FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386477051> ?p ?o ?g. }

• W4386477051 abstract "Diabetic kidney disease (DKD) is one of the most severe chronic microvascular complications of diabetes and the leading cause of end-stage kidney disease worldwide. The mechanism of inflammation underlying DKD has been attracting attention over recent years, but effective therapeutic strategies have remained elusive. Niaoduqing (NDQ) granules are one of the most commonly used drugs for the treatment of DKD in China, and it has therapeutic effects against inflammation in DKD. Therefore, the aim of the present analysis was to evaluate the inflammatory response outcomes and safety of NDQ granules for the treatment of DKD. The following databases were searched from their inception to 31st of May 2023 to obtain published accounts of relevant randomized controlled trials: China National Knowledge Infrastructure, China Science and Technology Journal, Wanfang, The Chinese Biomedicine, PubMed, Web of Science and Cochrane Library. The 'risk of bias' evaluation tool produced by the Cochrane Collaboration Handbook was used for evaluating the quality, whereas Revman software (version 5.3) was used for meta-analysis. In total, 16 studies were included into the present study according to criteria, with a total of 1,526 patients. Compared with those in the control group, the results of the meta-analysis revealed that the combination of conventional treatment and NDQ granules may further decrease C-reactive protein [standardized mean difference (SMD), -1.33; 95% confidence interval (CI), -1.76, -0.91; P<0.00001], TNF-α (SMD, -1.90; 95% CI, -2.35,-1.45; P<0.00001) and IL-6 (SMD, -1.72; 95% CI, -2.52,-0.91; P<0.0001) levels, whilst increasing the clinical effective rate (risk ratio, 1.22; 95% CI, 1.14,1.29; P<0.00001), in patients with DKD. In terms of safety, a total of 34 and 39 patients included in the intervention and in the control group, respectively, developed adverse reactions. Results from the present analysis suggest that NDQ granules may be beneficial in suppressing inflammation caused by DKD when used in combination with conventional treatment, potentially guiding future directions in clinical practice. However, further high-quality studies are needed to confirm the anti-inflammation response in the future." @default.
• W4386477051 created "2023-09-07" @default.
• W4386477051 creator A5004325443 @default.
• W4386477051 creator A5059891279 @default.
• W4386477051 creator A5060346957 @default.
• W4386477051 creator A5062938183 @default.
• W4386477051 date "2023-09-06" @default.
• W4386477051 modified "2023-10-12" @default.
• W4386477051 title "Effects of Niaoduqing granules on inflammatory response of diabetic kidney disease: A meta‑analysis" @default.
• W4386477051 cites W1586312337 @default.
• W4386477051 cites W1608200558 @default.
• W4386477051 cites W1974398404 @default.
• W4386477051 cites W1976124390 @default.
• W4386477051 cites W2005164325 @default.
• W4386477051 cites W2024886564 @default.
• W4386477051 cites W2029774820 @default.
• W4386477051 cites W2041531589 @default.
• W4386477051 cites W2085211563 @default.
• W4386477051 cites W2089570845 @default.
• W4386477051 cites W2115034481 @default.
• W4386477051 cites W2123719513 @default.
• W4386477051 cites W2130585857 @default.
• W4386477051 cites W2143820027 @default.
• W4386477051 cites W2156098321 @default.
• W4386477051 cites W2158745632 @default.
• W4386477051 cites W2496778132 @default.
• W4386477051 cites W2516337081 @default.
• W4386477051 cites W2612344359 @default.
• W4386477051 cites W2768497728 @default.
• W4386477051 cites W2781353122 @default.
• W4386477051 cites W2791011305 @default.
• W4386477051 cites W2883001358 @default.
• W4386477051 cites W2883938512 @default.
• W4386477051 cites W2915700009 @default.
• W4386477051 cites W2939222610 @default.
• W4386477051 cites W2939798759 @default.
• W4386477051 cites W2966932477 @default.
• W4386477051 cites W2973094411 @default.
• W4386477051 cites W2981496710 @default.
• W4386477051 cites W2991792334 @default.
• W4386477051 cites W2999140222 @default.
• W4386477051 cites W3005957464 @default.
• W4386477051 cites W3032465091 @default.
• W4386477051 cites W3124235172 @default.
• W4386477051 cites W4283360568 @default.
• W4386477051 cites W4294215472 @default.
• W4386477051 cites W4308620474 @default.
• W4386477051 cites W4312141101 @default.
• W4386477051 doi "https://doi.org/10.3892/etm.2023.12193" @default.
• W4386477051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37745039" @default.
• W4386477051 hasPublicationYear "2023" @default.
• W4386477051 type Work @default.
• W4386477051 citedByCount "0" @default.
• W4386477051 crossrefType "journal-article" @default.
• W4386477051 hasAuthorship W4386477051A5004325443 @default.
• W4386477051 hasAuthorship W4386477051A5059891279 @default.
• W4386477051 hasAuthorship W4386477051A5060346957 @default.
• W4386477051 hasAuthorship W4386477051A5062938183 @default.
• W4386477051 hasBestOaLocation W43864770511 @default.
• W4386477051 hasConcept C102652120 @default.
• W4386477051 hasConcept C126322002 @default.
• W4386477051 hasConcept C134018914 @default.
• W4386477051 hasConcept C168563851 @default.
• W4386477051 hasConcept C2776478404 @default.
• W4386477051 hasConcept C2779134260 @default.
• W4386477051 hasConcept C3020774429 @default.
• W4386477051 hasConcept C44249647 @default.
• W4386477051 hasConcept C555293320 @default.
• W4386477051 hasConcept C556039675 @default.
• W4386477051 hasConcept C71924100 @default.
• W4386477051 hasConcept C90924648 @default.
• W4386477051 hasConcept C95190672 @default.
• W4386477051 hasConceptScore W4386477051C102652120 @default.
• W4386477051 hasConceptScore W4386477051C126322002 @default.
• W4386477051 hasConceptScore W4386477051C134018914 @default.
• W4386477051 hasConceptScore W4386477051C168563851 @default.
• W4386477051 hasConceptScore W4386477051C2776478404 @default.
• W4386477051 hasConceptScore W4386477051C2779134260 @default.
• W4386477051 hasConceptScore W4386477051C3020774429 @default.
• W4386477051 hasConceptScore W4386477051C44249647 @default.
• W4386477051 hasConceptScore W4386477051C555293320 @default.
• W4386477051 hasConceptScore W4386477051C556039675 @default.
• W4386477051 hasConceptScore W4386477051C71924100 @default.
• W4386477051 hasConceptScore W4386477051C90924648 @default.
• W4386477051 hasConceptScore W4386477051C95190672 @default.
• W4386477051 hasIssue "4" @default.
• W4386477051 hasLocation W43864770511 @default.
• W4386477051 hasLocation W43864770512 @default.
• W4386477051 hasOpenAccess W4386477051 @default.
• W4386477051 hasPrimaryLocation W43864770511 @default.
• W4386477051 hasRelatedWork W2189666756 @default.
• W4386477051 hasRelatedWork W2353826010 @default.
• W4386477051 hasRelatedWork W2611523470 @default.
• W4386477051 hasRelatedWork W2747457586 @default.
• W4386477051 hasRelatedWork W3047402069 @default.
• W4386477051 hasRelatedWork W3184554080 @default.
• W4386477051 hasRelatedWork W3210678099 @default.
• W4386477051 hasRelatedWork W4292341104 @default.
• W4386477051 hasRelatedWork W4295278778 @default.
• W4386477051 hasRelatedWork W4310588839 @default.

• next