Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386541387> ?p ?o ?g. }
- W4386541387 endingPage "3205" @default.
- W4386541387 startingPage "3205" @default.
- W4386541387 abstract "Starch phosphorylase (PHO) is a pivotal enzyme within the GT35-glycogen-phosphorylase (GT; glycosyltransferases) superfamily. Despite the ongoing debate surrounding the precise role of PHO1, evidence points to its substantial influence on starch biosynthesis, supported by its gene expression profile and subcellular localization. Key to PHO1 function is the enzymatic regulation via phosphorylation; a myriad of such modification sites has been unveiled in model crops. However, the functional implications of these sites remain to be elucidated. In this study, we utilized site-directed mutagenesis on the phosphorylation sites of Zea mays PHO1, replacing serine residues with alanine, glutamic acid, and aspartic acid, to discern the effects of phosphorylation. Our findings indicate that phosphorylation exerts no impact on the stability or localization of PHO1. Nonetheless, our enzymatic assays unveiled a crucial role for phosphorylation at the S566 residue within the L80 region of the PHO1 structure, suggesting a potential modulation or enhancement of PHO1 activity. These data advance our understanding of starch biosynthesis regulation and present potential targets for crop yield optimization." @default.
- W4386541387 created "2023-09-09" @default.
- W4386541387 creator A5013229168 @default.
- W4386541387 creator A5019126465 @default.
- W4386541387 creator A5020369130 @default.
- W4386541387 creator A5036963066 @default.
- W4386541387 creator A5090603786 @default.
- W4386541387 creator A5091044408 @default.
- W4386541387 date "2023-09-08" @default.
- W4386541387 modified "2023-10-14" @default.
- W4386541387 title "Site-Directed Mutations at Phosphorylation Sites in Zea mays PHO1 Reveal Modulation of Enzymatic Activity by Phosphorylation at S566 in the L80 Region" @default.
- W4386541387 cites W1512092650 @default.
- W4386541387 cites W1580022703 @default.
- W4386541387 cites W1917977264 @default.
- W4386541387 cites W1970731456 @default.
- W4386541387 cites W1984521042 @default.
- W4386541387 cites W1989627737 @default.
- W4386541387 cites W1996036897 @default.
- W4386541387 cites W2009019843 @default.
- W4386541387 cites W2024615565 @default.
- W4386541387 cites W2037411784 @default.
- W4386541387 cites W2051157274 @default.
- W4386541387 cites W2051329494 @default.
- W4386541387 cites W2056019273 @default.
- W4386541387 cites W2057920854 @default.
- W4386541387 cites W2061165247 @default.
- W4386541387 cites W2065815146 @default.
- W4386541387 cites W2103502691 @default.
- W4386541387 cites W2114793678 @default.
- W4386541387 cites W2115456426 @default.
- W4386541387 cites W2123427500 @default.
- W4386541387 cites W2124789577 @default.
- W4386541387 cites W2130781871 @default.
- W4386541387 cites W2134955158 @default.
- W4386541387 cites W2139475957 @default.
- W4386541387 cites W2149650186 @default.
- W4386541387 cites W2156690787 @default.
- W4386541387 cites W2165099495 @default.
- W4386541387 cites W2172104619 @default.
- W4386541387 cites W2277370993 @default.
- W4386541387 cites W2398623495 @default.
- W4386541387 cites W2480807373 @default.
- W4386541387 cites W2605925004 @default.
- W4386541387 cites W2610167945 @default.
- W4386541387 cites W2755204399 @default.
- W4386541387 cites W2803152654 @default.
- W4386541387 cites W2903024528 @default.
- W4386541387 cites W2915768764 @default.
- W4386541387 cites W2980137746 @default.
- W4386541387 cites W3088570016 @default.
- W4386541387 cites W3201686389 @default.
- W4386541387 cites W4224245587 @default.
- W4386541387 cites W4281739578 @default.
- W4386541387 cites W4383552618 @default.
- W4386541387 cites W4385811483 @default.
- W4386541387 doi "https://doi.org/10.3390/plants12183205" @default.
- W4386541387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37765369" @default.
- W4386541387 hasPublicationYear "2023" @default.
- W4386541387 type Work @default.
- W4386541387 citedByCount "0" @default.
- W4386541387 crossrefType "journal-article" @default.
- W4386541387 hasAuthorship W4386541387A5013229168 @default.
- W4386541387 hasAuthorship W4386541387A5019126465 @default.
- W4386541387 hasAuthorship W4386541387A5020369130 @default.
- W4386541387 hasAuthorship W4386541387A5036963066 @default.
- W4386541387 hasAuthorship W4386541387A5090603786 @default.
- W4386541387 hasAuthorship W4386541387A5091044408 @default.
- W4386541387 hasBestOaLocation W43865413871 @default.
- W4386541387 hasConcept C104317684 @default.
- W4386541387 hasConcept C11960822 @default.
- W4386541387 hasConcept C161019410 @default.
- W4386541387 hasConcept C181199279 @default.
- W4386541387 hasConcept C185592680 @default.
- W4386541387 hasConcept C204779464 @default.
- W4386541387 hasConcept C2776414213 @default.
- W4386541387 hasConcept C2776879804 @default.
- W4386541387 hasConcept C2779856020 @default.
- W4386541387 hasConcept C515207424 @default.
- W4386541387 hasConcept C55493867 @default.
- W4386541387 hasConcept C86803240 @default.
- W4386541387 hasConcept C87325107 @default.
- W4386541387 hasConcept C95444343 @default.
- W4386541387 hasConcept C97029542 @default.
- W4386541387 hasConceptScore W4386541387C104317684 @default.
- W4386541387 hasConceptScore W4386541387C11960822 @default.
- W4386541387 hasConceptScore W4386541387C161019410 @default.
- W4386541387 hasConceptScore W4386541387C181199279 @default.
- W4386541387 hasConceptScore W4386541387C185592680 @default.
- W4386541387 hasConceptScore W4386541387C204779464 @default.
- W4386541387 hasConceptScore W4386541387C2776414213 @default.
- W4386541387 hasConceptScore W4386541387C2776879804 @default.
- W4386541387 hasConceptScore W4386541387C2779856020 @default.
- W4386541387 hasConceptScore W4386541387C515207424 @default.
- W4386541387 hasConceptScore W4386541387C55493867 @default.
- W4386541387 hasConceptScore W4386541387C86803240 @default.
- W4386541387 hasConceptScore W4386541387C87325107 @default.
- W4386541387 hasConceptScore W4386541387C95444343 @default.
- W4386541387 hasConceptScore W4386541387C97029542 @default.