Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386475364> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4386475364 endingPage "348" @default.
- W4386475364 startingPage "337" @default.
- W4386475364 abstract "The first week of gestation is a period of major pregnancy loss in cattle, this study reveals that the male plays a key role in regulating embryonic development during this time.The impact of sire on preimplantation embryonic development in cattle remains poorly understood. This study evaluated differences in embryos produced in vitro from sires with varying capacities to produce blastocysts. Sires classified as high (HP) and low performing (LP) based on their ability to produce embryos were used to better understand how sire regulates embryonic development. By monitoring development, it was determined that the most common arrest stage was the five- to six-cell stage. Embryos (four to six cells) from HP and LP sires were then analyzed for autophagic activity, where embryos for LP sires exhibited increased autophagy than HP-derived embryos. Transcriptome analysis of four-cell embryos found that embryos from LP sires might have issues in sperm mitochondrial clearance, histone retention, and DNA damage, while HP sires had increased expression of genes involved in transcription, chromosome segregation, and cell division. In conclusion, LP sires had an increased proportion of embryos arresting at the five- to six-cell stage, and these embryos had higher rates of cellular stress due to paternal contributions from the spermatozoon." @default.
- W4386475364 created "2023-09-07" @default.
- W4386475364 creator A5002144197 @default.
- W4386475364 creator A5028438754 @default.
- W4386475364 creator A5050988587 @default.
- W4386475364 creator A5060701088 @default.
- W4386475364 creator A5067428228 @default.
- W4386475364 creator A5076315257 @default.
- W4386475364 date "2023-09-06" @default.
- W4386475364 modified "2023-10-18" @default.
- W4386475364 title "Sire modulates developmental kinetics and transcriptome of the bovine embryo" @default.
- W4386475364 doi "https://doi.org/10.1530/rep-23-0030" @default.
- W4386475364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37672361" @default.
- W4386475364 hasPublicationYear "2023" @default.
- W4386475364 type Work @default.
- W4386475364 citedByCount "1" @default.
- W4386475364 crossrefType "journal-article" @default.
- W4386475364 hasAuthorship W4386475364A5002144197 @default.
- W4386475364 hasAuthorship W4386475364A5028438754 @default.
- W4386475364 hasAuthorship W4386475364A5050988587 @default.
- W4386475364 hasAuthorship W4386475364A5060701088 @default.
- W4386475364 hasAuthorship W4386475364A5067428228 @default.
- W4386475364 hasAuthorship W4386475364A5076315257 @default.
- W4386475364 hasConcept C104317684 @default.
- W4386475364 hasConcept C140793950 @default.
- W4386475364 hasConcept C145103041 @default.
- W4386475364 hasConcept C150194340 @default.
- W4386475364 hasConcept C162317418 @default.
- W4386475364 hasConcept C16685009 @default.
- W4386475364 hasConcept C196843134 @default.
- W4386475364 hasConcept C2780284631 @default.
- W4386475364 hasConcept C28748434 @default.
- W4386475364 hasConcept C54355233 @default.
- W4386475364 hasConcept C71924100 @default.
- W4386475364 hasConcept C86803240 @default.
- W4386475364 hasConcept C87073359 @default.
- W4386475364 hasConcept C95444343 @default.
- W4386475364 hasConceptScore W4386475364C104317684 @default.
- W4386475364 hasConceptScore W4386475364C140793950 @default.
- W4386475364 hasConceptScore W4386475364C145103041 @default.
- W4386475364 hasConceptScore W4386475364C150194340 @default.
- W4386475364 hasConceptScore W4386475364C162317418 @default.
- W4386475364 hasConceptScore W4386475364C16685009 @default.
- W4386475364 hasConceptScore W4386475364C196843134 @default.
- W4386475364 hasConceptScore W4386475364C2780284631 @default.
- W4386475364 hasConceptScore W4386475364C28748434 @default.
- W4386475364 hasConceptScore W4386475364C54355233 @default.
- W4386475364 hasConceptScore W4386475364C71924100 @default.
- W4386475364 hasConceptScore W4386475364C86803240 @default.
- W4386475364 hasConceptScore W4386475364C87073359 @default.
- W4386475364 hasConceptScore W4386475364C95444343 @default.
- W4386475364 hasIssue "5" @default.
- W4386475364 hasLocation W43864753641 @default.
- W4386475364 hasLocation W43864753642 @default.
- W4386475364 hasOpenAccess W4386475364 @default.
- W4386475364 hasPrimaryLocation W43864753641 @default.
- W4386475364 hasRelatedWork W1497392423 @default.
- W4386475364 hasRelatedWork W154629941 @default.
- W4386475364 hasRelatedWork W1970994588 @default.
- W4386475364 hasRelatedWork W2033181992 @default.
- W4386475364 hasRelatedWork W2043442474 @default.
- W4386475364 hasRelatedWork W2071465406 @default.
- W4386475364 hasRelatedWork W2474902137 @default.
- W4386475364 hasRelatedWork W4251793284 @default.
- W4386475364 hasRelatedWork W4308662207 @default.
- W4386475364 hasRelatedWork W4386773234 @default.
- W4386475364 hasVolume "166" @default.
- W4386475364 isParatext "false" @default.
- W4386475364 isRetracted "false" @default.
- W4386475364 workType "article" @default.