Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386570181> ?p ?o ?g. }
- W4386570181 endingPage "132512" @default.
- W4386570181 startingPage "132512" @default.
- W4386570181 abstract "Pseudomonas aeruginosa, a versatile bacterium, has dual significance because of its beneficial roles in environmental soil processes and its detrimental effects as a nosocomial pathogen that causes clinical infections. Understanding adaptability to environmental stress is essential. This investigation delves into the complex interplay of two-component system (TCS), specifically ParRS and CprRS, as P. aeruginosa interprets host signals and navigates stress challenges. In this study, through phenotypic and proteomic analyses, the nuanced contributions of ParRS and CprRS to the pathogenesis and resilience mechanisms were elucidated. Furthermore, the indispensable roles of the ParS and CprS extracellular sensor domains in orchestrating signal perception remain unknown. Structural revelations imply a remarkable convergence of TCS sensors in interacting with host peptides, suggesting evolutionary strategies for bacterial adaptation. This pioneering work not only established links between cationic antimicrobial peptide (CAMP) resistance-associated TCSs and virulence modulation in nosocomial bacteria, but also transcended conventional boundaries. These implications extend beyond clinical resistance, permeating into the realm of soil revitalization and environmental guardianship. As it unveils P. aeruginosa intricacies, this study assumes a mantle of guiding strategies to mitigate clinical hazards, harness environmental advantages, and propel sustainable solutions forward." @default.
- W4386570181 created "2023-09-10" @default.
- W4386570181 creator A5007288954 @default.
- W4386570181 creator A5008790357 @default.
- W4386570181 creator A5026699951 @default.
- W4386570181 creator A5039768705 @default.
- W4386570181 creator A5047836899 @default.
- W4386570181 creator A5048957281 @default.
- W4386570181 creator A5051438193 @default.
- W4386570181 creator A5056905624 @default.
- W4386570181 creator A5085083319 @default.
- W4386570181 date "2023-10-01" @default.
- W4386570181 modified "2023-10-17" @default.
- W4386570181 title "Host-Derived Peptide Signals Regulate Pseudomonas aeruginosa Virulence Stress via the ParRS and CprRS Two-Component Systems" @default.
- W4386570181 cites W1531320623 @default.
- W4386570181 cites W1539796472 @default.
- W4386570181 cites W2030905386 @default.
- W4386570181 cites W2034541624 @default.
- W4386570181 cites W2058179337 @default.
- W4386570181 cites W2061927902 @default.
- W4386570181 cites W2072531703 @default.
- W4386570181 cites W2085275513 @default.
- W4386570181 cites W2106359046 @default.
- W4386570181 cites W2108226120 @default.
- W4386570181 cites W2139025447 @default.
- W4386570181 cites W2139382674 @default.
- W4386570181 cites W2158890744 @default.
- W4386570181 cites W2166780878 @default.
- W4386570181 cites W2168485847 @default.
- W4386570181 cites W2169605967 @default.
- W4386570181 cites W2179075918 @default.
- W4386570181 cites W2288590105 @default.
- W4386570181 cites W2600619077 @default.
- W4386570181 cites W2608551679 @default.
- W4386570181 cites W2624511782 @default.
- W4386570181 cites W2793506398 @default.
- W4386570181 cites W2793928847 @default.
- W4386570181 cites W2899737709 @default.
- W4386570181 cites W2911883905 @default.
- W4386570181 cites W2938823955 @default.
- W4386570181 cites W2939347585 @default.
- W4386570181 cites W2951173789 @default.
- W4386570181 cites W2964461511 @default.
- W4386570181 cites W2973457155 @default.
- W4386570181 cites W2977819875 @default.
- W4386570181 cites W2995594965 @default.
- W4386570181 cites W2998119265 @default.
- W4386570181 cites W3022690159 @default.
- W4386570181 cites W3114849484 @default.
- W4386570181 cites W3127895703 @default.
- W4386570181 cites W3128397839 @default.
- W4386570181 cites W3134223116 @default.
- W4386570181 cites W3134456118 @default.
- W4386570181 cites W3158209438 @default.
- W4386570181 cites W3165080560 @default.
- W4386570181 cites W3177828909 @default.
- W4386570181 cites W3201287276 @default.
- W4386570181 cites W3211805452 @default.
- W4386570181 cites W3212778000 @default.
- W4386570181 cites W3217389793 @default.
- W4386570181 cites W4206978588 @default.
- W4386570181 cites W4281666776 @default.
- W4386570181 cites W4282922306 @default.
- W4386570181 cites W4283522546 @default.
- W4386570181 cites W4297264900 @default.
- W4386570181 cites W4366588495 @default.
- W4386570181 doi "https://doi.org/10.1016/j.jhazmat.2023.132512" @default.
- W4386570181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37703740" @default.
- W4386570181 hasPublicationYear "2023" @default.
- W4386570181 type Work @default.
- W4386570181 citedByCount "0" @default.
- W4386570181 crossrefType "journal-article" @default.
- W4386570181 hasAuthorship W4386570181A5007288954 @default.
- W4386570181 hasAuthorship W4386570181A5008790357 @default.
- W4386570181 hasAuthorship W4386570181A5026699951 @default.
- W4386570181 hasAuthorship W4386570181A5039768705 @default.
- W4386570181 hasAuthorship W4386570181A5047836899 @default.
- W4386570181 hasAuthorship W4386570181A5048957281 @default.
- W4386570181 hasAuthorship W4386570181A5051438193 @default.
- W4386570181 hasAuthorship W4386570181A5056905624 @default.
- W4386570181 hasAuthorship W4386570181A5085083319 @default.
- W4386570181 hasConcept C104317684 @default.
- W4386570181 hasConcept C2777637488 @default.
- W4386570181 hasConcept C523546767 @default.
- W4386570181 hasConcept C54355233 @default.
- W4386570181 hasConcept C60987743 @default.
- W4386570181 hasConcept C70721500 @default.
- W4386570181 hasConcept C86803240 @default.
- W4386570181 hasConcept C89423630 @default.
- W4386570181 hasConcept C95444343 @default.
- W4386570181 hasConceptScore W4386570181C104317684 @default.
- W4386570181 hasConceptScore W4386570181C2777637488 @default.
- W4386570181 hasConceptScore W4386570181C523546767 @default.
- W4386570181 hasConceptScore W4386570181C54355233 @default.
- W4386570181 hasConceptScore W4386570181C60987743 @default.
- W4386570181 hasConceptScore W4386570181C70721500 @default.
- W4386570181 hasConceptScore W4386570181C86803240 @default.
- W4386570181 hasConceptScore W4386570181C89423630 @default.