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- W4386483885 abstract "Background Celiac trunk compression by the median arcuate ligament (MAL) increases the risk of ischemic complications following gastrointestinal surgical procedures. Previous studies suggest increased risk of hepatic artery thrombosis (HAT) in orthotopic liver transplant (OLT) recipients. The aim of this study is to investigate the impact of untreated MAL compression (MAL-C) on biliary complications in OLT. Methods Abdominal Contrast-Enhanced computed tomography was used to classify celiac trunk stenosis by MAL-C. Digital medical records were retrospectively reviewed to extract pre-transplant, transplant and post-transplant data. Patients were divided into two groups: no MAL compression (nMAL-C) and MAL-C. The primary endpoint was the occurrence of biliary complications. Secondary endpoints were HAT and graft survival. Results 305 OLT were performed from 2010 to 2021, of which 219 were included for analysis: 185 (84.5%) patients without and 34 (15.5%) with MAL-C. The incidence of HAT was 5.9% in both groups. Biliary complications were more common in the MAL-C group (35.3% vs. 17.8%, p = 0.035). Graft survival was significantly decreased in patients with MAL-C (p = 0.035). Conclusions MAL-C of the celiac trunk was associated with increased risk of biliary complications and inferior graft survival in OLT patients. These findings highlight the importance of preoperative screening and treatment of MAL in this population." @default.
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- W4386483885 date "2023-09-01" @default.
- W4386483885 modified "2023-09-30" @default.
- W4386483885 title "Celiac Trunk Stenosis By Median Arcuate Ligament In Orthotopic Liver Transplantation: A Potential Hidden Foe To The Biliary Tree" @default.
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- W4386483885 doi "https://doi.org/10.1016/j.hpb.2023.09.007" @default.
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