FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386470816> ?p ?o ?g. }

• W4386470816 abstract "Abstract Background: Prediction of stroke is indispensable for the initiation of the necessary preventive and prophylactic measures. The conspicuous omission of African data in most of the validated prediction models questions their appropriateness for the region. This study therefore aimed to develop an inclusive and cost-effective Afrocentric predictive model for stroke (CAPMS). Methods and Analyses: We employed an evidence synthesis approach namely meta-analysis structured as per the Preferred Reporting Item for Systematic Reviews and Meta-analyses (PRISMA) guidelines. We searched PubMed, Scopus, African Journals, Medline, Cochrane Library, Web of Science and Cumulative Index for Nursing and Allied Health Literature, from inception to date. Case-control and cohort studies that reported the risk factors of stroke and corresponding risk estimates were included. Screening of the titles and abstracts was undertaken by two independent reviewers. We conducted meta-analyses using Comprehensive Meta-analysis (CMA) version 3. Result: Majority of the eligible studies (>50%) investigated both ischemic and haemorrhagic stroke. In Africa, more than 20 risk factors of stroke were identified however only 18 met the eligibility for meta-analysis. Our findings shows that homocysteine (Rw = 13.9, Ri = 0.67), hypertension (Rw = 5.6, Ri =0.94) and cardiac events (Rw =3.1, Ri = 0.8) were the three most powerful independent predictors of stroke in Africa. Low consumption of green vegetables (Rw =2.4, Ri = 1.0), stress (Rw = 1.76, Ri =1.0) and hypertension were the most clinically responsive risk factors of stroke. All biomarkers except homocysteine were cost-effective having an investigative price of less than $13.6. Critical risk point was fitted at the 90 th percentile being 12.7. The cumulative Rw and investigative costs of CAPMS 1 (15.8 and $2.4) and CAPMS 2 (14.9 and $7.2) showed good performance index and cost-effectiveness. Conclusion: Targeted screening with the CAPMS 1 & CAPMS 2 model represents cost-effective innovation in practice of stroke screening in African clinics and communities. We recommend immediate validation of CAPMS to ascertain its performance, feasibility and acceptability in the region. Registration: The study protocol is registered with PROSPERO (ID: CRD42023430437)." @default.
• W4386470816 created "2023-09-07" @default.
• W4386470816 creator A5004970752 @default.
• W4386470816 creator A5029729499 @default.
• W4386470816 creator A5030654133 @default.
• W4386470816 creator A5092761962 @default.
• W4386470816 creator A5092761963 @default.
• W4386470816 creator A5092761964 @default.
• W4386470816 date "2023-09-06" @default.
• W4386470816 modified "2023-09-27" @default.
• W4386470816 title "Development of an inclusive and cost-effective Afrocentric predictive model for stroke: A novel approach" @default.
• W4386470816 cites W1498763568 @default.
• W4386470816 cites W1592156361 @default.
• W4386470816 cites W1964347831 @default.
• W4386470816 cites W197402492 @default.
• W4386470816 cites W1974671160 @default.
• W4386470816 cites W1976482369 @default.
• W4386470816 cites W1979423827 @default.
• W4386470816 cites W1987799813 @default.
• W4386470816 cites W2007059480 @default.
• W4386470816 cites W2009914361 @default.
• W4386470816 cites W2017176703 @default.
• W4386470816 cites W2029059557 @default.
• W4386470816 cites W2033465810 @default.
• W4386470816 cites W2037406584 @default.
• W4386470816 cites W2039789942 @default.
• W4386470816 cites W2047253785 @default.
• W4386470816 cites W2050875632 @default.
• W4386470816 cites W2055838663 @default.
• W4386470816 cites W2061666549 @default.
• W4386470816 cites W2071881656 @default.
• W4386470816 cites W2081717725 @default.
• W4386470816 cites W2088657398 @default.
• W4386470816 cites W2092413892 @default.
• W4386470816 cites W2096807144 @default.
• W4386470816 cites W2099473815 @default.
• W4386470816 cites W2106210259 @default.
• W4386470816 cites W2107165713 @default.
• W4386470816 cites W2114678398 @default.
• W4386470816 cites W2118748875 @default.
• W4386470816 cites W2119283338 @default.
• W4386470816 cites W2126874967 @default.
• W4386470816 cites W2130373423 @default.
• W4386470816 cites W2144755725 @default.
• W4386470816 cites W2157622195 @default.
• W4386470816 cites W2161374186 @default.
• W4386470816 cites W2162318031 @default.
• W4386470816 cites W2162823371 @default.
• W4386470816 cites W2169160283 @default.
• W4386470816 cites W2169398944 @default.
• W4386470816 cites W2287753527 @default.
• W4386470816 cites W2337004113 @default.
• W4386470816 cites W2354093011 @default.
• W4386470816 cites W2406453816 @default.
• W4386470816 cites W2463406035 @default.
• W4386470816 cites W2519488819 @default.
• W4386470816 cites W2590238230 @default.
• W4386470816 cites W2600140572 @default.
• W4386470816 cites W2604459030 @default.
• W4386470816 cites W2615018142 @default.
• W4386470816 cites W2790387497 @default.
• W4386470816 cites W2805060832 @default.
• W4386470816 cites W2884485392 @default.
• W4386470816 cites W2885057478 @default.
• W4386470816 cites W2890658181 @default.
• W4386470816 cites W2891218961 @default.
• W4386470816 cites W2902661305 @default.
• W4386470816 cites W2972144420 @default.
• W4386470816 cites W2983155694 @default.
• W4386470816 cites W3007596355 @default.
• W4386470816 cites W3007986564 @default.
• W4386470816 cites W3009171849 @default.
• W4386470816 cites W3012162348 @default.
• W4386470816 cites W3014272295 @default.
• W4386470816 cites W3045212462 @default.
• W4386470816 cites W3095073192 @default.
• W4386470816 cites W3097475949 @default.
• W4386470816 cites W3116436676 @default.
• W4386470816 cites W3159119239 @default.
• W4386470816 cites W3196837206 @default.
• W4386470816 cites W3197450290 @default.
• W4386470816 cites W3200469092 @default.
• W4386470816 cites W3200505596 @default.
• W4386470816 cites W4205696255 @default.
• W4386470816 cites W4223987939 @default.
• W4386470816 cites W4224462525 @default.
• W4386470816 cites W4226484122 @default.
• W4386470816 cites W4281668752 @default.
• W4386470816 cites W4297918764 @default.
• W4386470816 cites W4305041694 @default.
• W4386470816 cites W4323567927 @default.
• W4386470816 cites W4323971822 @default.
• W4386470816 cites W4382583256 @default.
• W4386470816 cites W586702243 @default.
• W4386470816 cites W806929814 @default.
• W4386470816 doi "https://doi.org/10.21203/rs.3.rs-3319744/v1" @default.
• W4386470816 hasPublicationYear "2023" @default.
• W4386470816 type Work @default.
• W4386470816 citedByCount "0" @default.
• W4386470816 crossrefType "posted-content" @default.

• next