Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386580971> ?p ?o ?g. }
- W4386580971 abstract "Given the increase in ultra-processed food (UPF) consumption, their potential health effects have aroused concern. Whether UPF consumption is associated with cancer and cardiovascular disease mortality is debatable. This study evaluates the association of UPF consumption with mortality.A total of 108,714 U.S. adults from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (1993-2001), 208,051 UK adults from UK Biobank (2006-2010), and 41,070 U.S. adults from National Health and Nutrition Examination Survey (1999-2018) were included. Dietary data were collected by dietary questionnaire and classified using the NOVA classification. UPF consumption was expressed as the weight proportion of UPFs in total foods consumed. Cox proportional hazard models were used to calculate hazard ratios and 95% CIs. Mediation analysis was used to evaluate whether multiple metabolic pathways mediated the associations in UK Biobank. Analyses were performed in 2022-2023.Combined analyses of the three cohorts showed that those with the highest quartile of UPF consumption had higher risks of all-cause mortality (hazard ratio, 1.16; 95% CI, 1.11-1.20) and cardiovascular disease mortality (hazard ratio, 1.17; 95% CI, 1.06-1.28) compared to the lowest quartile of UPF consumption. UPF consumption was not associated with cancer mortality risk. Biomarkers of liver function have the greatest mediating effects on all-cause mortality (20.3%), and biomarkers of inflammation have the greatest mediating effects on cardiovascular disease mortality (29.2%).Higher UPF consumption was associated with increased all-cause and cardiovascular disease mortality risk, with multiple metabolic pathways playing mediating roles." @default.
- W4386580971 created "2023-09-10" @default.
- W4386580971 creator A5000254862 @default.
- W4386580971 creator A5027240571 @default.
- W4386580971 creator A5027792053 @default.
- W4386580971 creator A5028741394 @default.
- W4386580971 creator A5032100484 @default.
- W4386580971 creator A5046188481 @default.
- W4386580971 creator A5051610166 @default.
- W4386580971 creator A5057854541 @default.
- W4386580971 creator A5061704853 @default.
- W4386580971 creator A5064495035 @default.
- W4386580971 creator A5065058975 @default.
- W4386580971 creator A5065232759 @default.
- W4386580971 creator A5066107958 @default.
- W4386580971 creator A5072580346 @default.
- W4386580971 creator A5080528385 @default.
- W4386580971 creator A5082476673 @default.
- W4386580971 date "2023-09-01" @default.
- W4386580971 modified "2023-10-02" @default.
- W4386580971 title "Ultra-processed food consumption and mortality: three cohort studies in the United States and United Kingdom" @default.
- W4386580971 cites W1502898407 @default.
- W4386580971 cites W1789164482 @default.
- W4386580971 cites W1941424948 @default.
- W4386580971 cites W2082704080 @default.
- W4386580971 cites W2092696502 @default.
- W4386580971 cites W2113002312 @default.
- W4386580971 cites W2141662760 @default.
- W4386580971 cites W2144802824 @default.
- W4386580971 cites W2147687825 @default.
- W4386580971 cites W2315464131 @default.
- W4386580971 cites W2407467502 @default.
- W4386580971 cites W2723723801 @default.
- W4386580971 cites W2734898792 @default.
- W4386580971 cites W2792720753 @default.
- W4386580971 cites W2899736836 @default.
- W4386580971 cites W2903767612 @default.
- W4386580971 cites W2911640446 @default.
- W4386580971 cites W2911872206 @default.
- W4386580971 cites W2917808568 @default.
- W4386580971 cites W2946281272 @default.
- W4386580971 cites W2947904584 @default.
- W4386580971 cites W2964474706 @default.
- W4386580971 cites W3006062621 @default.
- W4386580971 cites W3016302378 @default.
- W4386580971 cites W3112124609 @default.
- W4386580971 cites W3112715522 @default.
- W4386580971 cites W3124608917 @default.
- W4386580971 cites W3143760019 @default.
- W4386580971 cites W3154717121 @default.
- W4386580971 cites W3157346013 @default.
- W4386580971 cites W3173304857 @default.
- W4386580971 cites W3173855984 @default.
- W4386580971 cites W3200619739 @default.
- W4386580971 cites W3202712388 @default.
- W4386580971 cites W3205519222 @default.
- W4386580971 cites W4206679194 @default.
- W4386580971 cites W4212980877 @default.
- W4386580971 cites W4221051815 @default.
- W4386580971 cites W4291963995 @default.
- W4386580971 cites W4292811746 @default.
- W4386580971 cites W4293092489 @default.
- W4386580971 cites W4294161571 @default.
- W4386580971 cites W4303962244 @default.
- W4386580971 cites W4304775382 @default.
- W4386580971 cites W4315754639 @default.
- W4386580971 cites W4318678064 @default.
- W4386580971 cites W4323308389 @default.
- W4386580971 doi "https://doi.org/10.1016/j.amepre.2023.09.005" @default.
- W4386580971 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37690589" @default.
- W4386580971 hasPublicationYear "2023" @default.
- W4386580971 type Work @default.
- W4386580971 citedByCount "0" @default.
- W4386580971 crossrefType "journal-article" @default.
- W4386580971 hasAuthorship W4386580971A5000254862 @default.
- W4386580971 hasAuthorship W4386580971A5027240571 @default.
- W4386580971 hasAuthorship W4386580971A5027792053 @default.
- W4386580971 hasAuthorship W4386580971A5028741394 @default.
- W4386580971 hasAuthorship W4386580971A5032100484 @default.
- W4386580971 hasAuthorship W4386580971A5046188481 @default.
- W4386580971 hasAuthorship W4386580971A5051610166 @default.
- W4386580971 hasAuthorship W4386580971A5057854541 @default.
- W4386580971 hasAuthorship W4386580971A5061704853 @default.
- W4386580971 hasAuthorship W4386580971A5064495035 @default.
- W4386580971 hasAuthorship W4386580971A5065058975 @default.
- W4386580971 hasAuthorship W4386580971A5065232759 @default.
- W4386580971 hasAuthorship W4386580971A5066107958 @default.
- W4386580971 hasAuthorship W4386580971A5072580346 @default.
- W4386580971 hasAuthorship W4386580971A5080528385 @default.
- W4386580971 hasAuthorship W4386580971A5082476673 @default.
- W4386580971 hasConcept C126322002 @default.
- W4386580971 hasConcept C144024400 @default.
- W4386580971 hasConcept C149923435 @default.
- W4386580971 hasConcept C201903717 @default.
- W4386580971 hasConcept C207103383 @default.
- W4386580971 hasConcept C2779134260 @default.
- W4386580971 hasConcept C2779874844 @default.
- W4386580971 hasConcept C2908647359 @default.
- W4386580971 hasConcept C44249647 @default.
- W4386580971 hasConcept C50382708 @default.