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- W4386506875 abstract "Priming, a change in the mental processing of a stimulus as a result of prior encounter with a related stimulus, has been observed repeatedly and studied extensively in humans. Yet currently, there is no behavioral model of short-term priming in lab animals, precluding research on the neurobiological basis of priming. Here, we describe an auditory discrimination paradigm for studying response priming in freely moving mice. We find a priming effect in success rate in all mice tested on the task. In contrast, we do not find a priming effect in response times. Compared to non-primed discrimination trials, the addition of incongruent prime stimuli reduces success rate more than congruent prime stimuli, suggesting a cognitive mechanism based on differential interference. The results establish the short-term priming phenomenon in rodents, and the paradigm opens the door to studying the cellular-network basis of priming." @default.
- W4386506875 created "2023-09-08" @default.
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- W4386506875 date "2023-10-01" @default.
- W4386506875 modified "2023-10-10" @default.
- W4386506875 title "Short-term auditory priming in freely-moving mice" @default.
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- W4386506875 doi "https://doi.org/10.1016/j.isci.2023.107847" @default.
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