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- W4386533470 abstract "Abstract Background: Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease that can be caused by various factors, including postpartum, pregnancy, autoimmune disorders, infections, and coagulation abnormalities. Sjögren's syndrome (SS) is an inflammatory autoimmune disease characterized by lymphocytic infiltration of exocrine glands.We report a case of a 27-year-old female diagnosed with postpartum antiphospholipid antibody syndrome (APS) secondary to SS and accompanied byCVST, subdural haematoma (SDH), intracerebral haemorrhage (ICH), and subarachnoid haemorrhage (SAH). Case presentation: The patient is a 27-year-old female who was diagnosed with APS secondary to SS during pregnancy.She developed headaches 7 days postpartum and experienced seizures along with left-sided limb paralysis on the 9th day.Computed tomography (CT)and magnetic resonance imaging (MRI) scans indicated SDH,ICH and SAH.Magnetic resonance venography (MRV) suggested the formation of venous sinus thrombosis.The patient showed significant improvement after receiving anticoagulants, steroids, and immunosuppressive treatment. Conclusions: The occurrence of APS secondary to SS and simultaneous CVST, along with SAH, ICH, and SDH, is exceedingly rare.However, in patients previously diagnosed with APS who experience neurological deficits, the possibility of CVST should be considered, and MRV examination should be promptly completed.The simultaneous occurrence of intracranial haemorrhage and thrombosis made the treatment of this patient complex. We summarized the pathogenesis, clinical features, treatment, and prognosis of this patient and then performed a literature review to provide clinical practitioners with a reference for the diagnosis and treatment of this disease." @default.
- W4386533470 created "2023-09-09" @default.
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- W4386533470 date "2023-09-08" @default.
- W4386533470 modified "2023-10-16" @default.
- W4386533470 title "Postpartum Antiphospholipid Antibody Syndrome Secondary to Sjögren's Syndrome Accompanied by Cerebral Venous Sinus Thrombosis and Multicompartmental Intracerebral Haemorrhage: A Case Report and Literature Review" @default.
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- W4386533470 doi "https://doi.org/10.21203/rs.3.rs-3321804/v1" @default.
- W4386533470 hasPublicationYear "2023" @default.
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