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- W4386575419 endingPage "126825" @default.
- W4386575419 startingPage "126825" @default.
- W4386575419 abstract "Teichoic acid (TA) is a weakly anionic polymer present in the cell walls of Gram-positive bacteria. It can be classified into wall teichoic acid (WTA) and lipoteichoic acid (LTA) based on its localization in the cell wall. The structure and biosynthetic pathway of TAs are strain-specific and have a significant role in maintaining cell wall stability. TAs have various beneficial functions, such as immunomodulatory, anticancer and antioxidant activities. However, the purity and yield of TAs are generally not high, and different isolation methods may even affect their structural integrity, which limits the research progress on the probiotic functions of TA. This paper reviews an overview of the structure and biosynthetic pathway of TAs in different strains, as well as the research progress of the isolation and purification methods of TAs. Furthermore, this review also highlights the current research status on the biological functions of TAs. Through a comprehensive understanding of this review, it is expected to pave the way for advancements in isolating and purifying high-quality TAs and, in turn, lay a foundation for contributing to the development of targeted probiotic therapies." @default.
- W4386575419 created "2023-09-10" @default.
- W4386575419 creator A5019191174 @default.
- W4386575419 creator A5031973958 @default.
- W4386575419 creator A5072926282 @default.
- W4386575419 creator A5080535538 @default.
- W4386575419 creator A5090532858 @default.
- W4386575419 date "2023-12-01" @default.
- W4386575419 modified "2023-10-14" @default.
- W4386575419 title "Insight into the structure, biosynthesis, isolation method and biological function of teichoic acid in different gram-positive microorganisms: A review" @default.
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