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- W4386570147 endingPage "111694" @default.
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- W4386570147 abstract "Hydroxyl radicals (•OH) is one of the commonly reactive oxygen species available in biosystem and plays a key role in a number of physiological and pathological processes. Based on our previous study, fluoride could serve as a moderate electron donating group in constructing fluorescence probes. However, there is seldom work on the effects of fluoride-substituted moiety towards the photophysical properties in constructing fluorescence probes. In this work, we developed a series of novel fluorescence probes based on a quinolinium-scaffold containing fluoride substituted donor. From our results, the probe FHyR-3 which has an extended conjugated system could detect hydroxyl radical with high selectivity, sensitivity, and fast response. Furthermore, the probe has the maximum emission at 508 nm with a large stoke shift (114 nm) and exhibits low toxicity, good biocompatibility and mito-targeting. We also demonstrated its capability in tracking hydroxyl radical level in living cells and zebrafish." @default.
- W4386570147 created "2023-09-10" @default.
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- W4386570147 date "2023-12-01" @default.
- W4386570147 modified "2023-09-30" @default.
- W4386570147 title "Constructing fluorescence probes with fluoride-substituted donors for detecting •OH in living cells and zebrafish" @default.
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- W4386570147 doi "https://doi.org/10.1016/j.dyepig.2023.111694" @default.
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