Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386544762> ?p ?o ?g. }
- W4386544762 abstract "Oxidative stress caused by free radicals contributes to the pathogenesis of multiple chronic health conditions. Phytochemicals protect against oxidative stress; however, low bioavailability from dietary sources limits their health benefits. This study aimed to assess the effects of anthocyanins and gingerols' combination on the cellular antioxidant response of Caco-2 cells against oxidative stress. A strong synergism was observed for anthocyanin-gingerol (Ac-G) w/w combined ratios of 8:1 and 2:1 (dosages of (1 + 0.125) and (1 + 0.5) μg/mL) in the cellular antioxidant activity (CAA) and cytoprotective effects, with synergistic effect indicator (SE) values of 1.41 and 1.61, respectively. The synergism of Ac-G combinations promoted cellular antioxidant defense systems and cytoprotective effects by reducing the induced GPx enzyme activity, protecting SOD enzyme activity, reducing cellular ROS generation, increasing glutathione content, and inhibiting lipid peroxidation. Thus, Ac-G combinations showed potential in supporting the endogenous antioxidant systems to protect cells from oxidation and restore physiological redox status. The Ac-G formulation is a promising healthy option that can be developed into functional foods or nutraceutical products. Furthermore, it could help address the low bioavailability of these phenolics, as higher effects were achieved when combining the same doses." @default.
- W4386544762 created "2023-09-09" @default.
- W4386544762 creator A5008577871 @default.
- W4386544762 creator A5080464782 @default.
- W4386544762 creator A5085437923 @default.
- W4386544762 date "2023-09-08" @default.
- W4386544762 modified "2023-09-27" @default.
- W4386544762 title "Gingerols synergize with anthocyanins to induce antioxidant activity in vitro" @default.
- W4386544762 cites W138317025 @default.
- W4386544762 cites W1511599028 @default.
- W4386544762 cites W1518976036 @default.
- W4386544762 cites W1524429176 @default.
- W4386544762 cites W1569929138 @default.
- W4386544762 cites W1771843391 @default.
- W4386544762 cites W1876272959 @default.
- W4386544762 cites W1970818338 @default.
- W4386544762 cites W1972009654 @default.
- W4386544762 cites W1973621432 @default.
- W4386544762 cites W1976066635 @default.
- W4386544762 cites W1986112503 @default.
- W4386544762 cites W1991690086 @default.
- W4386544762 cites W2004297939 @default.
- W4386544762 cites W2014126737 @default.
- W4386544762 cites W2047706503 @default.
- W4386544762 cites W2049339166 @default.
- W4386544762 cites W2051146664 @default.
- W4386544762 cites W2054106669 @default.
- W4386544762 cites W2070038006 @default.
- W4386544762 cites W2071393402 @default.
- W4386544762 cites W2081706457 @default.
- W4386544762 cites W2084229951 @default.
- W4386544762 cites W2106145538 @default.
- W4386544762 cites W2120144226 @default.
- W4386544762 cites W2134565629 @default.
- W4386544762 cites W2153394357 @default.
- W4386544762 cites W2164202552 @default.
- W4386544762 cites W2166088043 @default.
- W4386544762 cites W2316478407 @default.
- W4386544762 cites W2327354804 @default.
- W4386544762 cites W2345530657 @default.
- W4386544762 cites W2569232017 @default.
- W4386544762 cites W2603238840 @default.
- W4386544762 cites W2735487846 @default.
- W4386544762 cites W2747068608 @default.
- W4386544762 cites W2767733492 @default.
- W4386544762 cites W2768499679 @default.
- W4386544762 cites W2781218487 @default.
- W4386544762 cites W2783031984 @default.
- W4386544762 cites W2901745793 @default.
- W4386544762 cites W2970987600 @default.
- W4386544762 cites W3204337548 @default.
- W4386544762 cites W3212545342 @default.
- W4386544762 cites W4361027198 @default.
- W4386544762 cites W88937860 @default.
- W4386544762 cites W910418740 @default.
- W4386544762 doi "https://doi.org/10.3389/fnut.2023.1229015" @default.
- W4386544762 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37743923" @default.
- W4386544762 hasPublicationYear "2023" @default.
- W4386544762 type Work @default.
- W4386544762 citedByCount "0" @default.
- W4386544762 crossrefType "journal-article" @default.
- W4386544762 hasAuthorship W4386544762A5008577871 @default.
- W4386544762 hasAuthorship W4386544762A5080464782 @default.
- W4386544762 hasAuthorship W4386544762A5085437923 @default.
- W4386544762 hasBestOaLocation W43865447621 @default.
- W4386544762 hasConcept C17857428 @default.
- W4386544762 hasConcept C181199279 @default.
- W4386544762 hasConcept C181389837 @default.
- W4386544762 hasConcept C185592680 @default.
- W4386544762 hasConcept C2776151105 @default.
- W4386544762 hasConcept C2776573510 @default.
- W4386544762 hasConcept C2778004101 @default.
- W4386544762 hasConcept C2778945092 @default.
- W4386544762 hasConcept C2780829032 @default.
- W4386544762 hasConcept C31903555 @default.
- W4386544762 hasConcept C48349386 @default.
- W4386544762 hasConcept C538909803 @default.
- W4386544762 hasConcept C55493867 @default.
- W4386544762 hasConcept C86803240 @default.
- W4386544762 hasConcept C98274493 @default.
- W4386544762 hasConceptScore W4386544762C17857428 @default.
- W4386544762 hasConceptScore W4386544762C181199279 @default.
- W4386544762 hasConceptScore W4386544762C181389837 @default.
- W4386544762 hasConceptScore W4386544762C185592680 @default.
- W4386544762 hasConceptScore W4386544762C2776151105 @default.
- W4386544762 hasConceptScore W4386544762C2776573510 @default.
- W4386544762 hasConceptScore W4386544762C2778004101 @default.
- W4386544762 hasConceptScore W4386544762C2778945092 @default.
- W4386544762 hasConceptScore W4386544762C2780829032 @default.
- W4386544762 hasConceptScore W4386544762C31903555 @default.
- W4386544762 hasConceptScore W4386544762C48349386 @default.
- W4386544762 hasConceptScore W4386544762C538909803 @default.
- W4386544762 hasConceptScore W4386544762C55493867 @default.
- W4386544762 hasConceptScore W4386544762C86803240 @default.
- W4386544762 hasConceptScore W4386544762C98274493 @default.
- W4386544762 hasLocation W43865447621 @default.
- W4386544762 hasLocation W43865447622 @default.
- W4386544762 hasOpenAccess W4386544762 @default.
- W4386544762 hasPrimaryLocation W43865447621 @default.
- W4386544762 hasRelatedWork W1470000624 @default.