Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386476985> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4386476985 endingPage "5" @default.
- W4386476985 startingPage "5" @default.
- W4386476985 abstract "Worsening heart failure (WHF) represents a critical point in the disease trajectory of heart failure (HF) patients and significantly affects prognosis negatively. WHF is understood to be defined as worsening signs and symptoms of HF requiring intensification of therapies, including escalation of oral diuretics, initiation of intravenous diuretics at an urgent care center or the emergency room, or requiring hospitalization for close monitoring. Currently, no international HF society guidelines provide a standard definition or a therapeutic approach to the management of WHF. Recent evidence suggests that rapid in-hospital initiation of guideline-directed medical therapy and post-discharge optimization with close surveillance lead to improved outcomes. Moreover, the role of intravenous diuretics in treating acute decongestion has been well defined, and addition of carbonic anhydrase inhibitors and sodium-glucose cotransporter-2 inhibitors has shown to augment diuretic efficacy leading to effective decongestion and possibly early discharge. Soluble guanylate cyclase stimulator, vericiguat, has shown promise in the management of HF patients with a reduced ejection fraction after a recent WHF event in addition to optimized medical therapy. In this review, we discuss the evolving definition of WHF, its precipitants and importance, and the current paradigm of management strategies with a focus on soluble guanylate cyclase stimulators." @default.
- W4386476985 created "2023-09-07" @default.
- W4386476985 creator A5022314919 @default.
- W4386476985 creator A5033240915 @default.
- W4386476985 creator A5043744299 @default.
- W4386476985 creator A5075949562 @default.
- W4386476985 date "2023-01-01" @default.
- W4386476985 modified "2023-10-06" @default.
- W4386476985 title "Worsening heart failure and current management strategies with a focus on soluble guanylate cyclase stimulators" @default.
- W4386476985 doi "https://doi.org/10.4103/hfji.hfji_14_23" @default.
- W4386476985 hasPublicationYear "2023" @default.
- W4386476985 type Work @default.
- W4386476985 citedByCount "0" @default.
- W4386476985 crossrefType "journal-article" @default.
- W4386476985 hasAuthorship W4386476985A5022314919 @default.
- W4386476985 hasAuthorship W4386476985A5033240915 @default.
- W4386476985 hasAuthorship W4386476985A5043744299 @default.
- W4386476985 hasAuthorship W4386476985A5075949562 @default.
- W4386476985 hasConcept C126322002 @default.
- W4386476985 hasConcept C142724271 @default.
- W4386476985 hasConcept C164705383 @default.
- W4386476985 hasConcept C177713679 @default.
- W4386476985 hasConcept C181199279 @default.
- W4386476985 hasConcept C185592680 @default.
- W4386476985 hasConcept C2775914622 @default.
- W4386476985 hasConcept C2778198053 @default.
- W4386476985 hasConcept C2779918671 @default.
- W4386476985 hasConcept C2780182762 @default.
- W4386476985 hasConcept C55493867 @default.
- W4386476985 hasConcept C71924100 @default.
- W4386476985 hasConcept C98274493 @default.
- W4386476985 hasConceptScore W4386476985C126322002 @default.
- W4386476985 hasConceptScore W4386476985C142724271 @default.
- W4386476985 hasConceptScore W4386476985C164705383 @default.
- W4386476985 hasConceptScore W4386476985C177713679 @default.
- W4386476985 hasConceptScore W4386476985C181199279 @default.
- W4386476985 hasConceptScore W4386476985C185592680 @default.
- W4386476985 hasConceptScore W4386476985C2775914622 @default.
- W4386476985 hasConceptScore W4386476985C2778198053 @default.
- W4386476985 hasConceptScore W4386476985C2779918671 @default.
- W4386476985 hasConceptScore W4386476985C2780182762 @default.
- W4386476985 hasConceptScore W4386476985C55493867 @default.
- W4386476985 hasConceptScore W4386476985C71924100 @default.
- W4386476985 hasConceptScore W4386476985C98274493 @default.
- W4386476985 hasIssue "1" @default.
- W4386476985 hasLocation W43864769851 @default.
- W4386476985 hasOpenAccess W4386476985 @default.
- W4386476985 hasPrimaryLocation W43864769851 @default.
- W4386476985 hasRelatedWork W1448399282 @default.
- W4386476985 hasRelatedWork W2042266678 @default.
- W4386476985 hasRelatedWork W2046071402 @default.
- W4386476985 hasRelatedWork W2053818104 @default.
- W4386476985 hasRelatedWork W2530391822 @default.
- W4386476985 hasRelatedWork W2809833519 @default.
- W4386476985 hasRelatedWork W2896352189 @default.
- W4386476985 hasRelatedWork W320511385 @default.
- W4386476985 hasRelatedWork W4247718175 @default.
- W4386476985 hasRelatedWork W4249487090 @default.
- W4386476985 hasVolume "1" @default.
- W4386476985 isParatext "false" @default.
- W4386476985 isRetracted "false" @default.
- W4386476985 workType "article" @default.