FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386529932> ?p ?o ?g. }

• W4386529932 endingPage "109902" @default.
• W4386529932 startingPage "109902" @default.
• W4386529932 abstract "We aimed to investigate the incidence of lymphoma-related death (LRD) and the long-term net survival benefit of radiotherapy (RT) for early-stage diffuse large B-cell lymphoma (DLBCL) in the rituximab era.10,841 adults diagnosed with early-stage DLBCL between 2002-2015 were retrospectively analyzed using data from the Surveillance, Epidemiology, and End Results database. Primary therapy was categorized into combined-modality treatment (CMT, n = 3,631) and chemotherapy alone (n = 7,210). Competing risk analysis was used to evaluate the cumulative incidence of mortality. Inverse probability of treatment weighting (IPTW) was used to balance groups. The net survival benefit of RT was estimated through relative survival (RS), standardized mortality ratio (SMR), and transformed Cox regression, while controlling for background mortality.Patients initially treated with CMT had a lower cumulative incidence of LRD compared to those who received chemotherapy alone (HR 0.63, 95%CI: 0.57-0.69; P < 0.001). The 10-year overall survival (OS), RS, and SMR for CMT were 66.1%, 85.0%, and 1.71 respectively, which were significantly better than those for chemotherapy alone (53.0%; 69.8%; 2.62; all P < 0.001). IPTW and multivariable analysis revealed that the addition of RT led to better OS (HR 0.67, 95%CI: 0.62-0.71; P < 0.001) and RS (HR 0.69, 95%CI: 0.65-0.74; P < 0.001). Moreover, compared with chemotherapy alone, the benefit of OS and RS for CMT increased over time within 10 years of diagnosis.RT reduced LRD and improved the long-term net survival in early-stage DLBCL in the rituximab era. Further prospective studies are warranted to assess the specific patient population that would benefit the most from consolidative RT in early-stage DLBCL." @default.
• W4386529932 created "2023-09-09" @default.
• W4386529932 creator A5002229860 @default.
• W4386529932 creator A5003322678 @default.
• W4386529932 creator A5006822602 @default.
• W4386529932 creator A5011880298 @default.
• W4386529932 creator A5013104345 @default.
• W4386529932 creator A5021687717 @default.
• W4386529932 creator A5029329731 @default.
• W4386529932 creator A5031810848 @default.
• W4386529932 creator A5033429378 @default.
• W4386529932 creator A5050067556 @default.
• W4386529932 creator A5061434488 @default.
• W4386529932 creator A5067483347 @default.
• W4386529932 creator A5067972777 @default.
• W4386529932 creator A5074516602 @default.
• W4386529932 creator A5077695586 @default.
• W4386529932 creator A5081524222 @default.
• W4386529932 creator A5082156574 @default.
• W4386529932 creator A5084229837 @default.
• W4386529932 creator A5085103682 @default.
• W4386529932 creator A5085744620 @default.
• W4386529932 creator A5088840244 @default.
• W4386529932 date "2023-11-01" @default.
• W4386529932 modified "2023-09-28" @default.
• W4386529932 title "Decreased lymphoma-related deaths and improved long-term relative survival with radiotherapy for early-stage diffuse large B-cell lymphoma in the rituximab era" @default.
• W4386529932 cites W1494281429 @default.
• W4386529932 cites W1577900120 @default.
• W4386529932 cites W1600734675 @default.
• W4386529932 cites W2018071905 @default.
• W4386529932 cites W2022872482 @default.
• W4386529932 cites W2035121892 @default.
• W4386529932 cites W2048470090 @default.
• W4386529932 cites W2050588850 @default.
• W4386529932 cites W2052164658 @default.
• W4386529932 cites W2114299804 @default.
• W4386529932 cites W2130185170 @default.
• W4386529932 cites W2136060045 @default.
• W4386529932 cites W2142844052 @default.
• W4386529932 cites W2144329058 @default.
• W4386529932 cites W2145453495 @default.
• W4386529932 cites W2145566956 @default.
• W4386529932 cites W2152590022 @default.
• W4386529932 cites W2153665789 @default.
• W4386529932 cites W2153706988 @default.
• W4386529932 cites W2161205944 @default.
• W4386529932 cites W2162885909 @default.
• W4386529932 cites W2166337528 @default.
• W4386529932 cites W2167556523 @default.
• W4386529932 cites W2327610290 @default.
• W4386529932 cites W2472520251 @default.
• W4386529932 cites W2475270667 @default.
• W4386529932 cites W2518731208 @default.
• W4386529932 cites W2611767787 @default.
• W4386529932 cites W2766567226 @default.
• W4386529932 cites W2807744826 @default.
• W4386529932 cites W2890444594 @default.
• W4386529932 cites W2924528896 @default.
• W4386529932 cites W2948321946 @default.
• W4386529932 cites W2995669627 @default.
• W4386529932 cites W2999716073 @default.
• W4386529932 cites W3005437019 @default.
• W4386529932 cites W3024199742 @default.
• W4386529932 cites W3041648365 @default.
• W4386529932 cites W3046325641 @default.
• W4386529932 cites W3089264828 @default.
• W4386529932 cites W3133955595 @default.
• W4386529932 cites W3134205746 @default.
• W4386529932 cites W3201743266 @default.
• W4386529932 cites W4200139163 @default.
• W4386529932 cites W4220713945 @default.
• W4386529932 cites W4281912254 @default.
• W4386529932 cites W4292249669 @default.
• W4386529932 doi "https://doi.org/10.1016/j.radonc.2023.109902" @default.
• W4386529932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37678622" @default.
• W4386529932 hasPublicationYear "2023" @default.
• W4386529932 type Work @default.
• W4386529932 citedByCount "0" @default.
• W4386529932 crossrefType "journal-article" @default.
• W4386529932 hasAuthorship W4386529932A5002229860 @default.
• W4386529932 hasAuthorship W4386529932A5003322678 @default.
• W4386529932 hasAuthorship W4386529932A5006822602 @default.
• W4386529932 hasAuthorship W4386529932A5011880298 @default.
• W4386529932 hasAuthorship W4386529932A5013104345 @default.
• W4386529932 hasAuthorship W4386529932A5021687717 @default.
• W4386529932 hasAuthorship W4386529932A5029329731 @default.
• W4386529932 hasAuthorship W4386529932A5031810848 @default.
• W4386529932 hasAuthorship W4386529932A5033429378 @default.
• W4386529932 hasAuthorship W4386529932A5050067556 @default.
• W4386529932 hasAuthorship W4386529932A5061434488 @default.
• W4386529932 hasAuthorship W4386529932A5067483347 @default.
• W4386529932 hasAuthorship W4386529932A5067972777 @default.
• W4386529932 hasAuthorship W4386529932A5074516602 @default.
• W4386529932 hasAuthorship W4386529932A5077695586 @default.
• W4386529932 hasAuthorship W4386529932A5081524222 @default.
• W4386529932 hasAuthorship W4386529932A5082156574 @default.
• W4386529932 hasAuthorship W4386529932A5084229837 @default.
• W4386529932 hasAuthorship W4386529932A5085103682 @default.

• next