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- W4386571887 abstract "Abstract Resection is the only potential curative treatment for perihilar cholangiocarcinoma (PHC); however, complete resection is often technically challenging due to the anatomical location. Various innovative approaches and procedures were invented to circumvent this limitation but the rates of postoperative morbidity (20%–78%) and mortality (2%–15%) are still high. In patients diagnosed with resectable PHC, deliberate and coordinated preoperative workup and optimization of the patient and future liver remnant are crucial. Biliary drainage is recommended to relieve obstructive jaundice and optimize the clinical condition before liver resection. Biliary drainage for PHC can be performed either by endoscopic biliary drainage or percutaneous transhepatic biliary drainage. To date there is no consensus about which method is preferred. The volumetric assessment of the future remnant liver volume and optimization mainly using portal vein embolization is the gold standard in the management of the risk to develop post hepatectomy liver failure. The improvement of systemic chemotherapy has contributed to prolong the survival not only in patients with unresectable PHC but also in patients undergoing curative surgery. In this article, we review the literature and discuss the current surgical treatment of PHC." @default.
- W4386571887 created "2023-09-10" @default.
- W4386571887 creator A5036787727 @default.
- W4386571887 creator A5075220614 @default.
- W4386571887 creator A5081087339 @default.
- W4386571887 creator A5082302691 @default.
- W4386571887 creator A5086043059 @default.
- W4386571887 date "2023-09-08" @default.
- W4386571887 modified "2023-10-16" @default.
- W4386571887 title "Essential updates 2021/2022: Update in surgical strategy for perihilar cholangiocarcinoma" @default.
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- W4386571887 doi "https://doi.org/10.1002/ags3.12734" @default.
- W4386571887 hasPublicationYear "2023" @default.
- W4386571887 type Work @default.