FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386475192> ?p ?o ?g. }

• W4386475192 abstract "Introduction: The occurrence of fatty liver disease, resulting from the accumulation of excessive fat within the liver, has been showing a significant and rapid increase. This study aimed to evaluate the therapeutic effects of Cheong-sang-bang-pung-san extract (CB) on fatty liver disease, and to elucidate the underlying mechanisms. Methods: We used a high-fat diet (HFD)-fed fatty liver mice and free fatty acid (FFA) induced HepG2 cell lipid accumulation model. The levels of serum, hepatic, and intracellular lipid content were assessed. Histopathological staining was used to evaluate the extent of hepatic lipid accumulation. Real-time polymerase chain reaction and Western blotting were conducted to examine the expression of factors associated with lipid metabolism. Results: We demonstrated that treatment with CB dramatically reduced body weight, liver weight, and fat mass, and improved the serum and hepatic lipid profiles in HFD-induced fatty liver mice. Additionally, CB alleviated lipid accumulation in HFD-fed mice by controlling lipid metabolism, including fatty acid uptake, triglyceride and cholesterol synthesis, and fatty acid oxidation, at the mRNA as well as protein levels. In free fatty acid-treated HepG2 cells, CB significantly reduced intracellular lipid accumulation by regulating lipid metabolism via the activation of AMP-activated protein kinase. Conclusion: These findings provide insights into the mechanisms underlying CB's effects on liver steatosis and position of CB as a potential therapeutic candidate for managing lipid metabolic disorders." @default.
• W4386475192 created "2023-09-07" @default.
• W4386475192 creator A5014406566 @default.
• W4386475192 creator A5028043768 @default.
• W4386475192 creator A5051673722 @default.
• W4386475192 creator A5060939036 @default.
• W4386475192 creator A5086865908 @default.
• W4386475192 creator A5091615384 @default.
• W4386475192 date "2023-09-06" @default.
• W4386475192 modified "2023-09-27" @default.
• W4386475192 title "Cheong-sang-bang-pung-san alleviated hepatic lipid accumulation by regulating lipid metabolism in vitro and in vivo" @default.
• W4386475192 cites W1563676220 @default.
• W4386475192 cites W1967436618 @default.
• W4386475192 cites W2037918682 @default.
• W4386475192 cites W2060082550 @default.
• W4386475192 cites W2066839216 @default.
• W4386475192 cites W2079722537 @default.
• W4386475192 cites W2093873789 @default.
• W4386475192 cites W2200486486 @default.
• W4386475192 cites W2282063661 @default.
• W4386475192 cites W2460134072 @default.
• W4386475192 cites W2462514513 @default.
• W4386475192 cites W2579730125 @default.
• W4386475192 cites W2766550174 @default.
• W4386475192 cites W2782983578 @default.
• W4386475192 cites W2788261792 @default.
• W4386475192 cites W2793601659 @default.
• W4386475192 cites W2810629608 @default.
• W4386475192 cites W2901047569 @default.
• W4386475192 cites W2904733442 @default.
• W4386475192 cites W2926238337 @default.
• W4386475192 cites W2944694507 @default.
• W4386475192 cites W2972451303 @default.
• W4386475192 cites W2996194056 @default.
• W4386475192 cites W2996714785 @default.
• W4386475192 cites W3016191169 @default.
• W4386475192 cites W3028371019 @default.
• W4386475192 cites W3043179056 @default.
• W4386475192 cites W3049282620 @default.
• W4386475192 cites W3135570891 @default.
• W4386475192 cites W3169209367 @default.
• W4386475192 cites W3210113611 @default.
• W4386475192 cites W4220721948 @default.
• W4386475192 cites W4223996199 @default.
• W4386475192 cites W4229369933 @default.
• W4386475192 cites W4283748169 @default.
• W4386475192 cites W4284706566 @default.
• W4386475192 cites W4285091180 @default.
• W4386475192 cites W4289521847 @default.
• W4386475192 cites W4293222079 @default.
• W4386475192 cites W4296333906 @default.
• W4386475192 cites W4316037992 @default.
• W4386475192 doi "https://doi.org/10.3389/fphar.2023.1223534" @default.
• W4386475192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37745047" @default.
• W4386475192 hasPublicationYear "2023" @default.
• W4386475192 type Work @default.
• W4386475192 citedByCount "0" @default.
• W4386475192 crossrefType "journal-article" @default.
• W4386475192 hasAuthorship W4386475192A5014406566 @default.
• W4386475192 hasAuthorship W4386475192A5028043768 @default.
• W4386475192 hasAuthorship W4386475192A5051673722 @default.
• W4386475192 hasAuthorship W4386475192A5060939036 @default.
• W4386475192 hasAuthorship W4386475192A5086865908 @default.
• W4386475192 hasAuthorship W4386475192A5091615384 @default.
• W4386475192 hasBestOaLocation W43864751921 @default.
• W4386475192 hasConcept C126322002 @default.
• W4386475192 hasConcept C134018914 @default.
• W4386475192 hasConcept C150903083 @default.
• W4386475192 hasConcept C185592680 @default.
• W4386475192 hasConcept C207001950 @default.
• W4386475192 hasConcept C25095133 @default.
• W4386475192 hasConcept C2776175330 @default.
• W4386475192 hasConcept C2776991927 @default.
• W4386475192 hasConcept C2778163477 @default.
• W4386475192 hasConcept C2778772119 @default.
• W4386475192 hasConcept C2778913445 @default.
• W4386475192 hasConcept C2779134260 @default.
• W4386475192 hasConcept C4733338 @default.
• W4386475192 hasConcept C48289651 @default.
• W4386475192 hasConcept C543025807 @default.
• W4386475192 hasConcept C55493867 @default.
• W4386475192 hasConcept C71924100 @default.
• W4386475192 hasConcept C86803240 @default.
• W4386475192 hasConceptScore W4386475192C126322002 @default.
• W4386475192 hasConceptScore W4386475192C134018914 @default.
• W4386475192 hasConceptScore W4386475192C150903083 @default.
• W4386475192 hasConceptScore W4386475192C185592680 @default.
• W4386475192 hasConceptScore W4386475192C207001950 @default.
• W4386475192 hasConceptScore W4386475192C25095133 @default.
• W4386475192 hasConceptScore W4386475192C2776175330 @default.
• W4386475192 hasConceptScore W4386475192C2776991927 @default.
• W4386475192 hasConceptScore W4386475192C2778163477 @default.
• W4386475192 hasConceptScore W4386475192C2778772119 @default.
• W4386475192 hasConceptScore W4386475192C2778913445 @default.
• W4386475192 hasConceptScore W4386475192C2779134260 @default.
• W4386475192 hasConceptScore W4386475192C4733338 @default.
• W4386475192 hasConceptScore W4386475192C48289651 @default.
• W4386475192 hasConceptScore W4386475192C543025807 @default.
• W4386475192 hasConceptScore W4386475192C55493867 @default.
• W4386475192 hasConceptScore W4386475192C71924100 @default.

• next