Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386439189> ?p ?o ?g. }
- W4386439189 endingPage "10" @default.
- W4386439189 startingPage "1" @default.
- W4386439189 abstract "Aim We aimed to investigate the relationship between the peripheral lymphocyte subset frequency and thymectomy in patients with myasthenia gravis (MG).Materials and Methods The frequencies of regulatory B (Breg) and regulatory T (Treg) cells in peripheral blood samples obtained from 69 patients with MG and 10 healthy controls were analyzed using flow cytometry. Serum acetylcholine receptor antibodies (AchR-Ab) were measured. Patients with MG were subdivided into pre-thymectomy, post-thymectomy, and normal thymus control group.Results The percentage of Breg cells was significantly decreased in both the pre-thymectomy (7.92 ± 1.30%) and post-thymectomy (8.14 ± 1.34%) groups compared to healthy controls (16.02 ± 2.78%) and reduced in the acute phase compared to stable maintenance. The proportion of cluster of differentiation (CD) 4 + CD25 + T cells and CD4 + CD25 + CD127low/- Treg cells in MG patients were not significantly different than healthy controls. AchR-Ab titers in aggravating or recurrence patients after thymectomy were significantly higher than that of the stable remission patients (11.13 ± 0.70 and 6.03 ± 0.85 nmol/L, respectively; P < 0.001).Conclusion The frequency of Breg cells may serve as a potential indicator of MG prognosis, while Treg cell frequency did not demonstrate the same prognostic ability. The concentration of AchR-Ab can be used as a dynamic monitoring index of disease severity in patients with MG." @default.
- W4386439189 created "2023-09-06" @default.
- W4386439189 creator A5009130007 @default.
- W4386439189 creator A5026327490 @default.
- W4386439189 creator A5031150824 @default.
- W4386439189 creator A5053653726 @default.
- W4386439189 creator A5082736053 @default.
- W4386439189 date "2023-09-09" @default.
- W4386439189 modified "2023-10-16" @default.
- W4386439189 title "Effect of thymectomy on the frequencies of peripheral regulatory B and T lymphocytes in patients with Myasthenia gravis-a pilot study" @default.
- W4386439189 cites W1607030948 @default.
- W4386439189 cites W1844780367 @default.
- W4386439189 cites W1975473285 @default.
- W4386439189 cites W1978011938 @default.
- W4386439189 cites W1978262930 @default.
- W4386439189 cites W1979094030 @default.
- W4386439189 cites W2005288269 @default.
- W4386439189 cites W2006236831 @default.
- W4386439189 cites W2033335112 @default.
- W4386439189 cites W2041614720 @default.
- W4386439189 cites W2056748835 @default.
- W4386439189 cites W2070834798 @default.
- W4386439189 cites W2109351747 @default.
- W4386439189 cites W2122722718 @default.
- W4386439189 cites W2274176326 @default.
- W4386439189 cites W2293516471 @default.
- W4386439189 cites W2358247423 @default.
- W4386439189 cites W2464935177 @default.
- W4386439189 cites W2589220110 @default.
- W4386439189 cites W2598341361 @default.
- W4386439189 cites W2612069402 @default.
- W4386439189 cites W2622000499 @default.
- W4386439189 cites W2753961976 @default.
- W4386439189 cites W2789644345 @default.
- W4386439189 cites W2793970919 @default.
- W4386439189 cites W2808296583 @default.
- W4386439189 cites W2894158526 @default.
- W4386439189 cites W2901628691 @default.
- W4386439189 cites W2909823939 @default.
- W4386439189 cites W2911339460 @default.
- W4386439189 cites W2969738595 @default.
- W4386439189 cites W2998438632 @default.
- W4386439189 cites W3005483243 @default.
- W4386439189 cites W3008716681 @default.
- W4386439189 cites W3013029036 @default.
- W4386439189 cites W3025033783 @default.
- W4386439189 cites W3094785429 @default.
- W4386439189 cites W3111799889 @default.
- W4386439189 cites W3153446282 @default.
- W4386439189 cites W3162298950 @default.
- W4386439189 cites W3165482046 @default.
- W4386439189 cites W3168850676 @default.
- W4386439189 cites W4200284493 @default.
- W4386439189 cites W4211188347 @default.
- W4386439189 cites W4220660725 @default.
- W4386439189 cites W4225659791 @default.
- W4386439189 cites W4252493259 @default.
- W4386439189 cites W4322630782 @default.
- W4386439189 doi "https://doi.org/10.1080/00207454.2023.2254922" @default.
- W4386439189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37668142" @default.
- W4386439189 hasPublicationYear "2023" @default.
- W4386439189 type Work @default.
- W4386439189 citedByCount "0" @default.
- W4386439189 crossrefType "journal-article" @default.
- W4386439189 hasAuthorship W4386439189A5009130007 @default.
- W4386439189 hasAuthorship W4386439189A5026327490 @default.
- W4386439189 hasAuthorship W4386439189A5031150824 @default.
- W4386439189 hasAuthorship W4386439189A5053653726 @default.
- W4386439189 hasAuthorship W4386439189A5082736053 @default.
- W4386439189 hasConcept C126322002 @default.
- W4386439189 hasConcept C134018914 @default.
- W4386439189 hasConcept C203014093 @default.
- W4386439189 hasConcept C2776090121 @default.
- W4386439189 hasConcept C2777761686 @default.
- W4386439189 hasConcept C2778105408 @default.
- W4386439189 hasConcept C2779615886 @default.
- W4386439189 hasConcept C46762472 @default.
- W4386439189 hasConcept C553184892 @default.
- W4386439189 hasConcept C71924100 @default.
- W4386439189 hasConcept C79484868 @default.
- W4386439189 hasConcept C8891405 @default.
- W4386439189 hasConcept C90924648 @default.
- W4386439189 hasConceptScore W4386439189C126322002 @default.
- W4386439189 hasConceptScore W4386439189C134018914 @default.
- W4386439189 hasConceptScore W4386439189C203014093 @default.
- W4386439189 hasConceptScore W4386439189C2776090121 @default.
- W4386439189 hasConceptScore W4386439189C2777761686 @default.
- W4386439189 hasConceptScore W4386439189C2778105408 @default.
- W4386439189 hasConceptScore W4386439189C2779615886 @default.
- W4386439189 hasConceptScore W4386439189C46762472 @default.
- W4386439189 hasConceptScore W4386439189C553184892 @default.
- W4386439189 hasConceptScore W4386439189C71924100 @default.
- W4386439189 hasConceptScore W4386439189C79484868 @default.
- W4386439189 hasConceptScore W4386439189C8891405 @default.
- W4386439189 hasConceptScore W4386439189C90924648 @default.
- W4386439189 hasFunder F4320321001 @default.
- W4386439189 hasLocation W43864391891 @default.
- W4386439189 hasLocation W43864391892 @default.