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- W4386542818 abstract "Acrylamide causes neurotoxicity, reproductive, and developmental disorders and some tumors in animals. The effect of acrylamide on human health is still not fully understood. Determination of hemoglobin products for assessment of exposure to acrylamide is a more widely used method recently. Since people's eating habits are mainly carbohydrates, it is inevitable that acrylamide enters the body with daily nutrition. Chronic regular acrylamide intake will occur with this eating habit. Intermediate metabolites formed during the elimination mechanisms of acrylamide may also be more toxic. This can cause chronic toxicity in the body. There are many studies on chronic exposure in rodents. It has been defined as group 2A carcinogen by the International Agency for Research on Cancer. Two years of studies in rodents have shown that acrylamide causes some tumors such as thyroid, liver, ovary, and breast. Acrylamide levels in foods and exposure in various populations have been extensively studied over the past decade. When considering the health risk assessment of acrylamide, the margin of exposure (MoE) criterion is used as an alternative approach. The Scientific Committee of the European Food Safety Authority declared that there is a health concern among the local population due to the relatively low MoE values. To date, a number of cohort studies involving human exposure to acrylamide in different countries have been conducted and relevant risk assessments for some types of cancer have been obtained. However, all these studies did not provide sufficient evidence of cancer risk in humans with daily dietary acrylamide intake." @default.
- W4386542818 created "2023-09-09" @default.
- W4386542818 creator A5059382397 @default.
- W4386542818 date "2024-01-01" @default.
- W4386542818 modified "2023-10-16" @default.
- W4386542818 title "Acrylamide intake, its effects on tissues and cancer" @default.
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- W4386542818 doi "https://doi.org/10.1016/b978-0-323-99119-3.00077-1" @default.
- W4386542818 hasPublicationYear "2024" @default.
- W4386542818 type Work @default.