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• W4386533692 abstract "SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES (SERKs) and NUCLEAR SHUTTLE PROTEIN-INTERACTING KINASES (NIKs) belong to superfamily II of leucine-rich repeat receptor-like kinases, which share cytosolic kinase conservation and a similar ectodomain configuration. SERKs have been extensively demonstrated to function as coreceptors of receptor-like kinases, which sense biotic or developmental signals to initiate specific responses. NIKs, on the other hand, have emerged as downstream components in signaling cascades, not functioning as coreceptors but rather serving as hubs that converge information from both biotic and abiotic signals, resulting in a unified response. Like SERKs, NIKs play a crucial role as information spreaders in plant cells, forming hubs of high centrality. However, unlike SERKs, which function as coreceptors and assemble paired receptor-specific responses, NIKs employ a shared signaling circuit to transduce diverse biotic and abiotic signals into the same physiological response. Therefore, this review highlights the concept of signaling hubs that differ from coreceptors in signaling pathways." @default.
• W4386533692 created "2023-09-09" @default.
• W4386533692 creator A5053543995 @default.
• W4386533692 date "2023-09-01" @default.
• W4386533692 modified "2023-09-30" @default.
• W4386533692 title "SERKs and NIKs: Coreceptors or signaling hubs in a complex crosstalk between growth and defense?" @default.
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• W4386533692 doi "https://doi.org/10.1016/j.pbi.2023.102447" @default.
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