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- W4386475783 endingPage "2824" @default.
- W4386475783 startingPage "2824" @default.
- W4386475783 abstract "The gastrointestinal ecosystem involves interactions between the host, gut microbiota, and external environment. To colonize the gut of poultry, Salmonella must surmount barriers levied by the intestine including mucosal innate immune responses and microbiota-mediated niche restrictions. Accordingly, comprehending Salmonella intestinal colonization in poultry requires an understanding of how the pathogen interacts with the intestinal ecosystem. In chickens, the paratyphoid Salmonella have evolved the capacity to survive the initial immune response and persist in the avian ceca for months without triggering clinical signs. The persistence of a Salmonella infection in the avian host involves both host defenses and tolerogenic defense strategies. The initial phase of the Salmonella–gut ecosystem interaction is characteristically an innate pro-inflammatory response that controls bacterial invasion. The second phase is initiated by an expansion of the T regulatory cell population in the cecum of Salmonella-infected chickens accompanied by well-defined shifts in the enteric neuro-immunometabolic pathways that changes the local phenotype from pro-inflammatory to an anti-inflammatory environment. Thus, paratyphoid Salmonella in chickens have evolved a unique survival strategy that minimizes the inflammatory response (disease resistance) during the initial infection and then induces an immunometabolic reprogramming in the cecum that alters the host defense to disease tolerance that provides an environment conducive to drive asymptomatic carriage of the bacterial pathogen." @default.
- W4386475783 created "2023-09-07" @default.
- W4386475783 creator A5026650367 @default.
- W4386475783 creator A5060319629 @default.
- W4386475783 date "2023-09-06" @default.
- W4386475783 modified "2023-10-17" @default.
- W4386475783 title "Phenotype Alterations in the Cecal Ecosystem Involved in the Asymptomatic Intestinal Persistence of Paratyphoid Salmonella in Chickens" @default.
- W4386475783 cites W1820286576 @default.
- W4386475783 cites W1902150932 @default.
- W4386475783 cites W1964906621 @default.
- W4386475783 cites W1984140961 @default.
- W4386475783 cites W1985160601 @default.
- W4386475783 cites W1993310127 @default.
- W4386475783 cites W2003769409 @default.
- W4386475783 cites W2004647205 @default.
- W4386475783 cites W2006263017 @default.
- W4386475783 cites W2006759559 @default.
- W4386475783 cites W2008042293 @default.
- W4386475783 cites W2012151682 @default.
- W4386475783 cites W2030575582 @default.
- W4386475783 cites W2041550346 @default.
- W4386475783 cites W2054018440 @default.
- W4386475783 cites W2056941041 @default.
- W4386475783 cites W2071873702 @default.
- W4386475783 cites W2071892943 @default.
- W4386475783 cites W2075108197 @default.
- W4386475783 cites W2075822096 @default.
- W4386475783 cites W2077553363 @default.
- W4386475783 cites W2090234656 @default.
- W4386475783 cites W2091377207 @default.
- W4386475783 cites W2111501296 @default.
- W4386475783 cites W2130797695 @default.
- W4386475783 cites W2132859732 @default.
- W4386475783 cites W2163232298 @default.
- W4386475783 cites W2169198714 @default.
- W4386475783 cites W2212094453 @default.
- W4386475783 cites W2235200355 @default.
- W4386475783 cites W2256900578 @default.
- W4386475783 cites W2258076962 @default.
- W4386475783 cites W2279161330 @default.
- W4386475783 cites W2338773685 @default.
- W4386475783 cites W2372515592 @default.
- W4386475783 cites W2404883061 @default.
- W4386475783 cites W2428459559 @default.
- W4386475783 cites W2605113013 @default.
- W4386475783 cites W2725695906 @default.
- W4386475783 cites W2764237164 @default.
- W4386475783 cites W2766323807 @default.
- W4386475783 cites W2772913728 @default.
- W4386475783 cites W2772947478 @default.
- W4386475783 cites W2800593054 @default.
- W4386475783 cites W2807739800 @default.
- W4386475783 cites W2808807104 @default.
- W4386475783 cites W2885627370 @default.
- W4386475783 cites W2895942617 @default.
- W4386475783 cites W2898407592 @default.
- W4386475783 cites W2899381025 @default.
- W4386475783 cites W2911879441 @default.
- W4386475783 cites W2918358697 @default.
- W4386475783 cites W2944864099 @default.
- W4386475783 cites W2946385728 @default.
- W4386475783 cites W2948078074 @default.
- W4386475783 cites W2974914619 @default.
- W4386475783 cites W2999962735 @default.
- W4386475783 cites W3000685758 @default.
- W4386475783 cites W3001211006 @default.
- W4386475783 cites W3011941507 @default.
- W4386475783 cites W3012221351 @default.
- W4386475783 cites W3013964851 @default.
- W4386475783 cites W3035400372 @default.
- W4386475783 cites W3041761773 @default.
- W4386475783 cites W3085692472 @default.
- W4386475783 cites W3092350511 @default.
- W4386475783 cites W3135542415 @default.
- W4386475783 cites W3163618648 @default.
- W4386475783 cites W3171167670 @default.
- W4386475783 cites W3175256745 @default.
- W4386475783 cites W3199439168 @default.
- W4386475783 cites W3206675209 @default.
- W4386475783 cites W3207227005 @default.
- W4386475783 cites W3215011527 @default.
- W4386475783 cites W3215094193 @default.
- W4386475783 cites W3215341439 @default.
- W4386475783 cites W3216266356 @default.
- W4386475783 cites W4200456854 @default.
- W4386475783 cites W4206170836 @default.
- W4386475783 cites W4207047530 @default.
- W4386475783 cites W4210562301 @default.
- W4386475783 cites W4220696355 @default.
- W4386475783 cites W4225582213 @default.
- W4386475783 cites W4281624797 @default.
- W4386475783 cites W4283731849 @default.
- W4386475783 cites W4292117690 @default.
- W4386475783 cites W4306920893 @default.
- W4386475783 cites W4307939670 @default.
- W4386475783 cites W4310958455 @default.
- W4386475783 cites W4312065785 @default.
- W4386475783 doi "https://doi.org/10.3390/ani13182824" @default.