FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386423929> ?p ?o ?g. }

• W4386423929 abstract "Abstract Introduction Genomic testing is a relatively new, disruptive and complex health technology with multiple clinical applications in rare diseases, cancer and infection control. Genomic testing is increasingly being implemented into clinical practice, following regulatory approval, funding and adoption in models of care, particularly in the area of rare disease diagnosis. A significant barrier to the adoption and implementation of genomic testing is funding. What remains unclear is what the cost of genomic testing is, what the underlying drivers of cost are and whether policy differences contribute to cost variance in different jurisdictions, such as the requirement to have staff with a medical license involved in testing. This costing study will be useful in future economic evaluations and health technology assessments to inform optimal levels of reimbursement and to support comprehensive and comparable assessment of healthcare resource utilisation in the delivery of genomic testing globally. Methods A framework is presented that focuses on uncovering the process of genomic testing for any given laboratory, evaluating its utilization and unit costs, and modelling the cost drivers and overall expenses associated with delivering genomic testing. The goal is to aid in refining and implementing policies regarding both the regulation and funding of genomic testing. A process-focused (activity-based) methodology is outlined, which encompasses resources, assesses individual cost components through a combination of bottom-up and top-down microcosting techniques and allows disaggregation of resource type and process step. Ethics and dissemination The outputs of the study will be reported a relevant regional genetics and health economics conferences, as well as submitted to a peer-reviewed journal focusing on genomics. Article Summary This method uses key stakeholder interviews, health care resource utilisation and unit cost data collection for estimating the economic cost of diagnostic genomic testing in Australia. Advancements may include time in motion studies or greater reporting detail but with a trade-off in feasibility. Probabilistic modelling addresses uncertainty inherent in input estimates. The study does not incorporate variations in testing pathways, such as resequencing stored DNA costs or reanalysis of existing sequencing data. Automating ongoing monitoring of changes in genomic testing workflows, resource utilisation and costs would be beneficial." @default.
• W4386423929 created "2023-09-05" @default.
• W4386423929 creator A5023451391 @default.
• W4386423929 creator A5065109936 @default.
• W4386423929 creator A5065973289 @default.
• W4386423929 creator A5078953009 @default.
• W4386423929 creator A5070165545 @default.
• W4386423929 date "2023-09-04" @default.
• W4386423929 modified "2023-10-15" @default.
• W4386423929 title "Development of a microcosting protocol to determine the economic cost of diagnostic genomic testing for rare diseases in Australia" @default.
• W4386423929 cites W1980883128 @default.
• W4386423929 cites W1998210425 @default.
• W4386423929 cites W2023723044 @default.
• W4386423929 cites W2032984286 @default.
• W4386423929 cites W2087951656 @default.
• W4386423929 cites W2325983326 @default.
• W4386423929 cites W2480575156 @default.
• W4386423929 cites W2582179052 @default.
• W4386423929 cites W2611580352 @default.
• W4386423929 cites W2793117922 @default.
• W4386423929 cites W2799691429 @default.
• W4386423929 cites W2805193585 @default.
• W4386423929 cites W2953519286 @default.
• W4386423929 cites W2966325970 @default.
• W4386423929 cites W2987683038 @default.
• W4386423929 cites W3001499110 @default.
• W4386423929 cites W3015361071 @default.
• W4386423929 cites W3115280303 @default.
• W4386423929 cites W3173102326 @default.
• W4386423929 cites W3216088664 @default.
• W4386423929 cites W4205340466 @default.
• W4386423929 cites W4213312280 @default.
• W4386423929 cites W4322762719 @default.
• W4386423929 cites W4327569231 @default.
• W4386423929 doi "https://doi.org/10.1101/2023.09.04.23295012" @default.
• W4386423929 hasPublicationYear "2023" @default.
• W4386423929 type Work @default.
• W4386423929 citedByCount "0" @default.
• W4386423929 crossrefType "posted-content" @default.
• W4386423929 hasAuthorship W4386423929A5023451391 @default.
• W4386423929 hasAuthorship W4386423929A5065109936 @default.
• W4386423929 hasAuthorship W4386423929A5065973289 @default.
• W4386423929 hasAuthorship W4386423929A5070165545 @default.
• W4386423929 hasAuthorship W4386423929A5078953009 @default.
• W4386423929 hasBestOaLocation W43864239291 @default.
• W4386423929 hasConcept C111919701 @default.
• W4386423929 hasConcept C112930515 @default.
• W4386423929 hasConcept C126322002 @default.
• W4386423929 hasConcept C144133560 @default.
• W4386423929 hasConcept C160735492 @default.
• W4386423929 hasConcept C162324750 @default.
• W4386423929 hasConcept C162853370 @default.
• W4386423929 hasConcept C164624739 @default.
• W4386423929 hasConcept C21333345 @default.
• W4386423929 hasConcept C2779703844 @default.
• W4386423929 hasConcept C2780560020 @default.
• W4386423929 hasConcept C2780673598 @default.
• W4386423929 hasConcept C41008148 @default.
• W4386423929 hasConcept C50522688 @default.
• W4386423929 hasConcept C71924100 @default.
• W4386423929 hasConcept C98045186 @default.
• W4386423929 hasConceptScore W4386423929C111919701 @default.
• W4386423929 hasConceptScore W4386423929C112930515 @default.
• W4386423929 hasConceptScore W4386423929C126322002 @default.
• W4386423929 hasConceptScore W4386423929C144133560 @default.
• W4386423929 hasConceptScore W4386423929C160735492 @default.
• W4386423929 hasConceptScore W4386423929C162324750 @default.
• W4386423929 hasConceptScore W4386423929C162853370 @default.
• W4386423929 hasConceptScore W4386423929C164624739 @default.
• W4386423929 hasConceptScore W4386423929C21333345 @default.
• W4386423929 hasConceptScore W4386423929C2779703844 @default.
• W4386423929 hasConceptScore W4386423929C2780560020 @default.
• W4386423929 hasConceptScore W4386423929C2780673598 @default.
• W4386423929 hasConceptScore W4386423929C41008148 @default.
• W4386423929 hasConceptScore W4386423929C50522688 @default.
• W4386423929 hasConceptScore W4386423929C71924100 @default.
• W4386423929 hasConceptScore W4386423929C98045186 @default.
• W4386423929 hasLocation W43864239291 @default.
• W4386423929 hasOpenAccess W4386423929 @default.
• W4386423929 hasPrimaryLocation W43864239291 @default.
• W4386423929 hasRelatedWork W1967034197 @default.
• W4386423929 hasRelatedWork W2036021480 @default.
• W4386423929 hasRelatedWork W2341734247 @default.
• W4386423929 hasRelatedWork W2381272187 @default.
• W4386423929 hasRelatedWork W2606446052 @default.
• W4386423929 hasRelatedWork W2738165978 @default.
• W4386423929 hasRelatedWork W2906514884 @default.
• W4386423929 hasRelatedWork W3168495639 @default.
• W4386423929 hasRelatedWork W4229850741 @default.
• W4386423929 hasRelatedWork W4311341135 @default.
• W4386423929 isParatext "false" @default.
• W4386423929 isRetracted "false" @default.
• W4386423929 workType "article" @default.