore W4386423219C2778198053 @default.
- W4386423219 hasConceptScore W4386423219C2778653478 @default.
- W4386423219 hasConceptScore W4386423219C2780473172 @default.
- W4386423219 hasConceptScore W4386423219C2781309322 @default.
- W4386423219 hasConceptScore W4386423219C535046627 @default.
- W4386423219 hasConceptScore W4386423219C555293320 @default.
- W4386423219 hasConceptScore W4386423219C71924100 @default.
- W4386423219 hasIssue "3" @default.
- W4386423219 hasLocation W43864232191 @default.
- W4386423219 hasOpenAccess W4386423219 @default.