FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386524741> ?p ?o ?g. }

• W4386524741 abstract "The forces that maintain stable boundaries between closely related groups are poorly characterized in the Fungi . In other organisms prezygotic barriers, such as assortative mating, are sufficient to reinforce local adaptation and prevent hybridization, yet assortative mating and other prezygotic barriers are largely absent in most fungi. Postzygotic barriers, such as large structural changes across the genome, can also maintain lineage segregation through hybrid incompatibility. The role of structural variation in speciation has been well characterized in a wide array of animals and plants, but not in the Fungi , where it may be relatively uncommon. Here, we use a pan-genomic approach in the globally distributed ectomycorrhizal fungus Boletus edulis Bull. with 310 whole genome sequences and 22 newly generated reference genomes to identify whether large genomic changes are necessary to maintain lineage segregation in the presence of ongoing gene flow. In addition, we evaluate the extent to which different lineages possess unique repertories of saprotrophic and effector gene families to determine whether lineages exhibit distinct ecological capacities that contribute toward lineage segregation. We show that B. edulis possesses one of the most diverse pan-genomes of eukaryotes, with the lowest proportion of core proteins identified in the Fungi . Pan-genomic clustering correlates more with geography than with gene flow or phylogenetic relatedness. We also show that structural variation is abundant within B. edulis , but is rarely fixed within a lineage or even shared between two individuals. Moreover, we find that a similar degree of genomic synteny exists between genomes of different lineages as between genomes of the same lineage. Functional protein analysis shows that a new lineage of B. edulis from tropical Guatemala has significant contractions in most saprotrophic gene families and possesses a distinct saprotrophic enzyme repertoire. This lineage also a carries a clear signal of a demographic bottleneck, has very low genome-wide heterozygosity, and an inflated genome size, consistent with a substantial shift in ecological niche. In addition, we reveal preliminary evidence for subtle differences in host preference among European B. edulis . Altogether, our results provide clear evidence that large changes in genome structure or proteome content are not necessary or perhaps even sufficient to maintain long-term lineage fidelity in the presence of ongoing gene flow. Instead, it appears that subtle differences in ecological tendencies can maintain stable boundaries through time." @default.
• W4386524741 created "2023-09-08" @default.
• W4386524741 creator A5004627844 @default.
• W4386524741 creator A5005798183 @default.
• W4386524741 creator A5062156514 @default.
• W4386524741 creator A5070810971 @default.
• W4386524741 creator A5092771496 @default.
• W4386524741 creator A5092771497 @default.
• W4386524741 date "2023-09-07" @default.
• W4386524741 modified "2023-10-16" @default.
• W4386524741 title "From populations to pan-genomes: investigating the role of ecology and genomic architecture in maintaining species boundaries in the porcini mushroom,<i>Boletus edulis</i>" @default.
• W4386524741 doi "https://doi.org/10.1101/2023.09.05.556370" @default.
• W4386524741 hasPublicationYear "2023" @default.
• W4386524741 type Work @default.
• W4386524741 citedByCount "0" @default.
• W4386524741 crossrefType "posted-content" @default.
• W4386524741 hasAuthorship W4386524741A5004627844 @default.
• W4386524741 hasAuthorship W4386524741A5005798183 @default.
• W4386524741 hasAuthorship W4386524741A5062156514 @default.
• W4386524741 hasAuthorship W4386524741A5070810971 @default.
• W4386524741 hasAuthorship W4386524741A5092771496 @default.
• W4386524741 hasAuthorship W4386524741A5092771497 @default.
• W4386524741 hasConcept C104317684 @default.
• W4386524741 hasConcept C107023163 @default.
• W4386524741 hasConcept C141231307 @default.
• W4386524741 hasConcept C193252679 @default.
• W4386524741 hasConcept C2554327 @default.
• W4386524741 hasConcept C2776817793 @default.
• W4386524741 hasConcept C2777433574 @default.
• W4386524741 hasConcept C514575182 @default.
• W4386524741 hasConcept C53702515 @default.
• W4386524741 hasConcept C54355233 @default.
• W4386524741 hasConcept C68873052 @default.
• W4386524741 hasConcept C78458016 @default.
• W4386524741 hasConcept C86803240 @default.
• W4386524741 hasConcept C90132467 @default.
• W4386524741 hasConceptScore W4386524741C104317684 @default.
• W4386524741 hasConceptScore W4386524741C107023163 @default.
• W4386524741 hasConceptScore W4386524741C141231307 @default.
• W4386524741 hasConceptScore W4386524741C193252679 @default.
• W4386524741 hasConceptScore W4386524741C2554327 @default.
• W4386524741 hasConceptScore W4386524741C2776817793 @default.
• W4386524741 hasConceptScore W4386524741C2777433574 @default.
• W4386524741 hasConceptScore W4386524741C514575182 @default.
• W4386524741 hasConceptScore W4386524741C53702515 @default.
• W4386524741 hasConceptScore W4386524741C54355233 @default.
• W4386524741 hasConceptScore W4386524741C68873052 @default.
• W4386524741 hasConceptScore W4386524741C78458016 @default.
• W4386524741 hasConceptScore W4386524741C86803240 @default.
• W4386524741 hasConceptScore W4386524741C90132467 @default.
• W4386524741 hasLocation W43865247411 @default.
• W4386524741 hasOpenAccess W4386524741 @default.
• W4386524741 hasPrimaryLocation W43865247411 @default.
• W4386524741 hasRelatedWork W2130436157 @default.
• W4386524741 hasRelatedWork W2510811827 @default.
• W4386524741 hasRelatedWork W2765286129 @default.
• W4386524741 hasRelatedWork W2794610301 @default.
• W4386524741 hasRelatedWork W2889202427 @default.
• W4386524741 hasRelatedWork W2951426837 @default.
• W4386524741 hasRelatedWork W4229549692 @default.
• W4386524741 hasRelatedWork W4281698698 @default.
• W4386524741 hasRelatedWork W4282974606 @default.
• W4386524741 hasRelatedWork W4321748640 @default.
• W4386524741 isParatext "false" @default.
• W4386524741 isRetracted "false" @default.
• W4386524741 workType "article" @default.