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- W4386543176 abstract "Osteoarthritis is characterized by reduced proteoglycan content, irregular collagen arrangement, and increased water content in the articular cartilage matrix from the early stages of the disease. Advanced compositional magnetic resonance imaging (MRI) techniques such as T2 and T1rho mapping unravel the biochemical properties of cartilage. They are currently applied clinically, allowing quantitative assessment of early degenerative changes in articular cartilage before morphological changes in thickness occur. The importance of compositional MRI for diagnosing cartilage-related problems will expectedly increase with developments in preventive medicine and regenerative medicine for cartilage damage. This chapter outlines the characteristics and status of articular cartilage evaluation by T2 mapping and T1rho mapping, two widely validated compositional MRI techniques that are expected to serve as noninvasive biomarkers of cartilage degeneration." @default.
- W4386543176 created "2023-09-09" @default.
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- W4386543176 date "2024-01-01" @default.
- W4386543176 modified "2023-10-16" @default.
- W4386543176 title "Compositional magnetic resonance imaging techniques for the evaluation of knee cartilage" @default.
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- W4386543176 doi "https://doi.org/10.1016/b978-0-323-90597-8.00022-0" @default.
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